Success Metrics

Active Trials
16(89%)

Phase Distribution

Ph phase_1
3
17%
Ph phase_2
8
44%
Ph phase_3
6
33%

Phase Distribution

3

Early Stage

8

Mid Stage

6

Late Stage

Phase Distribution17 total trials
Phase 1Safety & dosage
3(17.6%)
Phase 2Efficacy & side effects
8(47.1%)
Phase 3Large-scale testing
6(35.3%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

0.0%

0 of 1 finished

Non-Completion Rate

100.0%

1 ended early

Currently Active

16

trials recruiting

Total Trials

18

all time

Status Distribution
Active(16)
Terminated(1)
Other(1)

Detailed Status

Recruiting9
Active, not recruiting7
unknown1
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
18
Active
16
Success Rate
N/A
Most Advanced
Phase 3

Trials by Phase

Phase 13 (17.6%)
Phase 28 (47.1%)
Phase 36 (35.3%)

Trials by Status

active_not_recruiting739%
recruiting950%
unknown16%
withdrawn16%

Recent Activity

Clinical Trials (18)

Showing 18 of 18 trials
NCT06350097Phase 3

Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer

Recruiting
NCT01042379Phase 2

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

Recruiting
NCT03742102Phase 1

A Study of Novel Anti-cancer Agents in Patients With Metastatic Triple Negative Breast Cancer

Active Not Recruiting
NCT07069595Phase 2

PREDICT-RD: ctDNA Surveillance in TNBC With Residual Disease

Recruiting
NCT05687266Phase 3

Phase III, Open-label, First-line Study of Dato-DXd in Combination With Durvalumab and Carboplatin for Advanced NSCLC Without Actionable Genomic Alterations

Active Not Recruiting
NCT05555732Phase 3

Datopotamab Deruxtecan (Dato-DXd) and Pembrolizumab With or Without Platinum Chemotherapy in 1L Non-Small Cell Lung Cancer (TROPION-Lung07)

Active Not Recruiting
NCT06357533Phase 3

Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations

Recruiting
NCT06564844Phase 3

A Phase III, Randomised Study of Adjuvant Dato-DXd in Combination With Rilvegostomig or Rilvegostomig Monotherapy Versus Standard of Care, Following Complete Tumour Resection, in Participants With Stage I Adenocarcinoma NSCLC Who Are ctDNA-positive or Have High-risk Pathological Features

Active Not Recruiting
NCT05215340Phase 3

Study of Dato-DXd Plus Pembrolizumab vs Pembrolizumab Alone in the First-line Treatment of Subjects With Advanced or Metastatic NSCLC Without Actionable Genomic Alterations

Recruiting
NCT04612751Phase 1

Phase 1b Study of Dato-DXd in Combination With Immunotherapy With or Without Carboplatin in Advanced or Metastatic Non-Small Cell Lung Cancer

Active Not Recruiting
NCT06533826Phase 2

TReatment of ADC-Refractory Breast CancEr With Dato-DXd or T-DXd: TRADE DXd

Recruiting
NCT06822543Phase 2

A Single Arm, Phase 2 Study of Datopotamab Deruxtecan, Carboplatin, and Pembrolizumab for Treatment-naive Brain Metastases From NSCLC (Non-small Cell Lung Cancer)

Recruiting
NCT05866432Phase 2

Phase II Study of Dato-DXd in Triple-negative Breast Cancer Patients With Newly Diagnosed or Progressing Brain Metastases

Recruiting
NCT06676917Phase 2

Datopotamab Deruxtecan (Dato-DXd) for Non-Small Cell Lung Cancer (NSCLC) Patients With Active Brain Metastases

Withdrawn
NCT06176261Phase 2

DATO-BASE: DATOpotamab-deruxtecan for Breast Cancer Brain metAstaSEs

Recruiting
NCT06279728

Medical Access Program for Datopotamab Deruxtecan in EGFRm NSCLC Patients

Unknown
NCT04526691Phase 1

Datopotamab Deruxtecan (Dato-DXd) in Combination With Pembrolizumab With or Without Platinum Chemotherapy in Subjects With Advanced or Metastatic Non-Small Cell Lung Cancer (TROPION-Lung02)

Active Not Recruiting
NCT03944772Phase 2

Phase 2 Platform Study in Patients With Advanced Non-Small Lung Cancer Who Progressed on First-Line Osimertinib Therapy (ORCHARD)

Active Not Recruiting

All 18 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
18