Key Insights

Highlights

Success Rate

92% trial completion (above average)

Published Results

13 trials with published results (37%)

Clinical Risk Assessment

Based on trial outcomes

Low Risk

Score: 17/100

Termination Rate

5.7%

2 terminated out of 35 trials

Success Rate

91.7%

+5.2% vs benchmark

Late-Stage Pipeline

43%

15 trials in Phase 3/4

Results Transparency

59%

13 of 22 completed with results

Key Signals

13 with results92% success

Data Visualizations

Phase Distribution

34Total
Not Applicable (4)
Early P 1 (1)
P 1 (5)
P 2 (9)
P 3 (9)
P 4 (6)

Trial Status

Completed22
Unknown9
Terminated2
Not Yet Recruiting1
Recruiting1

Trial Success Rate

91.7%

Benchmark: 86.5%

Based on 22 completed trials

Clinical Trials (35)

Showing 20 of 20 trials
NCT04393675Phase 1TerminatedPrimary

Study to Investigate the Safety of LT5001 Drug Product for Uremic Pruritus in Hemodialysis Patients

NCT03802617Phase 2CompletedPrimary

A Clinical Study of MR13A9 in Hemodialysis Patients With Pruritus.

NCT05885737Phase 3CompletedPrimary

Phase 3 Study of Difelikefalin in Haemodialysis Chinese Adult Subjects With Moderate-to-Severe Pruritus

NCT04711603Phase 3CompletedPrimary

A Phase III Clinical Study of MR13A9 in Hemodialysis Patients With Pruritus.

NCT02373215Phase 1CompletedPrimary

Phase 1 Study of Nalbuphine HCl ER Tablets in Hemodialysis Patients With Uremic Pruritus

NCT02143973Phase 2CompletedPrimary

Open Label Extension Study of Nalbuphine HCl ER in Hemodialysis Patients With Uremic Pruritus

NCT02143648Phase 2CompletedPrimary

Study of Nalbuphine HCl ER Tablets in Hemodialysis Patients With Uremic Pruritus

NCT06466421Phase 4CompletedPrimary

Fexofenadine Versus Gabapentin for Uremic Pruritus in Patients on Regular Hemodialysis

NCT06579066Phase 2Not Yet Recruiting

The Effect of Probiotics vs Activated Charcoal in the Management of CKD Patients Suffering From Uremic Pruritus.

NCT06446310Phase 3RecruitingPrimary

Phase 3 Study of QLG2198 in Haemodialysis Chinese Adult Subjects With Moderate-to-Severe Pruritus

NCT06159686Phase 1CompletedPrimary

The Efficacy of Hemp-containing Cream Versus Placebo in the Treatment of Uremic Pruritus

NCT04639674Phase 4CompletedPrimary

AST-120 in Hemodialysis Patients With Uremic Pruritus

NCT05575193Not ApplicableCompleted

Acupressure on Uremic Pruritus and Sleep Quality Among Patients Receiving Hemodialysis

NCT05525234Phase 4Unknown

A Study of Thalidomide in the Treatment of Refractory Uremic Pruritus

NCT04470154Phase 2CompletedPrimary

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of HSK21542 Injection in Subjects Undergoing Hemodialysis

NCT05466045Not ApplicableUnknownPrimary

Using of Extra Virgin Olive Oil in Hemodialysis Patients to Improve Pruritus and Sleep Disorders

NCT05031546UnknownPrimary

Intermediate-Size Patient Population Expanded Access Program for Intravenous Difelikefalin

NCT03636269Phase 3CompletedPrimary

CR845-CLIN3103: A Global Study to Evaluate the Safety and Efficacy of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus

NCT03422653Phase 3CompletedPrimary

A Study to Evaluate the Safety and Efficacy of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus (KALM-1)

NCT01660243Phase 2TerminatedPrimary

Efficacy and Safety of MT-9938 for Treatment of Uremic Pruritus in Subjects With End-stage Renal Disease Receiving Hemodialysis

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