Success Metrics

Clinical Success Rate
69.2%

Based on 9 completed trials

Completion Rate
69%(9/13)
Active Trials
1(6%)
Results Posted
33%(3 trials)
Terminated
4(22%)

Phase Distribution

Ph phase_2
9
50%
Ph phase_1
9
50%

Phase Distribution

9

Early Stage

9

Mid Stage

0

Late Stage

Phase Distribution18 total trials
Phase 1Safety & dosage
9(50.0%)
Phase 2Efficacy & side effects
9(50.0%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

64.3%

9 of 14 finished

Non-Completion Rate

35.7%

5 ended early

Currently Active

1

trials recruiting

Total Trials

18

all time

Status Distribution
Active(1)
Completed(9)
Terminated(5)
Other(3)

Detailed Status

Completed9
Terminated4
unknown3
Withdrawn1
Active, not recruiting1

Development Timeline

Analytics

Development Status

Total Trials
18
Active
1
Success Rate
69.2%
Most Advanced
Phase 2

Trials by Phase

Phase 19 (50.0%)
Phase 29 (50.0%)

Trials by Status

completed950%
unknown317%
withdrawn16%
terminated422%
active_not_recruiting16%

Recent Activity

Clinical Trials (18)

Showing 18 of 18 trials
NCT01597388Phase 1

AZD2014 and Fulvestrant in Patients With ER+ Advanced Metastatic Breast Cancer

Completed
NCT02299999Phase 2

SAFIR02_Breast - Efficacy of Genome Analysis as a Therapeutic Decision Tool for Patients With Metastatic Breast Cancer

Active Not Recruiting
NCT02398747Phase 1

Japanese Phase I Study of AZD2014 in Advanced Solid Malignancies

Completed
NCT02216786Phase 2

A Randomized Study of AZD2014 in Combination With Fulvestrant in Metastatic or Advanced Breast Cancer

Completed
NCT02599714Phase 1

Study of AZD2014 and Palbociclib in Patients With Estrogen Receptor Positive (ER+) Metastatic Breast Cancer

Completed
NCT02730923Phase 1

Hormone Receptor Positive endometrIal Carcinoma Treated by Dual mTORC1/mTORC2 Inhibitor and Anastrozole (VICTORIA)

Unknown
NCT02117167Phase 2

SAFIR02_Lung - Efficacy of Targeted Drugs Guided by Genomic Profiles in Metastatic NSCLC Patients

Completed
NCT02619864Phase 1

mTORC1/mTORC2 Kinase Inhibitor AZD2014 in Previously Treated Glioblastoma Multiforme

Completed
NCT03071874Phase 2

Vistusertib (AZD2014) For Recurrent Grade II-III Meningiomas

Unknown
NCT02831257Phase 2

AZD2014 In NF2 Patients With Progressive or Symptomatic Meningiomas

Completed
NCT02583542Phase 1

A Study of AZD2014 in Combination With Selumetinib in Patients With Advanced Cancers

Unknown
NCT02064608Phase 1

Investigating the Effects of AZD2014 Therapy Given Prior to Radical Prostatectomy in Men With High Risk Prostate Cancer

Completed
NCT03061708Phase 2

Trial of Single Agent AZD2014 in RICTOR Amplified GC Patients as Second-line Therapy

Terminated
NCT02449655Phase 2

Trial of AZD5363 Plus Paclitaxel /AZD2014 Plus Paclitaxel in Biomarker Negative (PIK3CA/MEK/RAS/TP53/MET) Gastric Adenocarcinoma Patients as Second-line Chemotherapy

Terminated
NCT03082833Phase 2

Phase II Trial of AZD2014 in TSC1/2 Mutated or TSC1/2 Null GC Patients as Second-line Chemotherapy

Terminated
NCT02780830Phase 1

AZD2014 Plus Novel Anti-Cancer Agents in Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Withdrawn
NCT01026402Phase 1

Study to Assess the Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Efficacy of AZD2014

Completed
NCT01793636Phase 2

A Study Comparing AZD2014 vs Everolimus in Patients With Metastatic Renal Cancer

Terminated

All 18 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
18