Success Metrics

Clinical Success Rate
84.5%

Based on 49 completed trials

Completion Rate
84%(49/58)
Active Trials
42(37%)
Results Posted
63%(31 trials)
Terminated
9(8%)

Phase Distribution

Ph early_phase_1
1
1%
Ph phase_3
20
18%
Ph phase_2
42
37%
Ph phase_4
13
11%
Ph not_applicable
5
4%
Ph phase_1
32
28%

Phase Distribution

33

Early Stage

42

Mid Stage

33

Late Stage

Phase Distribution113 total trials
Early Phase 1First-in-human
1(0.9%)
Phase 1Safety & dosage
32(28.3%)
Phase 2Efficacy & side effects
42(37.2%)
Phase 3Large-scale testing
20(17.7%)
Phase 4Post-market surveillance
13(11.5%)
N/ANon-phased studies
5(4.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

81.7%

49 of 60 finished

Non-Completion Rate

18.3%

11 ended early

Currently Active

42

trials recruiting

Total Trials

114

all time

Status Distribution
Active(44)
Completed(49)
Terminated(11)
Other(10)

Detailed Status

Completed49
Recruiting30
Active, not recruiting12
unknown10
Terminated9
Not yet recruiting2

Development Timeline

Analytics

Development Status

Total Trials
114
Active
42
Success Rate
84.5%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (0.9%)
Phase 132 (28.3%)
Phase 242 (37.2%)
Phase 320 (17.7%)
Phase 413 (11.5%)
N/A5 (4.4%)

Trials by Status

active_not_recruiting1211%
unknown109%
not_yet_recruiting22%
completed4943%
recruiting3026%
terminated98%
withdrawn22%

Recent Activity

Clinical Trials (114)

Showing 20 of 114 trialsScroll for more
NCT06124157Phase 2

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

Recruiting
NCT06317662Phase 2

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

Recruiting
NCT04043494Phase 3

International Cooperative Treatment Protocol for Children and Adolescents With Lymphoblastic Lymphoma

Recruiting
NCT02112916Phase 3

Combination Chemotherapy With or Without Bortezomib in Treating Younger Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or Stage II-IV T-Cell Lymphoblastic Lymphoma

Active Not Recruiting
NCT06390319Phase 2

Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL)

Recruiting
NCT06289673Phase 4

Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma

Recruiting
NCT02003222Phase 3

Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT06533748Phase 2

Therapy for Newly Diagnosed Patients With B-Cell Precursor Acute Lymphoblastic Leukemia and Lymphoma

Recruiting
NCT03164057Phase 2

A Trial of Epigenetic Priming in Patients With Newly Diagnosed Acute Myeloid Leukemia

Active Not Recruiting
NCT05886049Phase 1

Testing the Addition of an Anti-cancer Drug, SNDX-5613, to the Standard Chemotherapy Treatment (Daunorubicin and Cytarabine) for Newly Diagnosed Patients With Acute Myeloid Leukemia That Has Changes in NPM1 or MLL/KMT2A Gene

Recruiting
NCT07052994Phase 1

A Phase Ia/Ib Trial of Revumenib Combined With Cytarabine, Daunorubicin, and Gemtuzumab Ozogamicin (GO) in Frontline and Relapsed /Refractory Pediatric Acute Leukemia Patients

Not Yet Recruiting
NCT07007312Phase 3

Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML

Recruiting
NCT06744504Phase 3

Standard-dose vs Intermediate-dose Cytarabine Induction in the Treatment of Acute Myeloid Leukemia With RUNX1-RUNX1T1

Recruiting
NCT06313437Phase 1

Revumenib in Combination With 7+3 + Midostaurin in AML

Recruiting
NCT05735184Phase 1

A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

Recruiting
NCT07255872Phase 2

A Study of BL-M11D1 in Combination With Cytarabine + Daunorubicin or Venetoclax + Azacitidine in Patients With Acute Myeloid Leukemia

Not Yet Recruiting
NCT02523976Phase 2

Dasatinib Combined With Chemotherapy in Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia

Completed
NCT03568994Early Phase 1

Atovaquone (Mepron®) Combined With Conventional Chemotherapy for de Novo Acute Myeloid Leukemia (AML)

Completed
NCT07228273Phase 2

Induction and Consolidation With Fludarabine, Cytarabine, Idarubicin, and Venetoclax for the Treatment of Acute Myeloid Leukemia

Recruiting
NCT03701308Phase 2

Daunorubicin and Cytarabine With or Without Uproleselan in Treating Older Adult Patients With Acute Myeloid Leukemia Receiving Intensive Induction Chemotherapy

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
114