Success Metrics

Clinical Success Rate
88.9%

Based on 56 completed trials

Completion Rate
89%(56/63)
Active Trials
3(3%)
Results Posted
73%(41 trials)
Terminated
7(8%)

Phase Distribution

Ph early_phase_1
8
9%
Ph phase_2
34
39%
Ph phase_3
11
13%
Ph phase_4
15
17%
Ph phase_1
3
3%
Ph not_applicable
16
18%

Phase Distribution

11

Early Stage

34

Mid Stage

26

Late Stage

Phase Distribution87 total trials
Early Phase 1First-in-human
8(9.2%)
Phase 1Safety & dosage
3(3.4%)
Phase 2Efficacy & side effects
34(39.1%)
Phase 3Large-scale testing
11(12.6%)
Phase 4Post-market surveillance
15(17.2%)
N/ANon-phased studies
16(18.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

76.7%

56 of 73 finished

Non-Completion Rate

23.3%

17 ended early

Currently Active

3

trials recruiting

Total Trials

87

all time

Status Distribution
Active(4)
Completed(56)
Terminated(17)
Other(10)

Detailed Status

Completed56
unknown10
Withdrawn10
Terminated7
Recruiting2
Not yet recruiting1

Development Timeline

Analytics

Development Status

Total Trials
87
Active
3
Success Rate
88.9%
Most Advanced
Phase 4

Trials by Phase

Early Phase 18 (9.2%)
Phase 13 (3.4%)
Phase 234 (39.1%)
Phase 311 (12.6%)
Phase 415 (17.2%)
N/A16 (18.4%)

Trials by Status

completed5664%
not_yet_recruiting11%
unknown1011%
withdrawn1011%
recruiting22%
active_not_recruiting11%
terminated78%

Recent Activity

3 active trials
Showing 5 of 87
recruitingphase_4

Varenicline and Accelerated Transcranial Magnetic Stimulation (TMS) for Quitting Nicotine Use (Pilot Study)

NCT07145866
completedearly_phase_1

Dose Timing of D-Cycloserine to Augment CBT for Social Anxiety Disorder

NCT02066792
not_yet_recruitingphase_1

Synaptic Mechanisms of Intermittent Theta Burst Stimulation for Major Depressive Disorder

NCT07593222
terminatedphase_2

D-cycloserine for the Treatment of Chronic, Refractory Low Back Pain

NCT03535688
completedphase_4

D-Cycloserine for Serine Palmitoyltransferase Inhibition

NCT07542548
View all 87 trials

Clinical Trials (87)

Showing 20 of 87 trialsScroll for more
NCT07145866Phase 4

Varenicline and Accelerated Transcranial Magnetic Stimulation (TMS) for Quitting Nicotine Use (Pilot Study)

Recruiting
NCT02066792Early Phase 1

Dose Timing of D-Cycloserine to Augment CBT for Social Anxiety Disorder

Completed
NCT07593222Phase 1

Synaptic Mechanisms of Intermittent Theta Burst Stimulation for Major Depressive Disorder

Not Yet Recruiting
NCT03535688Phase 2

D-cycloserine for the Treatment of Chronic, Refractory Low Back Pain

Terminated
NCT07542548Phase 4

D-Cycloserine for Serine Palmitoyltransferase Inhibition

Completed
NCT03780829Early Phase 1

AIH for Spinal Cord Repair

Terminated
NCT05994703Phase 2

Assisting Smokers to Switch to an e-Cigarette by Accelerating Learning of Adaptive Habits Using D-cycloserine

Completed
NCT05591677Phase 2

D-Cycloserine Augmentation of Intermittent Theta Burst Stimulation (iTBS) in Depression (COGENT)

Active Not Recruiting
NCT05395494Phase 2

iTBS-DCS in Fibromyalgia

Terminated
NCT06121284Phase 2

iTBS+D-Cycloserine for Youth Suicide

Recruiting
NCT01450306Not Applicable

Exposure, D-cycloserine Enhancement, and Functional Magnetic Resonance Imaging (fMRI) in Snake Phobics

Completed
NCT05177601Phase 2

iTBS-DCS in Obsessive Compulsive Disorder

Unknown
NCT05731323Phase 1

D-Cycloserine+iTBS PK Study

Completed
NCT02385266Phase 4

Treating Urological Chronic Pelvic Pain Syndrome (UCPPS) Pain

Terminated
NCT04357951Early Phase 1

D-cycloserine Augmented Treatment for Youth With Tic Disorders

Withdrawn
NCT03216356Phase 2

Effect of D-cycloserine on a Short Imagery Rescripting Intervention for Subclinical PTSD

Withdrawn
NCT01512316Not Applicable

Exploring Learning and Unlearning of Fear

Withdrawn
NCT04762836Not Applicable

Pain, Learning, and Nocebo

Completed
NCT03937596Phase 2

Adjunctive D-Cycloserine in Major Depressive Disorder

Completed
NCT02635893Phase 4

Lower Limb Function After Spinal Cord Injury

Completed

Drug Details

Intervention Type
DRUG
Total Trials
87