Key Insights

Highlights

Success Rate

78% trial completion

Published Results

17 trials with published results (16%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

10.6%

11 terminated out of 104 trials

Success Rate

78.4%

-8.1% vs benchmark

Late-Stage Pipeline

10%

10 trials in Phase 3/4

Results Transparency

43%

17 of 40 completed with results

Key Signals

17 with results78% success11 terminated

Data Visualizations

Phase Distribution

84Total
Not Applicable (11)
Early P 1 (1)
P 1 (36)
P 2 (26)
P 3 (8)
P 4 (2)

Trial Status

Completed40
Recruiting22
Active Not Recruiting13
Unknown11
Terminated11
Withdrawn3

Trial Success Rate

78.4%

Benchmark: 86.6%

Based on 40 completed trials

Clinical Trials (104)

Showing 20 of 20 trials
NCT07747935Phase 1Not Yet RecruitingPrimary

Study of Neoadjuvant RBP-01 In Patients With Primary Uveal Melanoma

NCT06007690Phase 3Active Not Recruiting

A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma

NCT03417739Phase 2TerminatedPrimary

A Phase II Study of BVD-523 in Metastatic Uveal Melanoma

NCT05607095Phase 1RecruitingPrimary

A Study of LN-144 or LN-145 in People With Advanced Uveal Melanoma, Undifferentiated Pleomorphic Sarcoma, Dedifferentiated Liposarcoma, or Angiosarcoma

NCT04328844Phase 1Active Not Recruiting

A Study to Assess a PI3Kδ Inhibitor (IOA-244) in Patients With Metastatic Cancers

NCT03635632Phase 1Active Not Recruiting

C7R-GD2.CART Cells for Patients With Relapsed or Refractory Neuroblastoma and Other GD2 Positive Cancers (GAIL-N)

NCT07501117Phase 1RecruitingPrimary

Neoadjuvant Immunotherapy for Patients With High-risk Eye Melanoma

NCT06246149Phase 3RecruitingPrimary

Adjuvant Tebentafusp in High Risk Ocular Melanoma

NCT05524935Phase 2Active Not RecruitingPrimary

Olaparib in Combination With Pembrolizumab for Advanced Uveal Melanoma

NCT06932757Phase 2RecruitingPrimary

Adjuvant Quisinostat in High-Risk Uveal Melanoma

NCT07015190Phase 3RecruitingPrimary

Neoadjuvant Darovasertib in Primary Uveal Melanoma

NCT05377957Active Not RecruitingPrimary

Prospective Registration Of Patient Data and Quality of Life in Eye Melanoma Patients

NCT05628883Phase 1Completed

Proof of Concept of TBio-4101, Lymphodepleting Chemo, IL-2 for Relapsed/Refractory Melanoma

NCT06075589Not ApplicableActive Not RecruitingPrimary

Psychoeducation for Uveal Melanoma

NCT06550674Not ApplicableRecruitingPrimary

Identification of New Candidate Genes for Hereditary Predisposition to Uveal Melanoma

NCT04119024Phase 1Recruiting

Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors

NCT03070392Phase 2CompletedPrimary

Safety and Efficacy of IMCgp100 Versus Investigator Choice in Advanced Uveal Melanoma

NCT05907954Phase 2Active Not RecruitingPrimary

(Neo)Adjuvant IDE196 (Darovasertib) in Patients With Localized Ocular Melanoma

NCT07364474Not ApplicableRecruitingPrimary

Immune Response to Percutaneous Hepatic Perfusion With Melphalan for Ocular Melanoma Metastatic to the Liver

NCT04792463RecruitingPrimary

Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition Syndrome

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