Success Metrics

Clinical Success Rate
75.0%

Based on 9 completed trials

Completion Rate
75%(9/12)
Active Trials
39(65%)
Results Posted
22%(2 trials)
Terminated
3(5%)

Phase Distribution

Ph phase_3
10
17%
Ph phase_4
1
2%
Ph early_phase_1
1
2%
Ph phase_2
26
43%
Ph phase_1
17
28%

Phase Distribution

18

Early Stage

26

Mid Stage

11

Late Stage

Phase Distribution55 total trials
Early Phase 1First-in-human
1(1.8%)
Phase 1Safety & dosage
17(30.9%)
Phase 2Efficacy & side effects
26(47.3%)
Phase 3Large-scale testing
10(18.2%)
Phase 4Post-market surveillance
1(1.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

69.2%

9 of 13 finished

Non-Completion Rate

30.8%

4 ended early

Currently Active

39

trials recruiting

Total Trials

60

all time

Status Distribution
Active(47)
Completed(9)
Terminated(4)

Detailed Status

Recruiting27
Active, not recruiting12
Completed9
Not yet recruiting8
Terminated3
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
60
Active
39
Success Rate
75.0%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (1.8%)
Phase 117 (30.9%)
Phase 226 (47.3%)
Phase 310 (18.2%)
Phase 41 (1.8%)

Trials by Status

completed915%
not_yet_recruiting813%
recruiting2745%
terminated35%
withdrawn12%
active_not_recruiting1220%

Recent Activity

Clinical Trials (60)

Showing 20 of 60 trialsScroll for more
NCT05669664Phase 2

Testing the Anti-cancer Drug Darolutamide in Patients With Testosterone-Driven Salivary Gland Cancers

Active Not Recruiting
NCT06625970Phase 3

Study Evaluating the Efficacy and Safety of Darolutamide and Stereotactic Dose Escalated Radiotherapy in Patients With Localized Prostate Cancer and High-risk Features of Relapse

Recruiting
NCT06120491Phase 3

Saruparib (AZD5305) vs Placebo in Men With Metastatic Castration-Sensitive Prostate Cancer Receiving Physician's Choice New Hormonal Agents

Active Not Recruiting
NCT07730151Phase 2

Efficacy and Safety of Darolutamide Combined With Docetaxel and ADT as Neoadjuvant Therapy for Locally Advanced Prostate Cancer.

Not Yet Recruiting
NCT06169124Phase 2

Study to Test the Drug Darolutamide Along With the Drugs Leuprolide Acetate and Exemestane in Patients With Recurrent Ovarian Granulosa Cell Tumors

Active Not Recruiting
NCT04484818Phase 3

Testing the Addition of Darolutamide to Hormonal Therapy (Androgen Deprivation Therapy [ADT]) After Surgery for Men With High-Risk Prostate Cancer, The ERADICATE Study

Active Not Recruiting
NCT07723248Phase 3

A Study to Learn About the Investigational Drug Rinzimetostat (ORIC-944) in Patients With mCRPC Who Were Previously Treated With Abiraterone Acetate (Himalayas-1)

Recruiting
NCT06378866Phase 2

Stereotactic Body Radiation Therapy Plus Immediate or Delayed Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy or Salvage Radiation Therapy for the Treatment of Prostate Cancer, DIVINE Trial

Recruiting
NCT07711002Phase 3

Saruparib in Combination With Physician's Choice of ARPI in Patients With mHSPC Previously Treated With Docetaxel or 177Lu-PSMA Therapy Without Disease Progression and PSA ≥ 0.2 ng/mL (EvoPAR-PR05)

Not Yet Recruiting
NCT07406282

A Study to Learn About Real-world Utilization and Outcomes of Darolutamide and Other Androgen Receptor Pathway Inhibitors (ARPIs) for Newly Diagnosed Metastatic Hormone-sensitive Prostate Cancer (de Novo mHSPC) in US Urology Clinics

Recruiting
NCT05818683Phase 1

A Study of Pasritamig (JNJ-78278343) in Combination With Other Agents for Metastatic Prostate Cancer

Recruiting
NCT07140900Phase 1

Study Evaluating the Safety, Tolerability, and Efficacy of Xaluritamig in Combination With Androgen Receptor Pathway Inhibitors in Participants With Metastatic Hormone-sensitive Prostate Cancer

Recruiting
NCT06401980Phase 2

Darolutamide in Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Recruiting
NCT07611110Phase 3

AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)

Recruiting
NCT05938270Phase 1

A Study to Investigate the Biological Effects of Saruparib (AZD5305), Darolutamide, and in Combination in Men With Newly Diagnosed Prostate Cancer.

Completed
NCT07538843

An Observational Study Conducted in China to Evaluate the Efficacy and Safety of Darolutamide in Combination With Androgen Deprivation Therapy (ADT) for Men With Non-metastatic Prostate Cancer That Progressed Following Prior Bicalutamide + ADT Treatment

Not Yet Recruiting
NCT05999968Phase 1

Abemaciclib Plus Darolutamide in Prostate Cancer That Has Spread After Initial Treatment

Terminated
NCT05050084Phase 3

Two Studies for Patients With Unfavorable Intermediate Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a Higher Gene Risk Score, The Guidance Trial

Active Not Recruiting
NCT06220864Phase 1

SNV1521 in Participants With Advanced Solid Tumors

Recruiting
NCT07450599Phase 2

A Study to Learn How Well a Combination of Darolutamide and Androgen Deprivation Therapy (ADT) Works as a Treatment Before Surgery for Men Who Have High-risk Localized Prostate Cancer.

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
60