Success Metrics

Clinical Success Rate
83.3%

Based on 10 completed trials

Completion Rate
83%(10/12)
Active Trials
3(11%)
Results Posted
50%(5 trials)
Terminated
2(7%)

Phase Distribution

Ph early_phase_1
2
7%
Ph not_applicable
4
15%
Ph phase_4
3
11%
Ph phase_2
8
30%
Ph phase_1
5
19%
Ph phase_3
3
11%

Phase Distribution

7

Early Stage

8

Mid Stage

6

Late Stage

Phase Distribution25 total trials
Early Phase 1First-in-human
2(8.0%)
Phase 1Safety & dosage
5(20.0%)
Phase 2Efficacy & side effects
8(32.0%)
Phase 3Large-scale testing
3(12.0%)
Phase 4Post-market surveillance
3(12.0%)
N/ANon-phased studies
4(16.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

66.7%

10 of 15 finished

Non-Completion Rate

33.3%

5 ended early

Currently Active

3

trials recruiting

Total Trials

27

all time

Status Distribution
Active(8)
Completed(10)
Terminated(5)
Other(4)

Detailed Status

Completed10
Not yet recruiting5
unknown4
Withdrawn3
Recruiting2
Terminated2

Development Timeline

Analytics

Development Status

Total Trials
27
Active
3
Success Rate
83.3%
Most Advanced
Phase 4

Trials by Phase

Early Phase 12 (8.0%)
Phase 15 (20.0%)
Phase 28 (32.0%)
Phase 33 (12.0%)
Phase 43 (12.0%)
N/A4 (16.0%)

Trials by Status

recruiting27%
active_not_recruiting14%
terminated27%
completed1037%
withdrawn311%
unknown415%
not_yet_recruiting519%

Recent Activity

Clinical Trials (27)

Showing 20 of 27 trialsScroll for more
NCT07570121Phase 1

Pharmacokinetics and Placental Transfer of Caffeine

Not Yet Recruiting
NCT07216365Phase 2

Caffeine Optimization for Oxygen Saturation Index in ELBW Infants

Not Yet Recruiting
NCT05574400Phase 2

The Caffeine, Postoperative Delirium, and Change in Outcomes After Surgery (CAPACHINOS-2) Study

Active Not Recruiting
NCT07262060Phase 2

Improving Preterm Kidney Outcomes With Caffeine

Not Yet Recruiting
NCT06972108Phase 2

CAffeine Use in Prolonged Oxygen Use in meConium aspIration Syndrome in Neonatal Outcomes (CAPUCINO)

Not Yet Recruiting
NCT06821698Phase 1

To Determine the Effect of KP-001 on Rosuvastatin, Caffeine PK and the Effect of Fluvoxamine on KP-001 PK in Volunteers

Completed
NCT06026163Phase 2

Caffeine as an Adjuvant Therapy for Late Preterm Infants With Respiratory Distress

Recruiting
NCT06972849Not Applicable

Caffeine Citrate to Improve Neonatal Outcomes.

Not Yet Recruiting
NCT03340727Phase 3

Moderately Preterm Infants With Caffeine at Home for Apnea (MoCHA) Trial

Terminated
NCT05295784Phase 1

PK and Safety of Caffeine in Neonates With Hypoxic Ischemic Encephalopathy Receiving Therapeutic Hypothermia

Withdrawn
NCT06401083Phase 4

The Effect of an Additional Pre-extubational Loading Dose of Caffeine-citrate

Recruiting
NCT05393817

Caffeine Citrate Use and Electronic Activity of the Diaphragm (EDI) Changes

Completed
NCT06097767Early Phase 1

the Incidence of Necrotizing Enterocolitis in Preterm With Respiratory Distress Syndrome Undergoing Caffeine Therapy

Unknown
NCT04044976Not Applicable

Caffeine Treatment in in the Delivery Room

Completed
NCT03577730Early Phase 1

Caffeine and Neurologic Recovery Following Surgery and General Anesthesia

Completed
NCT03086473Phase 4

Early Caffeine in Preterm Neonates

Unknown
NCT04483492

Direct Effect of Caffeine on Diaphragmatic Muscles

Unknown
NCT02344225Phase 2

Synergistic Pharmacologic Intervention for Prevention of ROP (SPIPROP Study)

Completed
NCT03097900Phase 2

Does Caffeine Enhance Bowel Recovery After Colorectal Surgery?

Completed
NCT04144712Phase 1

Caffeine as Respiratory Stimulant in Preterm Infants

Unknown

Drug Details

Intervention Type
DRUG
Total Trials
27