Success Metrics

Clinical Success Rate
73.3%

Based on 11 completed trials

Completion Rate
73%(11/15)
Active Trials
9(26%)
Results Posted
118%(13 trials)
Terminated
4(12%)

Phase Distribution

Ph phase_1
8
24%
Ph phase_3
2
6%
Ph phase_2
17
50%

Phase Distribution

8

Early Stage

17

Mid Stage

2

Late Stage

Phase Distribution27 total trials
Phase 1Safety & dosage
8(29.6%)
Phase 2Efficacy & side effects
17(63.0%)
Phase 3Large-scale testing
2(7.4%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

55.0%

11 of 20 finished

Non-Completion Rate

45.0%

9 ended early

Currently Active

9

trials recruiting

Total Trials

34

all time

Status Distribution
Active(10)
Completed(11)
Terminated(9)
Other(4)

Detailed Status

Completed11
Active, not recruiting5
Withdrawn5
unknown4
Terminated4
Recruiting4

Development Timeline

Analytics

Development Status

Total Trials
34
Active
9
Success Rate
73.3%
Most Advanced
Phase 3

Trials by Phase

Phase 18 (29.6%)
Phase 217 (63.0%)
Phase 32 (7.4%)

Trials by Status

not_yet_recruiting13%
active_not_recruiting515%
unknown412%
terminated412%
withdrawn515%
completed1132%
recruiting412%

Recent Activity

Clinical Trials (34)

Showing 20 of 34 trialsScroll for more
NCT04374305Phase 2

Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis (INTUITT-NF2)

Recruiting
NCT03737994Phase 2

Targeted Treatment for ALK Positive Patients Who Have Previously Been Treated for Non-squamous Non-small Cell Lung Cancer

Terminated
NCT05100069

Survey of Brigatinib Used To Treat People With Non-Small Cell Lung Cancer

Recruiting
NCT04318938Phase 2

Advancing Brigatinib Properties in ALK+ NSCLC Patients by Deep Phenotyping

Active Not Recruiting
NCT05721950

A Study to Learn About Brigatinib Treatment Information Available in Chinese Participants With Non-Small-cell Lung Cancer (NSCLC)

Active Not Recruiting
NCT04223596Phase 2

Clinical Utility of Liquid Biopsy in Brigatinib ALK+ Patients

Active Not Recruiting
NCT04925609Phase 1

Brigatinib in Pediatric and Young Adult Patients With ALK+ ALCL, IMT or Other Solid Tumors

Recruiting
NCT03707938Phase 1

Local Consolidative Therapy and Brigatinib in Treating Patients With Stage IV or Recurrent Non-small Cell Lung Cancer

Active Not Recruiting
NCT04227028Phase 1

Brigatinib and Bevacizumab for the Treatment of ALK-Rearranged Locally Advanced, Metastatic, or Recurrent NSCLC

Active Not Recruiting
NCT03596866Phase 3

A Study of Brigatinib Compared to Alectinib in Adults With Non-Small-Cell Lung Cancer

Completed
NCT03535740Phase 2

A Study of Brigatinib in Participants With Anaplastic Lymphoma Kinase-Positive (ALK+), Advanced Non-Small-Cell Lung Cancer (NSCLC) Progressed on Alectinib or Ceritinib

Completed
NCT06522360Phase 2

Brigatinib Plus Chemotherapy or Local Consolidation Therapy in ALK Positive Advanced Non-small Cell Lung Cancer (BrightStar-2)

Withdrawn
NCT05834348

A Study to Learn About the Effectiveness of Cancer Medicines in Patients With Metastatic Non-small Cell Lung Cancer in Norway.

Completed
NCT06813079Phase 2

Using Tumor Models to Determine Treatments

Not Yet Recruiting
NCT06132867Phase 1

A Study to Compare the Relative Bioavailability of Brigatinib When Swallowed as a Solution Versus When Swallowed as a Tablet in Healthy Adults

Completed
NCT05718297Phase 2

Brigatinib Post Definitive Chemo-radiotherapy in Patients with ALK-fusion Non-small Cell Lung Cancer

Withdrawn
NCT06532149

ERectile Dysfunctions, gOnadotoxicity and Sexual Health Assessment in Men With Lung Cancer

Recruiting
NCT03546894

A Study to Determine Progression-free Survival (PFS) and Evaluate Participant Experience for Participants With Metastatic Anaplastic Lymphoma Kinase-positive (ALK+) Non-Small Cell Lung Cancer (NSCLC) Treated With Anaplastic Lymphoma Kinase (ALK) Inhibitors

Completed
NCT03410108Phase 2

Phase 2 Study of Brigatinib in Japanese Participants With Anaplastic Lymphoma Kinase (ALK)-Positive Non-Small Cell Lung Cancer (NSCLC)

Completed
NCT04591431Phase 2

The Rome Trial From Histology to Target: the Road to Personalize Target Therapy and Immunotherapy

Unknown

Drug Details

Intervention Type
DRUG
Total Trials
34