Success Metrics

Clinical Success Rate
76.1%

Based on 514 completed trials

Completion Rate
76%(514/675)
Active Trials
263(21%)
Results Posted
59%(304 trials)
Terminated
161(13%)

Phase Distribution

Ph phase_1
285
23%
Ph phase_2
637
51%
Ph phase_4
14
1%
Ph phase_3
249
20%
Ph early_phase_1
4
0%
Ph not_applicable
27
2%

Phase Distribution

289

Early Stage

637

Mid Stage

263

Late Stage

Phase Distribution1216 total trials
Early Phase 1First-in-human
4(0.3%)
Phase 1Safety & dosage
285(23.4%)
Phase 2Efficacy & side effects
637(52.4%)
Phase 3Large-scale testing
249(20.5%)
Phase 4Post-market surveillance
14(1.2%)
N/ANon-phased studies
27(2.2%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

71.7%

514 of 717 finished

Non-Completion Rate

28.3%

203 ended early

Currently Active

263

trials recruiting

Total Trials

1,244

all time

Status Distribution
Active(332)
Completed(514)
Terminated(203)
Other(195)

Detailed Status

Completed514
unknown192
Recruiting166
Terminated161
Active, not recruiting97
Not yet recruiting69

Development Timeline

Analytics

Development Status

Total Trials
1244
Active
263
Success Rate
76.1%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (0.3%)
Phase 1285 (23.4%)
Phase 2637 (52.4%)
Phase 3249 (20.5%)
Phase 414 (1.2%)
N/A27 (2.2%)

Trials by Status

recruiting16613%
withdrawn423%
active_not_recruiting978%
terminated16113%
not_yet_recruiting696%
completed51441%
suspended30%
unknown19215%

Recent Activity

Clinical Trials (1,244)

Showing 20 of 1,244 trialsScroll for more
NCT03377387Phase 1

Capecitabine 7/7 Schedule With Neratinib in Patients With Metastatic HER2-Positive Breast Cancer

Active Not Recruiting
NCT04661150Phase 2

A Study of Atezolizumab and Trastuzumab in Combination With Capecitabine and Oxaliplatin in Patients With HER2 Positive Locally Advanced Resectable Gastric Cancer of Adenocarcinoma of Gastroesophageal Junction

Active Not Recruiting
NCT07043400Phase 3

A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy in Patients With Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

Recruiting
NCT07490262Phase 2

A Study to Evaluate the Efficacy and Safety of IBI310 and Sintilimab Combination Therapy in Patients With Hepatocellular Carcinoma as First-line Treatment.

Recruiting
NCT07060807Phase 3

A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)

Recruiting
NCT04615013Phase 1

NBTXR3, Chemotherapy, and Radiation Therapy for the Treatment of Esophageal Cancer

Recruiting
NCT06741644Phase 1

A Phase I/II Study of CS2009 in Participants With Advanced Solid Tumors

Recruiting
NCT03161522Phase 2

Chemotherapy With or Without Radiation or Surgery in Treating Participants With Oligometastatic Esophageal or Gastric Cancer

Recruiting
NCT05251948Phase 1

An Umbrella Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Gastric or Gastroesophageal Junction Carcinoma

Terminated
NCT06324357Phase 1

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

Recruiting
NCT03451370

First-line Combination of Capecitabine and Oxaliplatin Plus Bevacizumab in Elderly Patients With Metastatic Colorectal Cancer

Active Not Recruiting
NCT07529613Phase 1

Trastuzumab Deruxtecan Plus Nivolumab Plus Capecitabine Plus Oxaliplatin for HER2 Low Gastric and Gastroesophageal Junction Adenocarcinoma

Completed
NCT06622057Phase 3

D07001 Softgel-Capsules and Capecitabine Combination Therapy in Patients With Advanced Biliary Tract Cancer

Not Yet Recruiting
NCT06205485Phase 3

Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer

Recruiting
NCT05821556Phase 2

Valproic Acid/Simvastatin Plus Gemcitabine/Nab-paclitaxel Based Regimens in Untreated Metastatic Pancreatic Adenocarcinoma Patients

Recruiting
NCT04929028Phase 2

Therapy Adapted for High Risk and Low Risk HIV-Associated Anal Cancer

Active Not Recruiting
NCT06966700Phase 3

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

Recruiting
NCT06417476Phase 2

Short-course Radiotherapy or Long-course Chemoradiation Followed by mFOLFOXIRI Consolidation Chemotherapy for Organ Preservation in Low Rectal Cancer

Active Not Recruiting
NCT06393374Phase 3

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

Recruiting
NCT07007559Phase 2

ASPEN-09-03: A Study of Evorpacept in Combination With Trastuzumab and Chemotherapy in Metastatic HER2-Positive Breast Cancer

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
1,244