Success Metrics

Clinical Success Rate
76.1%

Based on 520 completed trials

Completion Rate
76%(520/683)
Active Trials
284(22%)
Results Posted
59%(306 trials)
Terminated
163(13%)

Phase Distribution

Ph phase_2
653
51%
Ph early_phase_1
4
0%
Ph phase_1
287
23%
Ph phase_3
259
20%
Ph phase_4
14
1%
Ph not_applicable
27
2%

Phase Distribution

291

Early Stage

653

Mid Stage

273

Late Stage

Phase Distribution1244 total trials
Early Phase 1First-in-human
4(0.3%)
Phase 1Safety & dosage
287(23.1%)
Phase 2Efficacy & side effects
653(52.5%)
Phase 3Large-scale testing
259(20.8%)
Phase 4Post-market surveillance
14(1.1%)
N/ANon-phased studies
27(2.2%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

71.7%

520 of 725 finished

Non-Completion Rate

28.3%

205 ended early

Currently Active

284

trials recruiting

Total Trials

1,273

all time

Status Distribution
Active(352)
Completed(520)
Terminated(205)
Other(196)

Detailed Status

Completed520
unknown192
Recruiting185
Terminated163
Active, not recruiting99
Not yet recruiting68

Development Timeline

Analytics

Development Status

Total Trials
1273
Active
284
Success Rate
76.1%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (0.3%)
Phase 1287 (23.1%)
Phase 2653 (52.5%)
Phase 3259 (20.8%)
Phase 414 (1.1%)
N/A27 (2.2%)

Trials by Status

completed52041%
unknown19215%
recruiting18515%
active_not_recruiting998%
not_yet_recruiting685%
suspended40%
withdrawn423%
terminated16313%

Recent Activity

Clinical Trials (1,273)

Showing 20 of 1,273 trialsScroll for more
NCT05803382Phase 1

Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers

Recruiting
NCT06901531Phase 3

A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

Recruiting
NCT05568095Phase 3

A Clinical Trial of a New Combination Treatment, Domvanalimab and Zimberelimab, Plus Chemotherapy, for People With an Upper Gastrointestinal Tract Cancer That Cannot be Removed With Surgery That Has Spread to Other Parts of the Body

Active Not Recruiting
NCT07057089Phase 2

Involved-field Radiotherapy-TNT Combined With PD-1 Inhibitor for pMMR Locally Advanced Rectal Cancer (Neo-Field I)

Suspended
NCT07060807Phase 3

A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)

Recruiting
NCT07652242Phase 1

Phase 1 Study of a Self-amplifying RNA Vaccine (ITI-5000) in Stage 2-3 Triple Negative Breast Cancer

Recruiting
NCT07737600Phase 1

A Study of MRG007 Combination Therapy for Advanced Colorectal Cancer

Not Yet Recruiting
NCT05464030Phase 1

Anti-CEACAM5 ADC M9140 in Advanced Solid Tumors (PROCEADE-CRC-01)

Active Not Recruiting
NCT06622057Phase 3

D07001 Softgel-Capsules and Capecitabine Combination Therapy in Patients With Advanced Biliary Tract Cancer

Recruiting
NCT03899155Phase 2

Pan Tumor Rollover Study

Recruiting
NCT07580339Phase 2

Combining DCSZ11 With Radiation and Chemotherapy as Neoadjuvant Treatment for pMMR Locally Advanced Rectal Cancer

Not Yet Recruiting
NCT05009069Phase 2

A Study of Atezolizumab With or Without Tiragolumab Following Neoadjuvant Chemoradiotherapy in Participants With Locally Advanced Rectal Cancer

Active Not Recruiting
NCT06312176Phase 3

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

Recruiting
NCT02595424Phase 2

Cisplatin and Etoposide Versus Temozolomide and Capecitabine in Patients With Advanced Poorly Differentiated (G3) Non-Small Cell Gastrointestinal Neuroendocrine Carcinomas

Active Not Recruiting
NCT06393374Phase 3

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

Recruiting
NCT02445391Phase 3

Platinum in Treating Patients With Residual Triple-Negative Breast Cancer Following Neoadjuvant Chemotherapy

Active Not Recruiting
NCT06966700Phase 3

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

Recruiting
NCT06247995Phase 1

A Phase I/II, Dose Finding and Optimization Study of [177Lu]Lu-NeoB in Combination With Capecitabine in Patients With GRPR+, ER+, HER2- Metastatic Breast Cancer After Progression on Previous Endocrine Therapy in Combination With a CDK4/6 Inhibitor.

Active Not Recruiting
NCT04615013Phase 1

NBTXR3, Chemotherapy, and Radiation Therapy for the Treatment of Esophageal Cancer

Recruiting
NCT03907475Phase 2

Durvalumab in Combination With Chemotherapy in Treating Patients With Advanced Solid Tumors, DURVA+ Trial

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
1,273