Success Metrics

Clinical Success Rate
33.3%

Based on 3 completed trials

Completion Rate
33%(3/9)
Active Trials
9(43%)
Results Posted
367%(11 trials)
Terminated
6(29%)

Phase Distribution

Ph phase_3
1
5%
Ph phase_4
1
5%
Ph phase_1
7
33%
Ph phase_2
11
52%

Phase Distribution

7

Early Stage

11

Mid Stage

2

Late Stage

Phase Distribution20 total trials
Phase 1Safety & dosage
7(35.0%)
Phase 2Efficacy & side effects
11(55.0%)
Phase 3Large-scale testing
1(5.0%)
Phase 4Post-market surveillance
1(5.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

33.3%

3 of 9 finished

Non-Completion Rate

66.7%

6 ended early

Currently Active

9

trials recruiting

Total Trials

21

all time

Status Distribution
Active(9)
Completed(3)
Terminated(6)
Other(3)

Detailed Status

Terminated6
Active, not recruiting6
unknown3
Recruiting3
Completed3

Development Timeline

Analytics

Development Status

Total Trials
21
Active
9
Success Rate
33.3%
Most Advanced
Phase 4

Trials by Phase

Phase 17 (35.0%)
Phase 211 (55.0%)
Phase 31 (5.0%)
Phase 41 (5.0%)

Trials by Status

unknown314%
recruiting314%
terminated629%
completed314%
active_not_recruiting629%

Recent Activity

Clinical Trials (21)

Showing 20 of 21 trialsScroll for more
NCT07257419Phase 1

CD45RA-depleted CD19-CAR T Cell Consolidation After TCRαβ+/CD19 B Cell-depleted Haploidentical Hematopoietic Cell Transplantation for Relapsed/Refractory CD19+ ALL and Lymphoma

Recruiting
NCT04224558Phase 1

Stem Cell Transplantation in Crohn's Disease

Recruiting
NCT04395222Phase 2

Tocilizumab for the Prevention of Graft Failure and GVHD in Haplo-Cord Transplantation

Active Not Recruiting
NCT01810588Phase 2

Targeting the IPA and Matching for the Non-Inherited Maternal Antigen for Haplo-Cord Transplantation

Active Not Recruiting
NCT03531736Phase 1

T Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation Conditioned With a Reduced Intensity Regimen in Patients With Hematologic Malignancies and Aplastic Anemia

Active Not Recruiting
NCT02790515Phase 2

Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior Transplantation

Active Not Recruiting
NCT04558736Phase 2

Haploidentical HCT for Severe Aplastic Anemia

Recruiting
NCT03597594Phase 1

Haplocompatible Transplant Using TCRα/β Depletion Followed by CD45RA-Depleted Donor Lymphocyte Infusions for Severe Combined Immunodeficiency (SCID)

Active Not Recruiting
NCT04202835Phase 2

ATG Plus PTCy vs ATG for CGVHD Prophylaxis

Active Not Recruiting
NCT04066114Phase 1

Treg Modulation With CD28 and IL-6 Receptor Antagonists

Completed
NCT06039436

Conditioning Regimen Containing Low Dose ATG for The Treatment of Acquired SAA Receiving sUCBT

Unknown
NCT03600909Phase 2

A Study of the Effect of Blood Stem Cell Transplant After Chemotherapy Alone in Patients With Fanconi Anemia

Terminated
NCT01790594Phase 2

Optimization of NULOJIX® Usage Towards Minimizing CNI Exposure in Simultaneous Pancreas and Kidney Transplantation

Terminated
NCT01856257Phase 2

Open-Label Phase 2 Trial of a Steroid-Free, CNI-Free, Belatacept-Based Immunosuppressive Regimen

Terminated
NCT02188719Phase 1

Donor-Alloantigen-Reactive Regulatory T Cell (darTregs) in Liver Transplantation

Terminated
NCT00566696Phase 2

Mismatched Family Member Donor Transplantation for Children and Young Adults With High Risk Hematological Malignancies

Completed
NCT01050764Phase 1

Haploidentical Allogeneic Transplant With Post-transplant Infusion of Regulatory T-cells

Terminated
NCT00260689Phase 2

Three Immunosuppressive Treatment Regimens for Severe Aplastic Anemia

Completed
NCT01621477Phase 2

T-Cell Replete Haploidentical Donor Hematopoietic Stem Cell Plus Natural Killer (NK) Cell Transplantation in Patients With Hematologic Malignancies Relapsed or Refractory Despite Previous Allogeneic Transplant

Terminated
NCT01217723Phase 3

Thymoglobulin in Unrelated Hematopoietic Progenitor Cell Transplantation

Unknown

Drug Details

Intervention Type
DRUG
Total Trials
21