Success Metrics

Clinical Success Rate
48.0%

Based on 12 completed trials

Completion Rate
48%(12/25)
Active Trials
161(70%)
Results Posted
250%(30 trials)
Terminated
13(6%)

Phase Distribution

Ph phase_3
19
8%
Ph not_applicable
3
1%
Ph phase_2
111
48%
Ph early_phase_1
2
1%
Ph phase_1
92
40%

Phase Distribution

94

Early Stage

111

Mid Stage

19

Late Stage

Phase Distribution227 total trials
Early Phase 1First-in-human
2(0.9%)
Phase 1Safety & dosage
92(40.5%)
Phase 2Efficacy & side effects
111(48.9%)
Phase 3Large-scale testing
19(8.4%)
N/ANon-phased studies
3(1.3%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

32.4%

12 of 37 finished

Non-Completion Rate

67.6%

25 ended early

Currently Active

161

trials recruiting

Total Trials

229

all time

Status Distribution
Active(185)
Completed(12)
Terminated(25)
Other(7)

Detailed Status

Recruiting115
Active, not recruiting46
Not yet recruiting24
Terminated13
Completed12
Withdrawn12

Development Timeline

Analytics

Development Status

Total Trials
229
Active
161
Success Rate
48.0%
Most Advanced
Phase 3

Trials by Phase

Early Phase 12 (0.9%)
Phase 192 (40.5%)
Phase 2111 (48.9%)
Phase 319 (8.4%)
N/A3 (1.3%)

Trials by Status

active_not_recruiting4620%
completed125%
not_yet_recruiting2410%
terminated136%
recruiting11550%
withdrawn125%
suspended73%

Recent Activity

Clinical Trials (229)

Showing 20 of 229 trialsScroll for more
NCT07645469Phase 1

FH-WT1-E50 TCR T Cells With Azacitidine for the Treatment of Minimal Residual Disease Positive Acute Myeloid Leukemia

Recruiting
NCT06317649Phase 2

Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

Recruiting
NCT03660826Phase 2

Testing the Combination of Olaparib and Durvalumab, Cediranib and Durvalumab, Olaparib and Capivasertib, and Cediranib Alone in Recurrent or Refractory Endometrial Cancer Following the Earlier Phase of the Study That Tested Olaparib and Cediranib in Comparison to Cediranib Alone, and Olaparib Alone

Active Not Recruiting
NCT07758673Phase 1

Genetically Engineered Cells (BAFFR-CAR T Cells) for the Treatment of Relapsed or Refractory B-cell Acute Lymphoblastic Leukemia and B-cell Lymphoblastic Lymphoma

Not Yet Recruiting
NCT06661915Phase 2

A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)

Recruiting
NCT05907746Phase 2

Allogeneic Hematopoietic Stem Cell Transplantation With Briquilimab-Based Conditioning in Participants With GATA2 Deficiency

Active Not Recruiting
NCT06672146Phase 2

Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial)

Recruiting
NCT07605416Phase 2

Testing an Experimental Approach to Treat Patients With Plasma Cell Leukemia, The QUANTUM Trial

Recruiting
NCT06940297Phase 2

Dasatinib and Quercetin With CAR-T Therapy for the Treatment of Patients With Relapsed or Refractory Multiple Myeloma

Recruiting
NCT06577441Phase 2

Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial)

Recruiting
NCT05564377Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Recruiting
NCT06172296Phase 3

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Recruiting
NCT06649812Phase 2

Testing the Effectiveness of a Combination Targeted Therapy (ViPOR) for Patients With Relapsed and/or Refractory Aggressive B-cell Lymphoma

Recruiting
NCT04269902Phase 3

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

Recruiting
NCT06311227Phase 2

Venetoclax for the Treatment of Patients With Relapsed Hairy Cell Leukemia

Recruiting
NCT04994808Phase 2

Treosulfan-Based Versus Clofarabine-Based Conditioning Before Donor Hematopoietic Stem Cell Transplant for the Treatment of Myelodysplastic Syndromes or Acute Myeloid Leukemia

Terminated
NCT07463807Phase 1

Testing the Investigational Medication Combination of Teclistamab and Pomalidomide Compared to the Usual Treatment (Carfilzomib, Pomalidomide, and Dexamethasone) for Patients With Multiple Myeloma Who Have Relapsed Shortly After Treatment

Recruiting
NCT06609928Phase 1

FH-FOLR1 Chimeric Antigen Receptor T Cell Therapy for Treating Pediatric Patients With Relapsed or Refractory Acute Myeloid Leukemia

Recruiting
NCT05976763Phase 3

Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphoma

Recruiting
NCT04539366Phase 1

Testing a New Immune Cell Therapy, GD2-Targeted Modified T-cells (GD2CART), in Children, Adolescents, and Young Adults With Relapsed/Refractory Osteosarcoma and Neuroblastoma, GD2-CAR PERSIST Trial

Suspended

Drug Details

Intervention Type
PROCEDURE
Total Trials
229