Success Metrics

Clinical Success Rate
78.0%

Based on 103 completed trials

Completion Rate
78%(103/132)
Active Trials
38(18%)
Results Posted
94%(97 trials)
Terminated
29(14%)

Phase Distribution

Ph phase_2
110
53%
Ph phase_1
56
27%
Ph early_phase_1
4
2%
Ph not_applicable
19
9%
Ph phase_3
11
5%

Phase Distribution

60

Early Stage

110

Mid Stage

11

Late Stage

Phase Distribution200 total trials
Early Phase 1First-in-human
4(2.0%)
Phase 1Safety & dosage
56(28.0%)
Phase 2Efficacy & side effects
110(55.0%)
Phase 3Large-scale testing
11(5.5%)
N/ANon-phased studies
19(9.5%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

72.0%

103 of 143 finished

Non-Completion Rate

28.0%

40 ended early

Currently Active

38

trials recruiting

Total Trials

207

all time

Status Distribution
Active(43)
Completed(103)
Terminated(40)
Other(21)

Detailed Status

Completed103
Terminated29
Active, not recruiting20
Recruiting18
unknown18
Withdrawn11

Development Timeline

Analytics

Development Status

Total Trials
207
Active
38
Success Rate
78.0%
Most Advanced
Phase 3

Trials by Phase

Early Phase 14 (2.0%)
Phase 156 (28.0%)
Phase 2110 (55.0%)
Phase 311 (5.5%)
N/A19 (9.5%)

Trials by Status

completed10350%
suspended31%
terminated2914%
active_not_recruiting2010%
not_yet_recruiting52%
recruiting189%
withdrawn115%
unknown189%

Recent Activity

Clinical Trials (207)

Showing 20 of 207 trialsScroll for more
NCT05564390Phase 2

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Recruiting
NCT02003222Phase 3

Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT07737769Phase 1

Arsenic Trioxide to Prevent Relapse in Patients Undergoing Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia or Myelodysplastic Syndrome

Not Yet Recruiting
NCT02101853Phase 3

Blinatumomab in Treating Younger Patients With Relapsed B-cell Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT00792948Phase 2

Combination Chemotherapy With or Without Donor Stem Cell Transplant in Treating Patients With Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT04293562Phase 3

A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

Recruiting
NCT03531736Phase 1

T Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation Conditioned With a Reduced Intensity Regimen in Patients With Hematologic Malignancies and Aplastic Anemia

Active Not Recruiting
NCT03712878Phase 2

2-Step Approach to Stem Cell Transplant in Treating Participants With Hematological Malignancies

Completed
NCT07046078Phase 2

Combination Chemotherapy (FLAG-Ida) Followed Immediately by Reduced-Intensity Total Body Radiation Therapy and Donor Hematopoietic Cell Transplant for the Treatment of Adults Age 60 and Older With Newly Diagnosed Adverse-Risk Acute Myeloid Leukemia or Other High-Grade Myeloid Cancer

Recruiting
NCT04022239Phase 1

Bendamustine With or Without Cyclophosphamide in Preventing GVHD in Patients Undergoing Stem Cell Transplant

Recruiting
NCT04177004Phase 1

Human Lysozyme Goat Milk for the Prevention of Graft Versus Host Disease in Patients With Blood Cancer Undergoing a Donor Stem Cell Transplant

Active Not Recruiting
NCT06903702Phase 2

A Study of Azacitidine and Venetoclax Versus a Stem Cell Transplant in People 65 Years and Older With Acute Myeloid Leukemia

Not Yet Recruiting
NCT05139004Phase 1

90Y-DOTA-anti-CD25 Basiliximab, Fludarabine, Melphalan, and Total Marrow and Lymphoid Irradiation for the Treatment of High-Risk Acute Leukemia or Myelodysplastic Syndrome

Active Not Recruiting
NCT07548983Phase 1

Ruxolitinib With Azacitidine Maintenance for the Treatment of Patients With Acute Myeloid Leukemia Undergoing Reduced Intensity Allogeneic Stem Cell Transplantation

Recruiting
NCT02094794Phase 2

Total Marrow and Lymphoid Irradiation and Chemotherapy Before DSCT in Treating Patients With High-Risk ALL or AML

Active Not Recruiting
NCT06815003Phase 2

Vedolizumab Plus Post-transplant Cyclophosphamide and Short Course Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation After Reduced Intensity Conditioning

Recruiting
NCT05656248Phase 2

Study of CPX-351 (VYXEOS) in Individuals < 22 Years With Secondary Myeloid Neoplasms

Active Not Recruiting
NCT03118492Phase 1

Combination Chemotherapy, Total Body Irradiation, and Donor Blood Stem Cell Transplant in Treating Patients With Secondary Myelofibrosis

Active Not Recruiting
NCT03247088Phase 1

Sorafenib, Busulfan and Fludarabine in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia Undergoing Donor Stem Cell Transplant

Active Not Recruiting
NCT06447987Phase 1

Humanized CD19-Specific CAR T Cells for the Treatment of Patients With Positive Relapsed or Refractory CD19 Positive B-Cell Acute Lymphoblastic Leukemia

Suspended

Drug Details

Intervention Type
PROCEDURE
Total Trials
207