Key Insights

Highlights

Success Rate

50% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 65/100

Termination Rate

23.1%

3 terminated out of 13 trials

Success Rate

50.0%

-36.5% vs benchmark

Late-Stage Pipeline

23%

3 trials in Phase 3/4

Results Transparency

67%

2 of 3 completed with results

Key Signals

2 with results50% success

Data Visualizations

Phase Distribution

7Total
Not Applicable (2)
P 2 (2)
P 3 (3)

Trial Status

Terminated3
Unknown3
Completed3
Recruiting2
Active Not Recruiting1
Not Yet Recruiting1

Trial Success Rate

50.0%

Benchmark: 86.5%

Based on 3 completed trials

Clinical Trials (13)

Showing 13 of 13 trials
NCT04543591Phase 3CompletedPrimary

Ravulizumab in Thrombotic Microangiopathy After Hematopoietic Stem Cell Transplant

NCT07347990Not ApplicableNot Yet RecruitingPrimary

Safety and Efficacy of Iptacopan in Patients With High-Risk Transplantation-Associated Thrombotic Microangiopathy

NCT04557735Phase 3CompletedPrimary

Study of Ravulizumab in Pediatric Participants With HSCT-TMA

NCT07279610Phase 2Active Not RecruitingPrimary

N-Acetylcysteine as Therapy for Transplantation- Associated Thrombotic Microangiopathy

NCT04777435Not ApplicableRecruitingPrimary

Therapeutic Orientation Test in Thrombotic Microangiopathy

NCT07059026RecruitingPrimary

Thrombotic Microangiopathy (TMA) Associated With Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) In Adult Patients

NCT04743804Phase 3TerminatedPrimary

Ravulizumab in Thrombotic Microangiopathy Associated With a Trigger

NCT05991245UnknownPrimary

French National Cohort MATRIX "Renal and Systemic Thrombotic Microangiopathy"

NCT04845022Unknown

Incidence of Snakebite Associated Thrombotic Microangiopathy & Role of Peripheral Blood Smear as a Predictor of Clinical Outcome

NCT02604420CompletedPrimary

Identification and Treatment of Thrombotic Microangiopathies in Allogeneic Stem Cell Transplants

NCT02355782UnknownPrimary

OMS721 Compassionate Use in Patients With Thrombotic Microangiopathy

NCT00593229TerminatedPrimary

International Registry and Biorepository for TMA(Thrombotic Microangiopathy)

NCT00726544Phase 2TerminatedPrimary

Clinical Outcome Study of ARC1779 Injection in Patients With Thrombotic Microangiopathy

Showing all 13 trials

Research Network

Activity Timeline