Treatment Resistant Depression (TRD)
25
12
12
4
Key Insights
Highlights
Success Rate
80% trial completion
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 49/100
4.0%
1 terminated out of 25 trials
80.0%
-6.6% vs benchmark
8%
2 trials in Phase 3/4
50%
2 of 4 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.6%
Based on 4 completed trials
Clinical Trials (25)
Ketogenic Diet and Neuromodulation in Treatment Resistant Depression
Lumateperone for Late-Life Depression
Treatment Resistance in Psychiatric Disorders: the Search for Biological Markers Predictive of Response to Treatment
Coaching as an Adjunct to Ketamine Therapy for Treatment-Resistant Depression
A Randomized, Double-Blind Controlled Comparison of NRX-101 vs. Placebo for Adults Being Treated With Robotic Transcranial Magnetic Stimulation for Treatment Resistant Depression: The SPARC-TMS Trial
Treatment Resistant Depression and Vagus Nerve Stimulation
Accelerated Transcranial Magnetic Stimulation in Treatment-Resistant Depressed Patients
Accelerated iTBS for Major Depression
Maintenance TMS in Treatment Resistant Depression
Algorithm Guided Treatment Versus Treatment as Usual (TAU) for Patients With Treatment Resistant Depression
Ketamine-Assisted Psychotherapy for Treatment-Resistant Depression
Esketamine Nasal Spray in Real-World Settings in Treatment-Resistant Depression
Neuronavigated aiTBS for TRD
Spaced Transcranial Direct Current Stimulation for Treatment-Resistant Depression: A Home-Based Feasibility and Safety Study
Electroconvulsive Therapy Augmented With Transcranial Magnetic Stimulation for Treatment Resistant Depression
Ketamine Biomarker Validation
Parcel-guided rTMS for Major Depressive Disorder
Feasibility Trial of Exercise as a Priming Strategy for rTMS Treatment in Difficult-to-Treat Depression
Comparison of the Efficacy of Accelerated Intermittent Theta Burst Stimulation and Accelerated Continuous Theta Burst Stimulation in Patients With Treatment-Resistant Depression
Intravenous Ketamine for Treatment-Resistant Depression