Success Metrics

Clinical Success Rate
76.2%

Based on 522 completed trials

Completion Rate
76%(522/685)
Active Trials
284(22%)
Results Posted
59%(307 trials)
Terminated
163(13%)

Phase Distribution

Ph not_applicable
27
2%
Ph phase_4
14
1%
Ph phase_1
288
23%
Ph phase_2
653
51%
Ph phase_3
259
20%
Ph early_phase_1
4
0%

Phase Distribution

292

Early Stage

653

Mid Stage

273

Late Stage

Phase Distribution1245 total trials
Early Phase 1First-in-human
4(0.3%)
Phase 1Safety & dosage
288(23.1%)
Phase 2Efficacy & side effects
653(52.4%)
Phase 3Large-scale testing
259(20.8%)
Phase 4Post-market surveillance
14(1.1%)
N/ANon-phased studies
27(2.2%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

71.8%

522 of 727 finished

Non-Completion Rate

28.2%

205 ended early

Currently Active

284

trials recruiting

Total Trials

1,274

all time

Status Distribution
Active(352)
Completed(522)
Terminated(205)
Other(195)

Detailed Status

Completed522
unknown191
Recruiting184
Terminated163
Active, not recruiting100
Not yet recruiting68

Development Timeline

Analytics

Development Status

Total Trials
1274
Active
284
Success Rate
76.2%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (0.3%)
Phase 1288 (23.1%)
Phase 2653 (52.4%)
Phase 3259 (20.8%)
Phase 414 (1.1%)
N/A27 (2.2%)

Trials by Status

not_yet_recruiting685%
active_not_recruiting1008%
suspended40%
withdrawn423%
terminated16313%
unknown19115%
completed52241%
recruiting18414%

Recent Activity

Clinical Trials (1,274)

Showing 20 of 1,274 trialsScroll for more
NCT06926868Phase 2

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

Recruiting
NCT07043400Phase 3

A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy in Patients With Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

Recruiting
NCT06966700Phase 3

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

Recruiting
NCT07060807Phase 3

A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)

Recruiting
NCT06393374Phase 3

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

Recruiting
NCT06469944Phase 1

Substudy 06C: A Study of Investigational Agents With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)

Recruiting
NCT05502393Phase 1

A Clinical Study to Evaluate the Safety and Tolerability of JS107 in Advanced or Metastatic Solid Tumors

Active Not Recruiting
NCT06324357Phase 1

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

Recruiting
NCT07413939Phase 2

RO7771950 Versus Tucatinib in Combination With Trastuzumab and Capecitabine in People With Locally Advanced or Metastatic Breast Cancer That is Human Epidermal Growth Factor Receptor 2 (HER2)-Positive

Recruiting
NCT01494155Phase 2

Short Course Radiation Therapy With Proton or Photon Beam Capecitabine and Hydroxychloroquine for Resectable Pancreatic Cancer

Completed
NCT07737600Phase 1

A Study of MRG007 Combination Therapy for Advanced Colorectal Cancer

Not Yet Recruiting
NCT04556773Phase 1

A Phase 1b Study of T-DXd Combinations in HER2-low Advanced or Metastatic Breast Cancer

Active Not Recruiting
NCT06210971Phase 2

Neoadjuvant Chemoradiation With Nal-IRI and Capecitabine Guided by UGT1A1 Status in Patients With Rectal Cancer

Active Not Recruiting
NCT07652242Phase 1

Phase 1 Study of a Self-amplifying RNA Vaccine (ITI-5000) in Stage 2-3 Triple Negative Breast Cancer

Recruiting
NCT06281886Phase 2

Induction Immuno-chemotherapy and Concurrent Chemoradiotherapy With or Without Apatinib in Unresectable, Locally Advanced Esophageal Squamous Cell Carcinoma

Completed
NCT06949111Phase 2

Radiotherapy + Systemic Therapy as Conversion Therapy for pMMR/MSS T4M0 Colon Cancer(Neo-Color)

Recruiting
NCT05803382Phase 1

Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers

Recruiting
NCT05568095Phase 3

A Clinical Trial of a New Combination Treatment, Domvanalimab and Zimberelimab, Plus Chemotherapy, for People With an Upper Gastrointestinal Tract Cancer That Cannot be Removed With Surgery That Has Spread to Other Parts of the Body

Active Not Recruiting
NCT07057089Phase 2

Involved-field Radiotherapy-TNT Combined With PD-1 Inhibitor for pMMR Locally Advanced Rectal Cancer (Neo-Field I)

Suspended
NCT06901531Phase 3

A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
1,274