Success Metrics

Clinical Success Rate
84.7%

Based on 50 completed trials

Completion Rate
85%(50/59)
Active Trials
42(37%)
Results Posted
62%(31 trials)
Terminated
9(8%)

Phase Distribution

Ph phase_4
13
11%
Ph phase_1
32
28%
Ph early_phase_1
1
1%
Ph phase_2
43
37%
Ph phase_3
20
17%
Ph not_applicable
5
4%

Phase Distribution

33

Early Stage

43

Mid Stage

33

Late Stage

Phase Distribution114 total trials
Early Phase 1First-in-human
1(0.9%)
Phase 1Safety & dosage
32(28.1%)
Phase 2Efficacy & side effects
43(37.7%)
Phase 3Large-scale testing
20(17.5%)
Phase 4Post-market surveillance
13(11.4%)
N/ANon-phased studies
5(4.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

80.6%

50 of 62 finished

Non-Completion Rate

19.4%

12 ended early

Currently Active

42

trials recruiting

Total Trials

115

all time

Status Distribution
Active(43)
Completed(50)
Terminated(12)
Other(10)

Detailed Status

Completed50
Recruiting28
Active, not recruiting14
unknown10
Terminated9
Withdrawn3

Development Timeline

Analytics

Development Status

Total Trials
115
Active
42
Success Rate
84.7%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (0.9%)
Phase 132 (28.1%)
Phase 243 (37.7%)
Phase 320 (17.5%)
Phase 413 (11.4%)
N/A5 (4.4%)

Trials by Status

completed5043%
active_not_recruiting1412%
unknown109%
not_yet_recruiting11%
recruiting2824%
terminated98%
withdrawn33%

Recent Activity

Clinical Trials (115)

Showing 20 of 115 trialsScroll for more
NCT02003222Phase 3

Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT06317662Phase 2

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

Recruiting
NCT02112916Phase 3

Combination Chemotherapy With or Without Bortezomib in Treating Younger Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or Stage II-IV T-Cell Lymphoblastic Lymphoma

Active Not Recruiting
NCT06124157Phase 2

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

Recruiting
NCT07007312Phase 3

Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML

Recruiting
NCT03836209Phase 2

Gilteritinib vs Midostaurin in FLT3 Mutated Acute Myeloid Leukemia

Completed
NCT05886049Phase 1

A Phase 1b Study of Menin Inhibitor SNDX- 5613 in Combination With Daunorubicin and Cytarabine in Newly Diagnosed Patients With Acute Myeloid Leukemia and NPM1 Mutated/FLT3 Wildtype or MLL/KMT2A Rearranged or NUP98 Alterations Disease

Recruiting
NCT02416388Phase 2

Study to Improve OS in 18 to 60 Year-old Patients, Comparing Daunorubicin Versus High Dose Idarubicin Induction Regimens, High Dose Versus Intermediate Dose Cytarabine Consolidation Regimens, and Standard Versus MMF Prophylaxis of GvHD in Allografted Patients in First CR

Recruiting
NCT06533748Phase 2

Therapy for Newly Diagnosed Patients With B-Cell Precursor Acute Lymphoblastic Leukemia and Lymphoma

Recruiting
NCT06390319Phase 2

Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL)

Recruiting
NCT06289673Phase 4

Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma

Recruiting
NCT04659616Phase 1

Pemigatinib After Chemotherapy for the Treatment of Newly Diagnosed Acute Myeloid Leukemia

Recruiting
NCT07228273Phase 2

Induction and Consolidation With Fludarabine, Cytarabine, Idarubicin, and Venetoclax for the Treatment of Acute Myeloid Leukemia

Recruiting
NCT02393859Phase 3

Phase 3 Trial of Blinatumomab vs Standard Chemotherapy in Pediatric Subjects With HIgh-Risk (HR) First Relapse B-precursor Acute Lymphoblastic Leukemia (ALL)

Completed
NCT03709758Phase 1

Venetoclax in Combination With Intensive Induction and Consolidation Chemotherapy in Treatment Naïve AML

Active Not Recruiting
NCT03568994Early Phase 1

Atovaquone (Mepron®) Combined With Conventional Chemotherapy for de Novo Acute Myeloid Leukemia (AML)

Completed
NCT03117751Phase 2

Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and Lymphoma

Active Not Recruiting
NCT07052994Phase 1

A Phase Ia/Ib Trial of Revumenib Combined With Cytarabine, Daunorubicin, and Gemtuzumab Ozogamicin (GO) in Frontline and Relapsed /Refractory Pediatric Acute Leukemia Patients

Withdrawn
NCT02632708Phase 1

Safety Study of AG-120 or AG-221 in Combination With Induction and Consolidation Therapy in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) With an IDH1 and/or IDH2 Mutation

Active Not Recruiting
NCT06744556Phase 2

HAV Versus DAV/IAV Induction Regimen in Elderly Patients With AML

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
115