Key Insights

Highlights

Success Rate

69% trial completion

Published Results

56 trials with published results (16%)

Research Maturity

107 completed trials (31% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

14.0%

49 terminated out of 349 trials

Success Rate

68.6%

-17.9% vs benchmark

Late-Stage Pipeline

5%

18 trials in Phase 3/4

Results Transparency

52%

56 of 107 completed with results

Key Signals

56 with results69% success49 terminated

Data Visualizations

Phase Distribution

276Total
Not Applicable (27)
Early P 1 (4)
P 1 (121)
P 2 (106)
P 3 (16)
P 4 (2)

Trial Status

Completed107
Recruiting86
Terminated49
Unknown44
Active Not Recruiting41
Withdrawn13

Trial Success Rate

68.6%

Benchmark: 86.5%

Based on 107 completed trials

Clinical Trials (349)

Showing 20 of 20 trials
NCT07416123Phase 1Recruiting

A Study of GEN1106 in Participants With Solid Tumors

NCT05646485Not ApplicableRecruiting

Bladder Cancer Screening Trial

NCT07241793Phase 2RecruitingPrimary

Phase II Study of Trastuzumab Rezetecan or in Combination With Adebrelimab in HER2-Expressing Locally Advanced or Metastatic Urothelial Carcinoma (la/mUC)

NCT06682728Phase 2RecruitingPrimary

Adjuvant Sacituzumab Govitecan and Nivolumab in Muscle-Invasive Urothelial Carcinoma at High-Risk Recurrence

NCT06774131Phase 3Recruiting

A Phase 3 Single-arm Study of UGN-104 for the Treatment of Low-grade Upper Tract Urothelial Cancer

NCT05562830Phase 1RecruitingPrimary

A Substudy of Investigational Agents in Programmed Cell Death-1/Ligand 1 (PD-1/L1) Refractory Locally Advanced or Metastatic Urothelial Carcinoma (mUC) (MK-3475-04A)

NCT04943380Completed

Efficacy and Utility of Cxbladder Tests in Hematuria Patients

NCT05889195RecruitingPrimary

Detection and Risk Stratification in Veterans Presenting With Microscopic Hematuria

NCT03967977Phase 3Active Not RecruitingPrimary

Study of Tislelizumab in Combination With Chemotherapy Compared to Chemotherapy Alone for Participants With Urothelial Carcinoma

NCT04879329Phase 2RecruitingPrimary

A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2

NCT06966024Phase 1Recruiting

Study of DCC-2812 in Participants With Advanced Genitourinary Cancers

NCT05911295Phase 3Active Not RecruitingPrimary

Disitamab Vedotin With Pembrolizumab vs Chemotherapy in Previously Untreated Urothelial Cancer Expressing HER2

NCT06857175Phase 3RecruitingPrimary

A Study Comparing BL-B01D1 With Chemotherapy of Physician's Choice in Patients With Recurrent or Metastatic Urothelial Carcinoma(PANKU-Bladder01)

NCT07421700Phase 1Recruiting

Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer

NCT05861947Phase 1Terminated

A Phase 1 Clinical Trial of AUR106 in Patients With Relapsed Advanced Malignancies

NCT07322263Phase 2Recruiting

Intravesical GEM/DOCE for HR BCG-Unresponsive NMIBC

NCT07532902Phase 1Recruiting

A Study of BMS-986504 With Standard-of-Care Therapy for People With Solid Tumor Cancer

NCT03317158Phase 1RecruitingPrimary

Modern Immunotherapy in BCG-Unresponsive, BCG-Relapsing and High Risk BCG-Naive Non-Muscle Invasive Urothelial Carcinoma of the Bladder

NCT05581004Phase 1Recruiting

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of Enzelkitug as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors

NCT06443944Unknown

An Expanded Access Program of Cretostimogene Grenadenorepvec for Treatment of NMIBC for Patients Unresponsive to BCG

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