Success Metrics

Clinical Success Rate
78.9%

Based on 15 completed trials

Completion Rate
79%(15/19)
Active Trials
0(0%)
Results Posted
40%(6 trials)
Terminated
4(20%)

Phase Distribution

Ph phase_1
5
25%
Ph phase_2
15
75%

Phase Distribution

5

Early Stage

15

Mid Stage

0

Late Stage

Phase Distribution20 total trials
Phase 1Safety & dosage
5(25.0%)
Phase 2Efficacy & side effects
15(75.0%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

75.0%

15 of 20 finished

Non-Completion Rate

25.0%

5 ended early

Currently Active

0

trials recruiting

Total Trials

20

all time

Status Distribution
Completed(15)
Terminated(5)

Detailed Status

Completed15
Terminated4
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
20
Active
0
Success Rate
78.9%
Most Advanced
Phase 2

Trials by Phase

Phase 15 (25.0%)
Phase 215 (75.0%)

Trials by Status

completed1575%
terminated420%
withdrawn15%

Recent Activity

Clinical Trials (20)

Showing 20 of 20 trials
NCT02920892Phase 2

AFQ056 for Language Learning in Children With FXS

Completed
NCT03242928Phase 2

Study to Investigate Whether AFQ056 Reduces Cocaine Use in Patients Diagnosed With Cocaine Use Disorder (CUD)

Completed
NCT04771143Phase 1

Study to Assess Safety, Tolerability, and Interactions of Cocaine and Oral AFQ056

Withdrawn
NCT01173731Phase 2

Open Label, Safety, Tolerability and Efficacy of AFQ056 in Parkinson's Patients With L-dopa Induced Dyskinesias

Completed
NCT01491932Phase 2

Open-label, Long-term Safety Extension Study of AFQ056 in Parkinson's Patients With L-dopa Induced Dyskinesias

Completed
NCT01385592Phase 2

Evaluation of the Efficacy and Safety of AFQ056 in Parkinson's Patients With L-dopa Induced Dyskinesias

Completed
NCT01253629Phase 2

Safety and Efficacy of AFQ056 in Adult Patients With Fragile X Syndrome

Completed
NCT01491529Phase 2

Evaluation of the Efficacy and Safety of Modified Release AFQ056 in Parkinson's Patients With L-dopa Induced Dyskinesias

Completed
NCT01456663Phase 1

A Study to Evaluate the Pharmacokinetics of AFQ056 in Subjects With Hepatic Impairment Compared to Healthy Subjects

Completed
NCT01482143Phase 1

Clinical Study to Assess the Pharmacokinetics, Safety and Tolerability of Single and Multiple Oral Doses of AFQ056 in Children With Fragile X Syndrome (FXS)

Completed
NCT01442259Phase 1

An Open-label, Parallel-group Study to Determine the Pharmacokinetics of a Single Dose of AFQ056 in Subjects With Renal Impairment Compared to Healthy Subjects

Completed
NCT00986414Phase 2

Evaluation of the Efficacy and Safety of AFQ056 in Reducing Moderate to Severe L-dopa Induced Dyskinesias in Patients With Parkinson's Disease

Completed
NCT01813019Phase 2

Study to Evaluate the Effect of AFQ056 in Obsessive Compulsive Disorder (OCD) Patients Resistant to Selective Serotonin Reuptake Inhibitor (SSRI) Therapy

Terminated
NCT01348087Phase 2

Long-term, Safety, Tolerability and Efficacy Study of AFQ056 in Adult Patients With Fragile X Syndrome

Terminated
NCT00888004Phase 2

Efficacy and Safety of AFQ056 in Reducing L-dopa Induced Dyskinesias in Parkinson's Disease Patients

Completed
NCT01433354Phase 2

Long-term, Safety and Tolerability Study of AFQ056 in Adolescent Patients With Fragile X Syndrome (Open-label)

Terminated
NCT01357239Phase 2

Safety and Efficacy of AFQ056 in Adolescent Patients With Fragile X Syndrome

Completed
NCT01019473Phase 2

Efficacy, Safety and Tolerability of AFQ056 in Patients With Huntington's Disease in Reducing Chorea

Terminated
NCT00582673Phase 2

Efficacy and Safety of AFQ056 in Reducing L-dopa Induced Dyskinesias in Parkinson's Disease Patients, and Safety in Combination With L-dopa

Completed
NCT00414856Phase 1

Effects of AFQ056 and Baclofen on Meal-Induced Gastroesophageal Reflux

Completed

All 20 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
20