Success Metrics

Clinical Success Rate
76.9%

Based on 10 completed trials

Completion Rate
77%(10/13)
Active Trials
39(65%)
Results Posted
40%(4 trials)
Terminated
3(5%)

Phase Distribution

Ph phase_4
1
2%
Ph phase_3
10
17%
Ph phase_1
16
27%
Ph early_phase_1
1
2%
Ph phase_2
27
45%

Phase Distribution

17

Early Stage

27

Mid Stage

11

Late Stage

Phase Distribution55 total trials
Early Phase 1First-in-human
1(1.8%)
Phase 1Safety & dosage
16(29.1%)
Phase 2Efficacy & side effects
27(49.1%)
Phase 3Large-scale testing
10(18.2%)
Phase 4Post-market surveillance
1(1.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

71.4%

10 of 14 finished

Non-Completion Rate

28.6%

4 ended early

Currently Active

39

trials recruiting

Total Trials

60

all time

Status Distribution
Active(46)
Completed(10)
Terminated(4)

Detailed Status

Recruiting28
Active, not recruiting11
Completed10
Not yet recruiting7
Terminated3
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
60
Active
39
Success Rate
76.9%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (1.8%)
Phase 116 (29.1%)
Phase 227 (49.1%)
Phase 310 (18.2%)
Phase 41 (1.8%)

Trials by Status

recruiting2847%
terminated35%
not_yet_recruiting712%
withdrawn12%
active_not_recruiting1118%
completed1017%

Recent Activity

Clinical Trials (60)

Showing 20 of 60 trialsScroll for more
NCT07852195Phase 2

Testing the Use of High Dose Testosterone Followed by Darolutamide Compared to the Usual Care for Patients With Metastatic Prostate Cancer

Not Yet Recruiting
NCT07190300Phase 1

TulmiSTAR-02: A Phase I/II Open-label Study of Tulmimetostat in Combination With Darolutamide vs. Darolutamide, and Tulmimetostat With Abiraterone in Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

Recruiting
NCT03568656Phase 1

Study to Evaluate CCS1477 in Advanced Tumours

Completed
NCT05818683Phase 1

A Study of Pasritamig (JNJ-78278343) in Combination With Other Agents for Metastatic Prostate Cancer

Recruiting
NCT04335682Phase 2

Androgen Receptor Directed Therapy on Cognitive Function in Patients Treated With Darolutamide or Enzalutamide

Completed
NCT07620041Phase 1

Phase I Study of QLC5508 in Advanced Solid Tumors: C-QTc, Pharmacokinetics (PK) Comparisons and Drug-drug Interaction

Recruiting
NCT05762536Phase 2

Docetaxel or Cabazitaxel With or Without Darolutamide in mCRPC

Recruiting
NCT07723248Phase 3

A Study to Learn About the Investigational Drug Rinzimetostat (ORIC-944) in Patients With mCRPC Who Were Previously Treated With Abiraterone Acetate (Himalayas-1)

Recruiting
NCT04558866Phase 2

Extreme Bipolar Androgen Therapy With Darolutamide and Testosterone Cypionate in Patients With Metastatic Castration-Resistant Prostate Cancer (ExBAT Trial)

Completed
NCT05367440Phase 1

Study of AZD5305 When Given in Combination With New Hormonal Agents in Patients With Metastatic Prostate Cancer

Active Not Recruiting
NCT07611110Phase 3

AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)

Recruiting
NCT07538843

An Observational Study Conducted in China to Evaluate the Efficacy and Safety of Darolutamide in Combination With Androgen Deprivation Therapy (ADT) for Men With Non-metastatic Prostate Cancer That Progressed Following Prior Bicalutamide + ADT Treatment

Recruiting
NCT05050084Phase 3

Two Studies for Patients With Unfavorable Intermediate Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a Higher Gene Risk Score, The Guidance Trial

Active Not Recruiting
NCT05519449Phase 1

Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)

Recruiting
NCT07450599Phase 2

A Study to Learn How Well a Combination of Darolutamide and Androgen Deprivation Therapy (ADT) Works as a Treatment Before Surgery for Men Who Have High-risk Localized Prostate Cancer.

Recruiting
NCT05669664Phase 2

Testing the Anti-cancer Drug Darolutamide in Patients With Testosterone-Driven Salivary Gland Cancers

Active Not Recruiting
NCT06625970Phase 3

Study Evaluating the Efficacy and Safety of Darolutamide and Stereotactic Dose Escalated Radiotherapy in Patients With Localized Prostate Cancer and High-risk Features of Relapse

Recruiting
NCT06120491Phase 3

Saruparib (AZD5305) vs Placebo in Men With Metastatic Castration-Sensitive Prostate Cancer Receiving Physician's Choice New Hormonal Agents

Active Not Recruiting
NCT04484818Phase 3

Testing the Addition of Darolutamide to Hormonal Therapy (Androgen Deprivation Therapy [ADT]) After Surgery for Men With High-Risk Prostate Cancer, The ERADICATE Study

Active Not Recruiting
NCT06169124Phase 2

Study to Test the Drug Darolutamide Along With the Drugs Leuprolide Acetate and Exemestane in Patients With Recurrent Ovarian Granulosa Cell Tumors

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
60