Key Insights

Highlights

Success Rate

67% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 37/100

Termination Rate

9.1%

1 terminated out of 11 trials

Success Rate

66.7%

-19.8% vs benchmark

Late-Stage Pipeline

9%

1 trials in Phase 3/4

Results Transparency

200%

4 of 2 completed with results

Key Signals

4 with results67% success

Data Visualizations

Phase Distribution

11Total
P 1 (6)
P 2 (4)
P 3 (1)

Trial Status

Active Not Recruiting4
Completed2
Recruiting2
Terminated1
Withdrawn1
Not Yet Recruiting1

Trial Success Rate

66.7%

Benchmark: 86.5%

Based on 2 completed trials

Clinical Trials (12)

Showing 12 of 12 trials
NCT07576725Phase 2Not Yet Recruiting

Low Dose, Reduced Frequency Nivolumab for the Treatment of Unresectable or Metastatic Cancer, AFFORD IO Trial

NCT01468896Phase 1Active Not Recruiting

Cetuximab and Recombinant Interleukin-12 in Treating Patients With Squamous Cell Carcinoma of the Head and Neck That is Recurrent, Metastatic, or Cannot Be Removed by Surgery

NCT04534205Phase 2RecruitingPrimary

A Clinical Trial Investigating the Safety, Tolerability, and Therapeutic Effects of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Alone for Patients With a Form of Head and Neck Cancer Positive for Human Papilloma Virus 16 and Expressing the Protein PD-L1

NCT07156227Phase 1Not Yet Recruiting

Testing the Addition of an Anti-Cancer Drug, Camonsertib, to Radiation Therapy for Recurrent Head and Neck Squamous Cell Carcinoma

NCT05269381Phase 1Recruiting

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

NCT03468218Phase 2Active Not Recruiting

Pembrolizumab & Cabozantinib in Patients With Head and Neck Squamous Cell Cancer

NCT06790966Phase 3Active Not Recruiting

Phase 3 Study of PDS0101 and Pembrolizumab in HPV16+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

NCT04576091Phase 1Active Not Recruiting

Testing the Addition of an Anti-cancer Drug, BAY 1895344, With Radiation Therapy to the Usual Pembrolizumab Treatment for Recurrent Head and Neck Cancer

NCT04870840Phase 1Completed

Image-guided Proton Therapy for the Treatment of Locally Advanced Unresectable Head and Neck Cancer

NCT03229278Phase 1Completed

Trigriluzole With Nivolumab and Pembrolizumab in Treating Patients With Metastatic or Unresectable Solid Malignancies or Lymphoma

NCT04834349Phase 2Withdrawn

Re-irradiation With NBTXR3 in Combination With Pembrolizumab for the Treatment of Inoperable Locoregional Recurrent Head and Neck Squamous Cell Cancer

NCT03823131Phase 2Terminated

Optimizing Antitumor Immunity Using Plasmid Electroporation, Pembrolizumab, and Epacadostat

Showing all 12 trials

Research Network

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