Key Insights

Highlights

Success Rate

63% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 64/100

Termination Rate

21.4%

3 terminated out of 14 trials

Success Rate

62.5%

-24.1% vs benchmark

Late-Stage Pipeline

21%

3 trials in Phase 3/4

Results Transparency

40%

2 of 5 completed with results

Key Signals

2 with results63% success

Data Visualizations

Phase Distribution

7Total
Not Applicable (2)
P 2 (2)
P 3 (3)

Trial Status

Completed5
Unknown3
Terminated3
Recruiting1
Active Not Recruiting1
Not Yet Recruiting1

Trial Success Rate

62.5%

Benchmark: 86.6%

Based on 5 completed trials

Clinical Trials (14)

Showing 14 of 14 trials
NCT07732361CompletedPrimary

A Study Using Real-world Data to Examine Outcomes in Children and Adults Who Develop a Blood Clotting Disorder Called Thrombotic Microangiopathy (TMA) After Undergoing a Hematopoietic Stem Cell Transplant (HSCT).

NCT04543591Phase 3CompletedPrimary

Ravulizumab in Thrombotic Microangiopathy After Hematopoietic Stem Cell Transplant

NCT04777435Not ApplicableCompletedPrimary

Therapeutic Orientation Test in Thrombotic Microangiopathy

NCT07347990Not ApplicableNot Yet RecruitingPrimary

Safety and Efficacy of Iptacopan in Patients With High-Risk Transplantation-Associated Thrombotic Microangiopathy

NCT04557735Phase 3CompletedPrimary

Study of Ravulizumab in Pediatric Participants With HSCT-TMA

NCT07279610Phase 2Active Not RecruitingPrimary

N-Acetylcysteine as Therapy for Transplantation- Associated Thrombotic Microangiopathy

NCT07059026RecruitingPrimary

Thrombotic Microangiopathy (TMA) Associated With Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) In Adult Patients

NCT04743804Phase 3TerminatedPrimary

Ravulizumab in Thrombotic Microangiopathy Associated With a Trigger

NCT05991245UnknownPrimary

French National Cohort MATRIX "Renal and Systemic Thrombotic Microangiopathy"

NCT04845022Unknown

Incidence of Snakebite Associated Thrombotic Microangiopathy & Role of Peripheral Blood Smear as a Predictor of Clinical Outcome

NCT02604420CompletedPrimary

Identification and Treatment of Thrombotic Microangiopathies in Allogeneic Stem Cell Transplants

NCT02355782UnknownPrimary

OMS721 Compassionate Use in Patients With Thrombotic Microangiopathy

NCT00593229TerminatedPrimary

International Registry and Biorepository for TMA(Thrombotic Microangiopathy)

NCT00726544Phase 2TerminatedPrimary

Clinical Outcome Study of ARC1779 Injection in Patients With Thrombotic Microangiopathy

Showing all 14 trials

Research Network

Activity Timeline