Success Metrics

Clinical Success Rate
76.0%

Based on 517 completed trials

Completion Rate
76%(517/680)
Active Trials
278(22%)
Results Posted
59%(305 trials)
Terminated
163(13%)

Phase Distribution

Ph phase_4
14
1%
Ph early_phase_1
4
0%
Ph not_applicable
27
2%
Ph phase_1
286
23%
Ph phase_2
648
51%
Ph phase_3
253
20%

Phase Distribution

290

Early Stage

648

Mid Stage

267

Late Stage

Phase Distribution1232 total trials
Early Phase 1First-in-human
4(0.3%)
Phase 1Safety & dosage
286(23.2%)
Phase 2Efficacy & side effects
648(52.6%)
Phase 3Large-scale testing
253(20.5%)
Phase 4Post-market surveillance
14(1.1%)
N/ANon-phased studies
27(2.2%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

71.6%

517 of 722 finished

Non-Completion Rate

28.4%

205 ended early

Currently Active

278

trials recruiting

Total Trials

1,261

all time

Status Distribution
Active(344)
Completed(517)
Terminated(205)
Other(195)

Detailed Status

Completed517
unknown192
Recruiting182
Terminated163
Active, not recruiting96
Not yet recruiting66

Development Timeline

Analytics

Development Status

Total Trials
1261
Active
278
Success Rate
76.0%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (0.3%)
Phase 1286 (23.2%)
Phase 2648 (52.6%)
Phase 3253 (20.5%)
Phase 414 (1.1%)
N/A27 (2.2%)

Trials by Status

withdrawn423%
suspended30%
completed51741%
recruiting18214%
unknown19215%
not_yet_recruiting665%
terminated16313%
active_not_recruiting968%

Recent Activity

Clinical Trials (1,261)

Showing 20 of 1,261 trialsScroll for more
NCT07222215Phase 2

PhII Randomized CAPecitabine + ELAcestrant vs. Capecitabine Alone in ER+ Breast Cancer (CAPELA)

Recruiting
NCT06966700Phase 3

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

Recruiting
NCT03907475Phase 2

Durvalumab in Combination With Chemotherapy in Treating Patients With Advanced Solid Tumors, DURVA+ Trial

Recruiting
NCT04607421Phase 3

A Study of Encorafenib Plus Cetuximab With or Without Chemotherapy in People With Previously Untreated Metastatic Colorectal Cancer

Active Not Recruiting
NCT05803382Phase 1

Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers

Recruiting
NCT06622057Phase 3

D07001 Softgel-Capsules and Capecitabine Combination Therapy in Patients With Advanced Biliary Tract Cancer

Recruiting
NCT04379596Phase 2

Ph1b/2 Study of the Safety and Efficacy of T-DXd Combinations in Advanced HER2-expressing Gastric Cancer (DESTINY-Gastric03)

Recruiting
NCT07631052Phase 2

Capecitabine in ER+/HER2-negative Breast Cancer

Recruiting
NCT06884670Phase 2

Assessment of Efficacy and Safety of PD-1 Monoclonal Antibody Combined With IL-2 and CapeOX in Neoadjuvant Therapy for Locally Advanced Rectal Cancer Prior to Surgery: A Prospective, Multi-center, Randomized Controlled Study

Completed
NCT05365581Phase 1

A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer

Recruiting
NCT06247995Phase 1

A Phase I/II, Dose Finding and Optimization Study of [177Lu]Lu-NeoB in Combination With Capecitabine in Patients With GRPR+, ER+, HER2- Metastatic Breast Cancer After Progression on Previous Endocrine Therapy in Combination With a CDK4/6 Inhibitor.

Recruiting
NCT07413939Phase 2

RO7771950 Versus Tucatinib in Combination With Trastuzumab and Capecitabine in People With Locally Advanced or Metastatic Breast Cancer That is Human Epidermal Growth Factor Receptor 2 (HER2)-Positive

Recruiting
NCT06926868Phase 2

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

Recruiting
NCT05633654Phase 3

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)

Recruiting
NCT06205485Phase 3

Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer

Recruiting
NCT07060807Phase 3

A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)

Recruiting
NCT06393374Phase 3

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

Recruiting
NCT06312176Phase 3

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

Recruiting
NCT07007559Phase 2

ASPEN-09-03: A Study of Evorpacept in Combination With Trastuzumab and Chemotherapy in Metastatic HER2-Positive Breast Cancer

Recruiting
NCT06901531Phase 3

A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
1,261