Success Metrics

Clinical Success Rate
90.5%

Based on 19 completed trials

Completion Rate
90%(19/21)
Active Trials
3(12%)
Results Posted
58%(11 trials)
Terminated
2(8%)

Phase Distribution

Ph early_phase_1
1
4%
Ph phase_4
10
38%
Ph phase_3
4
15%
Ph not_applicable
3
12%
Ph phase_1
2
8%
Ph phase_2
6
23%

Phase Distribution

3

Early Stage

6

Mid Stage

14

Late Stage

Phase Distribution26 total trials
Early Phase 1First-in-human
1(3.8%)
Phase 1Safety & dosage
2(7.7%)
Phase 2Efficacy & side effects
6(23.1%)
Phase 3Large-scale testing
4(15.4%)
Phase 4Post-market surveillance
10(38.5%)
N/ANon-phased studies
3(11.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

90.5%

19 of 21 finished

Non-Completion Rate

9.5%

2 ended early

Currently Active

3

trials recruiting

Total Trials

26

all time

Status Distribution
Active(4)
Completed(19)
Terminated(2)
Other(1)

Detailed Status

Completed19
Recruiting2
Terminated2
Active, not recruiting1
unknown1
Not yet recruiting1

Development Timeline

Analytics

Development Status

Total Trials
26
Active
3
Success Rate
90.5%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (3.8%)
Phase 12 (7.7%)
Phase 26 (23.1%)
Phase 34 (15.4%)
Phase 410 (38.5%)
N/A3 (11.5%)

Trials by Status

active_not_recruiting14%
recruiting28%
terminated28%
unknown14%
completed1973%
not_yet_recruiting14%

Recent Activity

3 active trials
Showing 5 of 26
recruitingphase_1

Examining a Novel Gastrointestinal Intervention to Negate Environmental Toxicants (ENGINE)

NCT07226440
recruitingearly_phase_1

Metabolic Effects of Endogenous Bile Acids After Gastric Bypass Surgery

NCT06925997
active_not_recruitingphase_2

Three Antidiarrheal Strategies in HER2+/HR+ Early Breast Cancer Patients Treated With Extended Adjuvant Neratinib

NCT05252988
not_yet_recruitingphase_1

Impact of Therapy Using Colesevelam Treatment Reducing Bile Acids in Patients With Fontan Circulation.

NCT06197763
completedphase_3

A Study of Colesevelam in Fecal Incontinence

NCT02628626
View all 26 trials

Clinical Trials (26)

Showing 20 of 26 trialsScroll for more
NCT07226440Phase 1

Examining a Novel Gastrointestinal Intervention to Negate Environmental Toxicants (ENGINE)

Recruiting
NCT06925997Early Phase 1

Metabolic Effects of Endogenous Bile Acids After Gastric Bypass Surgery

Recruiting
NCT05252988Phase 2

Three Antidiarrheal Strategies in HER2+/HR+ Early Breast Cancer Patients Treated With Extended Adjuvant Neratinib

Active Not Recruiting
NCT06197763Phase 1

Impact of Therapy Using Colesevelam Treatment Reducing Bile Acids in Patients With Fontan Circulation.

Not Yet Recruiting
NCT02628626Phase 3

A Study of Colesevelam in Fecal Incontinence

Completed
NCT00715273Phase 4

Evaluate Carotid Artery Plaque Composition by Magnetic Resonance Imaging in People Receiving Cholesterol Medication

Completed
NCT03955575Phase 4

Treatment of Bile Acid Malabsorption With Liraglutide

Completed
NCT02952963Phase 4

Effect of Bile Acids and Bile Acid Sequstrants on GLP-1 Secretion After Roux-en-Y Gastric Bypass

Completed
NCT02876484Phase 4

Effects of Bile Acids and Bile Acid Sequestrants on GLP-1 Secretion After Roux-en-Y Gastric Bypass

Completed
NCT01948648Not Applicable

Effects of Fish Oil and Colesevelam (STAIR7007)

Unknown
NCT03270085Phase 2

Trial to Understand Efficacy of Colesevelam in Diarrhea Predominant IBS Patients With Bile Acid Malabsorption

Completed
NCT02682680Phase 4

Randomized Trial Comparing Colesevelam vs. Ezetimibe

Completed
NCT00789750Phase 3

Colesevelam as Add-on to Pioglitazone Therapy for Type 2 Diabetes Mellitus

Completed
NCT02619812Phase 2

Manage Diarrhea in Patients With Multiple Myeloma While Receiving Conditioning Chemotherapy for Autologous SCT

Terminated
NCT02111603Phase 4

Ability of Mayo Clinic High-performance Liquid Chromatography (HPLC) Method to Measure Fecal Bile Acids

Completed
NCT01656057Not Applicable

The Impact of Gall Bladder Emptying and Bile Acids on the Human GLP-1-secretion

Completed
NCT02050074Phase 4

The Role of Metformin and Colesevelam in Human GLP-1 Secretion

Completed
NCT00147745Phase 2

Effects of Colesevelam on How the Body Responds to Insulin in Patients With Type 2 Diabetes

Completed
NCT01666223Not Applicable

Effect of Bile Acids on GLP-1 Secretion

Completed
NCT00951899Phase 4

The Effect of Welchol on Glucose Metabolism in Type 2 Diabetics

Completed

Drug Details

Intervention Type
DRUG
Total Trials
26