Success Metrics

Clinical Success Rate
83.3%

Based on 25 completed trials

Completion Rate
83%(25/30)
Active Trials
25(40%)
Results Posted
80%(20 trials)
Terminated
5(8%)

Phase Distribution

Ph not_applicable
1
2%
Ph early_phase_1
1
2%
Ph phase_1
15
24%
Ph phase_3
8
13%
Ph phase_4
1
2%
Ph phase_2
25
40%

Phase Distribution

16

Early Stage

25

Mid Stage

9

Late Stage

Phase Distribution51 total trials
Early Phase 1First-in-human
1(2.0%)
Phase 1Safety & dosage
15(29.4%)
Phase 2Efficacy & side effects
25(49.0%)
Phase 3Large-scale testing
8(15.7%)
Phase 4Post-market surveillance
1(2.0%)
N/ANon-phased studies
1(2.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

80.6%

25 of 31 finished

Non-Completion Rate

19.4%

6 ended early

Currently Active

25

trials recruiting

Total Trials

62

all time

Status Distribution
Active(28)
Completed(25)
Terminated(6)
Other(3)

Detailed Status

Completed25
Recruiting16
Active, not recruiting9
Terminated5
unknown3
Not yet recruiting3

Development Timeline

Analytics

Development Status

Total Trials
62
Active
25
Success Rate
83.3%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (2.0%)
Phase 115 (29.4%)
Phase 225 (49.0%)
Phase 38 (15.7%)
Phase 41 (2.0%)
N/A1 (2.0%)

Trials by Status

unknown35%
withdrawn12%
active_not_recruiting915%
completed2540%
not_yet_recruiting35%
recruiting1626%
terminated58%

Recent Activity

Clinical Trials (62)

Showing 20 of 62 trialsScroll for more
NCT03768063Phase 3

A Study in Patients Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study

Active Not Recruiting
NCT03445000Phase 2

ALEctinib for the Treatment of Pretreated RET-rearranged Advanced Non-small Cell Lung Cancer

Terminated
NCT06765109Phase 3

Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC

Recruiting
NCT04764188

An Observational Study to Evaluate the Real-World Clinical Management and Outcomes of ALK-Positive Advanced NSCLC Participants Treated With Alectinib

Active Not Recruiting
NCT04302025Phase 2

A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC)

Recruiting
NCT04116541Phase 2

A Study Evaluating the Activity of Anti-cancer Treatments Targeting Tumor Molecular Alterations/Characteristics in Advanced / Metastatic Tumors.

Recruiting
NCT06862869

Real World Clinical Outcomes of Resected ALK-Positive Early Stage NSCLC Patients Treated With Alectinib as Adjuvant Therapy

Recruiting
NCT04774718Phase 1

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Alectinib in Pediatric Participants With ALK Fusion-Positive Solid or CNS Tumors

Recruiting
NCT06624059Phase 1

A Study to See How Well and How Safely Different Treatments Work in a Group of Participants With Non-Small Cell Lung Cancer (NSCLC)

Active Not Recruiting
NCT05722886Phase 2

DETERMINE (Determining Extended Therapeutic Indications for Existing Drugs in Rare Molecularly Defined Indications Using a National Evaluation Platform Trial) - Master Screening Protocol

Recruiting
NCT02838420Phase 3

A Study to Evaluate and Compare the Efficacy and Safety of Alectinib Versus Crizotinib and to Evaluate the Pharmacokinetics of Alectinib in Asian Participants With Treatment-Naive Anaplastic Lymphoma Kinase (ALK)-Positive Advanced Non-Small Cell Lung Cancer (NSCLC)

Completed
NCT05525858

KPMNG Study of MOlecular Profiling Guided Therapy Based on Genomic Alterations in Advanced Solid Tumors II

Recruiting
NCT03194893Phase 3

A Rollover Study of Alectinib in Patients With Anaplastic Lymphoma Kinase (ALK)-Positive or Rearranged During Transfection (RET)-Positive Cancer

Completed
NCT03178552Phase 2

A Study to Evaluate the Efficacy and Safety of Multiple Targeted Therapies as Treatments for Participants With Non-Small Cell Lung Cancer (NSCLC)

Active Not Recruiting
NCT02075840Phase 3

A Study Comparing Alectinib With Crizotinib in Treatment-Naive Anaplastic Lymphoma Kinase-Positive Advanced Non-Small Cell Lung Cancer Participants

Completed
NCT07001384Phase 1

A Study of Alectinib and Duvelisib in People With Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma (ALK+ALCL)

Recruiting
NCT07560410Phase 1

Treatment of Truncated ALK-positive Bone Cancer Using Crizotinib (Xalkori) or Alectinib (Alecensa)

Not Yet Recruiting
NCT03202940Phase 1

A Phase IB/II Study of Alectinib Combined With Cobimetinib in Advanced ALK-Rearranged (ALK+) NSCLC

Active Not Recruiting
NCT04589845Phase 2

Tumor-agnostic Precision Immuno-oncology and Somatic Targeting Rational for You (TAPISTRY) Platform Study

Active Not Recruiting
NCT05170204Phase 3

A Study Evaluating the Efficacy and Safety of Multiple Therapies in Cohorts of Participants With Locally Advanced, Unresectable, Stage III Non-Small Cell Lung Cancer (NSCLC)

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
62