Success Metrics

Clinical Success Rate
78.3%

Based on 18 completed trials

Completion Rate
78%(18/23)
Active Trials
14(28%)
Results Posted
72%(13 trials)
Terminated
5(10%)

Phase Distribution

Ph early_phase_1
1
2%
Ph phase_3
5
10%
Ph phase_1
25
50%
Ph phase_2
19
38%

Phase Distribution

26

Early Stage

19

Mid Stage

5

Late Stage

Phase Distribution50 total trials
Early Phase 1First-in-human
1(2.0%)
Phase 1Safety & dosage
25(50.0%)
Phase 2Efficacy & side effects
19(38.0%)
Phase 3Large-scale testing
5(10.0%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

62.1%

18 of 29 finished

Non-Completion Rate

37.9%

11 ended early

Currently Active

14

trials recruiting

Total Trials

50

all time

Status Distribution
Active(19)
Completed(18)
Terminated(11)
Other(2)

Detailed Status

Completed18
Recruiting10
Withdrawn6
Not yet recruiting5
Terminated5
Active, not recruiting4

Development Timeline

Analytics

Development Status

Total Trials
50
Active
14
Success Rate
78.3%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (2.0%)
Phase 125 (50.0%)
Phase 219 (38.0%)
Phase 35 (10.0%)

Trials by Status

active_not_recruiting48%
withdrawn612%
unknown24%
not_yet_recruiting510%
completed1836%
recruiting1020%
terminated510%

Recent Activity

Clinical Trials (50)

Showing 20 of 50 trialsScroll for more
NCT06469944Phase 1

Substudy 06C: A Study of Investigational Agents With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)

Recruiting
NCT07043400Phase 3

A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy in Patients With Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

Recruiting
NCT03281369Phase 1

A Study of Multiple Immunotherapy-Based Treatment Combinations in Patients With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Cancer (G/GEJ) or Esophageal Cancer (Morpheus-Gastric and Esophageal Cancer)

Terminated
NCT06901531Phase 3

A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

Recruiting
NCT05464030Phase 1

Anti-CEACAM5 ADC M9140 in Advanced Solid Tumors (PROCEADE-CRC-01)

Active Not Recruiting
NCT07733180Phase 2

A Study Investigating Alternate Schedules of Tislelizumab Plus Chemotherapy in Japanese Patients With First-line Advanced ESCC

Not Yet Recruiting
NCT07554521Phase 2

A Study to Evaluate Efficacy and Safety of Tislelizumab Plus Chemotherapy for Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Adenocarcinoma and Esophageal Squamous Cell Carcinoma in Racial and Ethnic Minority Patients in the United States

Recruiting
NCT06131840Phase 1

A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

Recruiting
NCT07069712Phase 2

A Study of Novel Agents or Combinations as Perioperative Treatment in Participants With Locally Advanced Resectable Gastroesophageal Adenocarcinoma

Recruiting
NCT06780111Phase 1

Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06)

Recruiting
NCT07662031Phase 2

Tovecimig Plus FOLFIRI in Second Line Metastatic Colorectal Cancer

Not Yet Recruiting
NCT05647122Phase 1

First in Human Study of AZD9592 in Solid Tumors

Active Not Recruiting
NCT06941857Phase 2

NC410 and FOLFIRINOX in Combination With Nivolumab With or Without Ipilimumab in Patients With Untreated Metastatic Pancreatic Cancer

Recruiting
NCT07256782Phase 1

A Study of QLC5508 Combinations in Patients With Advanced Solid Tumors

Recruiting
NCT05417386Phase 1

FOLFIRINOX + NIS793 in Pancreatic Cancer

Terminated
NCT03184870Phase 1

A Study of BMS-813160 in Combination With Chemotherapy or Nivolumab in Participants With Advanced Solid Tumors

Completed
NCT00082706Phase 2

Fluorouracil, Leucovorin, Gemcitabine, and Cisplatin in Treating Patients With Metastatic or Unresectable Adenocarcinoma of the Urothelium or Urachal Remnant

Active Not Recruiting
NCT02008656Phase 2

Trial Evaluating 3-year Disease Free Survival in Patients With Locally Advanced Rectal Cancer Treated With Chemoradiation Plus Induction or Consolidation Chemotherapy and Total Mesorectal Excision or Non-operative Management

Active Not Recruiting
NCT06856447Phase 1

The Role of Coenzyme Q10 in the Prophylaxis of Oxaliplatin Induced Peripheral Neuropathy in Patients With Colorectal Cancer

Recruiting
NCT03169790Phase 1

QUILT-3.052: NANT Non-Hodgkin Lymphoma (NHL) Vaccine: Combination Immunotherapy in Subjects With Relapsed CD20-positive NHL

Withdrawn

Drug Details

Intervention Type
DRUG
Total Trials
50