Success Metrics

Clinical Success Rate
77.9%

Based on 102 completed trials

Completion Rate
78%(102/131)
Active Trials
39(19%)
Results Posted
92%(94 trials)
Terminated
29(14%)

Phase Distribution

Ph not_applicable
19
9%
Ph phase_2
110
53%
Ph phase_1
55
27%
Ph phase_3
11
5%
Ph early_phase_1
4
2%

Phase Distribution

59

Early Stage

110

Mid Stage

11

Late Stage

Phase Distribution199 total trials
Early Phase 1First-in-human
4(2.0%)
Phase 1Safety & dosage
55(27.6%)
Phase 2Efficacy & side effects
110(55.3%)
Phase 3Large-scale testing
11(5.5%)
N/ANon-phased studies
19(9.5%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

71.8%

102 of 142 finished

Non-Completion Rate

28.2%

40 ended early

Currently Active

39

trials recruiting

Total Trials

206

all time

Status Distribution
Active(43)
Completed(102)
Terminated(40)
Other(21)

Detailed Status

Completed102
Terminated29
Active, not recruiting20
Recruiting19
unknown18
Withdrawn11

Development Timeline

Analytics

Development Status

Total Trials
206
Active
39
Success Rate
77.9%
Most Advanced
Phase 3

Trials by Phase

Early Phase 14 (2.0%)
Phase 155 (27.6%)
Phase 2110 (55.3%)
Phase 311 (5.5%)
N/A19 (9.5%)

Trials by Status

recruiting199%
unknown189%
withdrawn115%
completed10250%
not_yet_recruiting42%
suspended31%
terminated2914%
active_not_recruiting2010%

Recent Activity

Clinical Trials (206)

Showing 20 of 206 trialsScroll for more
NCT05564390Phase 2

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Recruiting
NCT04293562Phase 3

A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

Recruiting
NCT07564453Phase 2

Full-course Immunotherapy Combined With Chemotherapy in Newly Diagnosed B-cell Acute Lymphoblastic Leukemia

Recruiting
NCT03007147Phase 3

Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT02101853Phase 3

Blinatumomab in Treating Younger Patients With Relapsed B-cell Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT02003222Phase 3

Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT01231412Phase 3

Graft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated Donor Peripheral Blood Stem Cell Transplant

Completed
NCT06735690Early Phase 1

Allogeneic CMV-Specific CD19-CAR T Cells Plus CMV-MVA Triplex Vaccine After Matched Related Donor Hematopoietic Cell Transplant for the Treatment of Patients With High-Risk Acute Lymphoblastic Leukemia

Recruiting
NCT03878199Phase 1

Testing the Effect of Taking Ruxolitinib and CPX-351 in Combination for the Treatment of Advanced Phase Myeloproliferative Neoplasms

Terminated
NCT07548983Phase 1

Ruxolitinib With Azacitidine Maintenance for the Treatment of Patients With Acute Myeloid Leukemia Undergoing Reduced Intensity Allogeneic Stem Cell Transplantation

Not Yet Recruiting
NCT06458244

The Efficacy of Allo-HSCT in ND HR-CBF-AML

Recruiting
NCT07349771Phase 2

Axatilimab Plus Standard of Care Therapy for the Prevention of Graft Versus Host Disease Following Allogeneic Hematopoietic Stem Cell Transplantation in Patients With Hematologic Cancer, ABRAXAS Trial

Not Yet Recruiting
NCT04859946Phase 2

Itacitinib for the Prevention of Graft Versus Host Disease

Active Not Recruiting
NCT04177004Phase 1

Human Lysozyme Goat Milk for the Prevention of Graft Versus Host Disease in Patients With Blood Cancer Undergoing a Donor Stem Cell Transplant

Suspended
NCT07500753Not Applicable

A Single-arm, Prospective Study of a Clad-LABU Conditioning Regimen in HSCT for R/R MDS/AML in Elderly Patients

Recruiting
NCT02250937Phase 2

Venetoclax and Sequential Busulfan, Cladribine, and Fludarabine Phosphate Before Donor Stem Cell Transplant in Treating Patients With Acute Myelogenous Leukemia or Myelodysplastic Syndrome

Active Not Recruiting
NCT01384513Phase 2

A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies

Completed
NCT03192397Phase 1

Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant

Active Not Recruiting
NCT04384692Phase 2

Peritransplant Ruxolitinib for Patients With Primary and Secondary Myelofibrosis

Active Not Recruiting
NCT06954987Phase 2

Venetoclax or Placebo in Combination With Reduced-Intensity Conditioning Hematopoietic Cell (Bone Marrow/Blood Stem Cell) Transplant and as Maintenance Therapy After Transplant in Patients With Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

Not Yet Recruiting

Drug Details

Intervention Type
PROCEDURE
Total Trials
206