Success Metrics

Clinical Success Rate
82.1%

Based on 23 completed trials

Completion Rate
82%(23/28)
Active Trials
27(44%)
Results Posted
87%(20 trials)
Terminated
5(8%)

Phase Distribution

Ph phase_1
15
24%
Ph phase_4
1
2%
Ph phase_2
25
40%
Ph phase_3
8
13%
Ph early_phase_1
1
2%
Ph not_applicable
1
2%

Phase Distribution

16

Early Stage

25

Mid Stage

9

Late Stage

Phase Distribution51 total trials
Early Phase 1First-in-human
1(2.0%)
Phase 1Safety & dosage
15(29.4%)
Phase 2Efficacy & side effects
25(49.0%)
Phase 3Large-scale testing
8(15.7%)
Phase 4Post-market surveillance
1(2.0%)
N/ANon-phased studies
1(2.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

79.3%

23 of 29 finished

Non-Completion Rate

20.7%

6 ended early

Currently Active

27

trials recruiting

Total Trials

62

all time

Status Distribution
Active(30)
Completed(23)
Terminated(6)
Other(3)

Detailed Status

Completed23
Recruiting16
Active, not recruiting11
Terminated5
Not yet recruiting3
unknown3

Development Timeline

Analytics

Development Status

Total Trials
62
Active
27
Success Rate
82.1%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (2.0%)
Phase 115 (29.4%)
Phase 225 (49.0%)
Phase 38 (15.7%)
Phase 41 (2.0%)
N/A1 (2.0%)

Trials by Status

withdrawn12%
active_not_recruiting1118%
not_yet_recruiting35%
unknown35%
completed2337%
recruiting1626%
terminated58%

Recent Activity

Clinical Trials (62)

Showing 20 of 62 trialsScroll for more
NCT05170204Phase 3

A Study Evaluating the Efficacy and Safety of Multiple Therapies in Cohorts of Participants With Locally Advanced, Unresectable, Stage III Non-Small Cell Lung Cancer (NSCLC)

Active Not Recruiting
NCT06862869

Real World Clinical Outcomes of Resected ALK-Positive Early Stage NSCLC Patients Treated With Alectinib as Adjuvant Therapy

Recruiting
NCT04774718Phase 1

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Alectinib in Pediatric Participants With ALK Fusion-Positive Solid or CNS Tumors

Recruiting
NCT06765109Phase 3

Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC

Recruiting
NCT02314481Phase 2

Deciphering Antitumour Response and Resistance With INtratumour Heterogeneity

Completed
NCT07560410Phase 1

Treatment of Truncated ALK-positive Bone Cancer Using Crizotinib (Xalkori) or Alectinib (Alecensa)

Not Yet Recruiting
NCT03768063Phase 3

A Study in Patients Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study

Active Not Recruiting
NCT04116541Phase 2

A Study Evaluating the Activity of Anti-cancer Treatments Targeting Tumor Molecular Alterations/Characteristics in Advanced / Metastatic Tumors.

Recruiting
NCT03737994Phase 2

Targeted Treatment for ALK Positive Patients Who Have Previously Been Treated for Non-squamous Non-small Cell Lung Cancer

Terminated
NCT04764188

An Observational Study to Evaluate the Real-World Clinical Management and Outcomes of ALK-Positive Advanced NSCLC Participants Treated With Alectinib

Active Not Recruiting
NCT05987644Phase 1

Delayed or Upfront Brain RAdiotherapy in Treatment naïve Lung Cancer Patients With Asymptomatic or Minimally Symptomatic Brain Metastases and ALK rEarrangements

Recruiting
NCT06624059Phase 1

A Study to See How Well and How Safely Different Treatments Work in a Group of Participants With Non-Small Cell Lung Cancer (NSCLC)

Active Not Recruiting
NCT07001384Phase 1

A Study of Alectinib and Duvelisib in People With Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma (ALK+ALCL)

Recruiting
NCT04589845Phase 2

Tumor-agnostic Precision Immuno-oncology and Somatic Targeting Rational for You (TAPISTRY) Platform Study

Active Not Recruiting
NCT02838420Phase 3

A Study to Evaluate and Compare the Efficacy and Safety of Alectinib Versus Crizotinib and to Evaluate the Pharmacokinetics of Alectinib in Asian Participants With Treatment-Naive Anaplastic Lymphoma Kinase (ALK)-Positive Advanced Non-Small Cell Lung Cancer (NSCLC)

Active Not Recruiting
NCT03178552Phase 2

A Study to Evaluate the Efficacy and Safety of Multiple Targeted Therapies as Treatments for Participants With Non-Small Cell Lung Cancer (NSCLC)

Active Not Recruiting
NCT04302025Phase 2

A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC)

Recruiting
NCT03194893Phase 3

A Rollover Study of Alectinib in Patients With Anaplastic Lymphoma Kinase (ALK)-Positive or Rearranged During Transfection (RET)-Positive Cancer

Active Not Recruiting
NCT05722886Phase 2

DETERMINE (Determining Extended Therapeutic Indications for Existing Drugs in Rare Molecularly Defined Indications Using a National Evaluation Platform Trial) - Master Screening Protocol

Recruiting
NCT05770037Phase 2

DETERMINE Trial Treatment Arm 01: Alectinib in Adult, Paediatric and Teenage/Young Adult Patients With ALK Positive Cancers

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
62