Success Metrics

Clinical Success Rate
68.4%

Based on 26 completed trials

Completion Rate
68%(26/38)
Active Trials
55(43%)
Results Posted
112%(29 trials)
Terminated
12(9%)

Phase Distribution

Ph not_applicable
9
7%
Ph phase_3
15
12%
Ph phase_1
32
25%
Ph early_phase_1
1
1%
Ph phase_2
64
50%
Ph phase_4
2
2%

Phase Distribution

33

Early Stage

64

Mid Stage

17

Late Stage

Phase Distribution123 total trials
Early Phase 1First-in-human
1(0.8%)
Phase 1Safety & dosage
32(26.0%)
Phase 2Efficacy & side effects
64(52.0%)
Phase 3Large-scale testing
15(12.2%)
Phase 4Post-market surveillance
2(1.6%)
N/ANon-phased studies
9(7.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

63.4%

26 of 41 finished

Non-Completion Rate

36.6%

15 ended early

Currently Active

55

trials recruiting

Total Trials

127

all time

Status Distribution
Active(77)
Completed(26)
Terminated(15)
Other(9)

Detailed Status

Recruiting37
Completed26
Not yet recruiting22
Active, not recruiting18
Terminated12
unknown9

Development Timeline

Analytics

Development Status

Total Trials
127
Active
55
Success Rate
68.4%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (0.8%)
Phase 132 (26.0%)
Phase 264 (52.0%)
Phase 315 (12.2%)
Phase 42 (1.6%)
N/A9 (7.3%)

Trials by Status

not_yet_recruiting2217%
unknown97%
withdrawn32%
terminated129%
recruiting3729%
completed2620%
active_not_recruiting1814%

Recent Activity

Clinical Trials (127)

Showing 20 of 127 trialsScroll for more
NCT03739814Phase 2

Inotuzumab Ozogamicin and Blinatumomab With or Without Ponatinib in Treating Patients With Newly Diagnosed, Recurrent, or Refractory CD22-Positive B-Lineage Acute Lymphoblastic Leukemia

Recruiting
NCT04872790Phase 1

Venetoclax, Dasatinib, Prednisone, Rituximab and Blinatumomab for the Treatment of Newly Diagnosed or Relapsed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia or Mixed Phenotype Acute Leukemia

Active Not Recruiting
NCT07570173Phase 2

A Clinical Trial of MK-1045 in People With B-cell Acute Lymphoblastic Leukemia (MK-1045-005)

Not Yet Recruiting
NCT06124157Phase 2

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

Recruiting
NCT06308588Phase 1

Phase I/II Study of the Combination of Blinatumomab and Asciminib in Patients With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Recruiting
NCT06317662Phase 2

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

Recruiting
NCT07283640Phase 1

A Phase IB Trial of Subcutaneous Blinatumomab in Combination With Revumenib for Patients With KMT2A-rearranged Acute Lymphoblastic Leukemia

Not Yet Recruiting
NCT07178912Phase 2

Phase II Study of the Combination of Subcutaneous Blinatumomab and Olverembatinib in Patients With Philadelphia Chromosome (ph)-Positive and/or BCR::ABL1 Positive Acute Lymphoblastic Leukemia (ALL)

Not Yet Recruiting
NCT04307576Phase 3

A Treatment Study Protocol for Participants 0-45 Years With Acute Lymphoblastic Leukaemia

Recruiting
NCT07192237Phase 2

Phase 2 Study to Assess the Safety and Efficacy of Subcutaneous Blinatumomab in Patients With Measurable Residual Disease Positive B-cell Acute Lymphoblastic Leukemia

Not Yet Recruiting
NCT07153796Phase 2

A Phase 2 Study to Assess the Safety and Efficacy of Subcutaneous Blinatumomab in Combination With Low Intensity Chemotherapy in Older Patients With Newly Diagnosed B-cell Acute Lymphoblastic Leukemia

Recruiting
NCT03959085Phase 3

Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

Recruiting
NCT03914625Phase 3

A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia

Active Not Recruiting
NCT02101853Phase 3

Blinatumomab in Treating Younger Patients With Relapsed B-cell Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT07564453Phase 2

Full-course Immunotherapy Combined With Chemotherapy in Newly Diagnosed B-cell Acute Lymphoblastic Leukemia

Recruiting
NCT02003222Phase 3

Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT06533748Phase 2

Therapy for Newly Diagnosed Patients With B-Cell Precursor Acute Lymphoblastic Leukemia and Lymphoma

Recruiting
NCT04521231Phase 1

A Study of Subcutaneous Blinatumomab Administration in Participants With R/R and MRD+ B-ALL

Recruiting
NCT02879695Phase 1

Blinatumomab and Nivolumab With or Without Ipilimumab in Treating Patients With Poor-Risk Relapsed or Refractory CD19+ Precursor B-Lymphoblastic Leukemia

Active Not Recruiting
NCT04994717Phase 3

Study Comparing Blinatumomab Alternating With Low-intensity Chemotherapy Versus Standard of Care Chemotherapy for Older Adults With Newly Diagnosed Philadelphia-negative B-cell Precursor Acute Lymphoblastic Leukemia

Recruiting

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
127