Success Metrics

Clinical Success Rate
66.7%

Based on 30 completed trials

Completion Rate
67%(30/45)
Active Trials
9(15%)
Results Posted
100%(30 trials)
Terminated
15(25%)

Phase Distribution

Ph early_phase_1
1
2%
Ph phase_1
6
10%
Ph phase_3
18
30%
Ph phase_2
34
57%

Phase Distribution

7

Early Stage

34

Mid Stage

18

Late Stage

Phase Distribution59 total trials
Early Phase 1First-in-human
1(1.7%)
Phase 1Safety & dosage
6(10.2%)
Phase 2Efficacy & side effects
34(57.6%)
Phase 3Large-scale testing
18(30.5%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

63.8%

30 of 47 finished

Non-Completion Rate

36.2%

17 ended early

Currently Active

9

trials recruiting

Total Trials

60

all time

Status Distribution
Active(10)
Completed(30)
Terminated(17)
Other(3)

Detailed Status

Completed30
Terminated15
Recruiting5
Active, not recruiting4
unknown3
Withdrawn2

Development Timeline

Analytics

Development Status

Total Trials
60
Active
9
Success Rate
66.7%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (1.7%)
Phase 16 (10.2%)
Phase 234 (57.6%)
Phase 318 (30.5%)

Trials by Status

not_yet_recruiting12%
terminated1525%
withdrawn23%
recruiting58%
unknown35%
active_not_recruiting47%
completed3050%

Recent Activity

Clinical Trials (60)

Showing 20 of 60 trialsScroll for more
NCT05467800Phase 2

Study of Canakinumab in Patients With Myelofibrosis

Active Not Recruiting
NCT04789681Phase 2

Canakinumab for the Prevention of Lung Cancer, the Can-Prevent-Lung Trial

Recruiting
NCT04028245Early Phase 1

A Study of Combination Spartalizumab and Canakinumab in Patients With Localized Clear Cell Renal Cell Carcinoma

Completed
NCT04239157Phase 2

A Phase II, Open-Label, Study of Subcutaneous Canakinumab, an Anti-IL-1β Human Monoclonal Antibody, for Patients With Low or Int-1 Risk IPSS/IPSS-R Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia

Recruiting
NCT04717635Phase 3

Study of Efficacy and Safety of Canakinumab in Japanese Patients With AOSD

Completed
NCT05984602Phase 1

A Phase IB Study to Determine the Safety and Tolerability of Canakinumab and Tislelizumab in Combination With Nab-Paclitaxel and Gemcitabine in the Neo-adjuvant Treatment of Patients With Pancreatic Cancer

Active Not Recruiting
NCT03631199Phase 3

Study of Efficacy and Safety of Pembrolizumab Plus Platinum-based Doublet Chemotherapy With or Without Canakinumab in Previously Untreated Locally Advanced or Metastatic Non-squamous and Squamous NSCLC Subjects

Terminated
NCT06038526Phase 2

Evaluation of Canakinumab in High-Risk Former-Smokers

Active Not Recruiting
NCT05641831Phase 2

Canakinumab for the Prevention of Progression to Cancer in Patients With Clonal Cytopenias of Unknown Significance, IMPACT Study

Recruiting
NCT05535738Phase 2

Using a Contact Dermatitis Model With Biologic Medications to Study Skin Inflammation

Recruiting
NCT04814368Phase 2

A Safety and Efficacy Study of Anti-inflammatory (Canakinumab) and Cartilage Stimulating (LNA043) Drugs Injected Into the Knee Joint of Participants With Knee Osteoarthritis (OA)

Terminated
NCT04795466Phase 2

Study of the Efficacy and Safety of Various Anti-inflammatory Agents in Participants With Mild Cognitive Impairment or Mild Alzheimer's Disease

Terminated
NCT04810611Phase 1

Phase Ib Study of Select Drug Combinations in Patients With Lower Risk MDS

Terminated
NCT07138898Phase 2

Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder Arthroplasty

Not Yet Recruiting
NCT04905316Phase 2

A Study of Canakinumab With Chemotherapy, Radiation Therapy, and Durvalumab in People With Lung Cancer

Active Not Recruiting
NCT03742349Phase 1

Study of Safety and Efficacy of Novel Immunotherapy Combinations in Patients With Triple Negative Breast Cancer (TNBC).

Terminated
NCT05401578Phase 3

Canakinumab for the Treatment of Postprandial Hypoglycemia

Recruiting
NCT03447769Phase 3

Brief Title: Study of Efficacy and Safety of Canakinumab as Adjuvant Therapy in Adult Subjects With Stages AJCC/UICC v. 8 II-IIIA and IIIB (T>5cm N2) Completely Resected Non-small Cell Lung Cancer Acronym: CANOPY-A

Terminated
NCT03968419Phase 2

This Study Will Evaluate the Effect of Canakinumab or Pembrolizumab Given as Monotherapy or in Combination as Neo-adjuvant Treatment for Subjects With Early Stages NSCLC.

Terminated
NCT03626545Phase 3

Phase III Study Evaluating Efficacy and Safety of Canakinumab in Combination With Docetaxel in Adult Subjects With Non-small Cell Lung Cancers as a Second or Third Line Therapy

Terminated

Drug Details

Intervention Type
DRUG
Total Trials
60