Success Metrics

Clinical Success Rate
84.6%

Based on 11 completed trials

Completion Rate
85%(11/13)
Active Trials
24(62%)
Results Posted
200%(22 trials)
Terminated
2(5%)

Phase Distribution

Ph phase_2
28
72%
Ph phase_1
9
23%
Ph phase_3
2
5%

Phase Distribution

9

Early Stage

28

Mid Stage

2

Late Stage

Phase Distribution39 total trials
Phase 1Safety & dosage
9(23.1%)
Phase 2Efficacy & side effects
28(71.8%)
Phase 3Large-scale testing
2(5.1%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

78.6%

11 of 14 finished

Non-Completion Rate

21.4%

3 ended early

Currently Active

24

trials recruiting

Total Trials

39

all time

Status Distribution
Active(24)
Completed(11)
Terminated(3)
Other(1)

Detailed Status

Active, not recruiting16
Completed11
Recruiting8
Terminated2
Withdrawn1
Suspended1

Development Timeline

Analytics

Development Status

Total Trials
39
Active
24
Success Rate
84.6%
Most Advanced
Phase 3

Trials by Phase

Phase 19 (23.1%)
Phase 228 (71.8%)
Phase 32 (5.1%)

Trials by Status

withdrawn13%
terminated25%
active_not_recruiting1641%
completed1128%
recruiting821%
suspended13%

Recent Activity

Clinical Trials (39)

Showing 20 of 39 trialsScroll for more
NCT05691478Phase 2

A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

Recruiting
NCT04079712Phase 2

Testing the Combination of XL184 (Cabozantinib), Nivolumab, and Ipilimumab for Poorly Differentiated Neuroendocrine Tumors

Active Not Recruiting
NCT05111574Phase 2

Using Nivolumab Alone or With Cabozantinib to Prevent Mucosal Melanoma Return After Surgery

Active Not Recruiting
NCT04339738Phase 2

Testing the Addition of Nivolumab to Chemotherapy in Treatment of Soft Tissue Sarcoma

Active Not Recruiting
NCT06811116Phase 1

Testing the Addition of an Anti-cancer Drug, Sapanisertib, to the Usual Chemotherapy Treatment (Cabozantinib) in Metastatic Liver Cell Cancer With a Change in Genes for the Protein β-Catenin, The SAPHIRE Trial

Recruiting
NCT05136196Phase 2

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Recruiting
NCT04071223Phase 2

Testing the Addition of a New Anti-cancer Drug, Radium-223 Dichloride, to the Usual Treatment (Cabozantinib) for Advanced Renal Cell Cancer That Has Spread to the Bone, RadiCaL Study

Active Not Recruiting
NCT03914300Phase 2

Testing the Combination of Cabozantinib, Nivolumab, and Ipilimumab (CaboNivoIpi) for Advanced Differentiated Thyroid Cancer

Active Not Recruiting
NCT03866382Phase 2

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

Recruiting
NCT02867592Phase 2

Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors

Active Not Recruiting
NCT04310007Phase 2

Testing the Addition of the Pill Chemotherapy, Cabozantinib, to the Standard Immune Therapy Nivolumab Compared to Standard Chemotherapy for Non-small Cell Lung Cancer

Active Not Recruiting
NCT05092373Phase 1

Phase I Study of Tumor Treating Fields (TTF) in Combination With Cabozantinib or With Pembrolizumab and Nab-Paclitaxel in Patients With Advanced Solid Tumors Involving the Abdomen or Thorax

Recruiting
NCT03375320Phase 3

Testing Cabozantinib in Patients With Advanced Pancreatic Neuroendocrine and Carcinoid Tumors

Active Not Recruiting
NCT01708954Phase 2

Erlotinib Hydrochloride and Cabozantinib-s-Malate Alone or in Combination as Second or Third Line Therapy in Treating Patients With Stage IV Non-small Cell Lung Cancer

Active Not Recruiting
NCT05904080Phase 2

Testing Nivolumab and Ipilimumab Immunotherapy With or Without the Targeted Drug Cabozantinib in Recurrent, Metastatic, or Incurable Nasopharyngeal Cancer

Suspended
NCT05092958Phase 3

Testing the Addition of the Anti-cancer Drug, Cabozantinib, to the Usual Immunotherapy Treatment, Avelumab, in Patients With Metastatic Urothelial Cancer, MAIN-CAV Study

Active Not Recruiting
NCT02243605Phase 2

Cabozantinib S-malate in Treating Patients With Relapsed Osteosarcoma or Ewing Sarcoma

Active Not Recruiting
NCT05168618Phase 2

Cabozantinib and Atezolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer

Recruiting
NCT03367741Phase 2

Cabozantinib S-malate and Nivolumab in Treating Patients With Advanced, Recurrent, or Metastatic Endometrial Cancer

Active Not Recruiting
NCT04514484Phase 1

Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
39