Success Metrics

Clinical Success Rate
91.7%

Based on 22 completed trials

Completion Rate
92%(22/24)
Active Trials
1(3%)
Results Posted
91%(20 trials)
Terminated
2(7%)

Phase Distribution

Ph phase_3
10
34%
Ph phase_4
10
34%
Ph phase_1
1
3%
Ph phase_2
8
28%

Phase Distribution

1

Early Stage

8

Mid Stage

20

Late Stage

Phase Distribution29 total trials
Phase 1Safety & dosage
1(3.4%)
Phase 2Efficacy & side effects
8(27.6%)
Phase 3Large-scale testing
10(34.5%)
Phase 4Post-market surveillance
10(34.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

81.5%

22 of 27 finished

Non-Completion Rate

18.5%

5 ended early

Currently Active

1

trials recruiting

Total Trials

29

all time

Status Distribution
Active(1)
Completed(22)
Terminated(5)
Other(1)

Detailed Status

Completed22
Withdrawn3
Terminated2
unknown1
Recruiting1

Development Timeline

Analytics

Development Status

Total Trials
29
Active
1
Success Rate
91.7%
Most Advanced
Phase 4

Trials by Phase

Phase 11 (3.4%)
Phase 28 (27.6%)
Phase 310 (34.5%)
Phase 410 (34.5%)

Trials by Status

terminated27%
unknown13%
withdrawn310%
recruiting13%
completed2276%

Recent Activity

Clinical Trials (29)

Showing 20 of 29 trialsScroll for more
NCT03295721Phase 3

Bunionectomy Study for Postoperative Analgesia (EPOCH 1)

Completed
NCT03237481Phase 3

Phase 3 Herniorrhaphy Study for Postoperative Analgesia (EPOCH 2)

Completed
NCT03974932Phase 3

Total Knee Arthroplasty (TKA) Study of HTX-011 in an Multimodal Analgesic Regimen (MMA) Regimen

Completed
NCT02762929Phase 2

Evaluation of the Efficacy and Safety of Locally Administered HTX-011 for Postoperative Analgesia Following Bunionectomy

Completed
NCT05157841Phase 3

Phase 3, Sciatic Nerve Block With EXPAREL for Subjects Undergoing Bunionectomy

Completed
NCT05224089Phase 4

Bilateral TAP and RS Blocks Using Liposomal Bupivacaine/Bupivacaine vs. Regular Bupivacaine in Laparoscopic Colectomy

Recruiting
NCT05005260Phase 4

Liposomal Bupivacaine Single-Injection Interscalene Block vs. Continuous Interscalene Block for Primary Total Shoulder Arthroplasty

Completed
NCT04232306Phase 4

Liposomal Bupivacaine + Bupivacaine vs. Bupivacaine Alone on Opioid Use After Elective c/Section

Withdrawn
NCT03922048Phase 2

Pediatric Postoperative Analgesia Herniorrhaphy Study

Withdrawn
NCT00485693Phase 2

Dose-Ranging Study for Prolonged Postoperative Analgesia in Subject Undergoing Total Knee Arthroplasty

Completed
NCT03359811Phase 3

Four Quadrants Transverse Abdominus Plane (4Q-TAP) Block With Plain and Liposomal Bupivacaine vs. Thoracic Epidermal Analgesia (TEA) in Patients Undergoing Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy (CRS-HIPEC) on an Enhanced Recovery Pathway

Completed
NCT04398329Phase 1

Dose-Escalation Study of HTX-034 Following Bunionectomy

Completed
NCT03015961Phase 4

Phase 4, Controlled Study in Adult Subjects Undergoing Primary, 1-2 Level, Open Lumbar Spinal Fusion Surgery

Terminated
NCT02574520Phase 3

Trial of Extended Release Bupivacaine for Pain Relief After Surgery

Completed
NCT01052012Phase 3

Bupivacaine Effectiveness and Safety in SABER® Trial

Completed
NCT00529126Phase 2

Phase 2 Dose-Ranging Study of SKY0402 for Prolonged Postoperative Analgesia in Subject Undergoing Hemorrhoidectomy

Completed
NCT00485433Phase 2

Dose-ranging Study for Postoperative Analgesia in Subjects Undergoing Primary Unilateral Inguinal Hernia Repair

Completed
NCT04751344Phase 4

Liposomal Bupivacaine Versus Bupivacaine Plain for Operative Pain Management of Forefoot Surgery

Unknown
NCT01206595Phase 2

Safety, Efficacy, and Pharmacokinetics of SKY0402 Administered as a Nerve Block in Subjects Undergoing Bunionectomy

Completed
NCT01203644Phase 2

Evaluation of the Safety, Efficacy, and Pharmacokinetics of SKY0402 in Subjects Undergoing Inguinal Hernia Repair

Completed

Drug Details

Intervention Type
DRUG
Total Trials
29