Key Insights

Highlights

Success Rate

92% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

4.2%

1 terminated out of 24 trials

Success Rate

92.3%

+5.8% vs benchmark

Late-Stage Pipeline

4%

1 trials in Phase 3/4

Results Transparency

33%

4 of 12 completed with results

Key Signals

4 with results92% success

Data Visualizations

Phase Distribution

18Total
Not Applicable (5)
Early P 1 (3)
P 1 (4)
P 2 (5)
P 3 (1)

Trial Status

Completed12
Recruiting8
Unknown2
Withdrawn1
Terminated1

Trial Success Rate

92.3%

Benchmark: 86.5%

Based on 12 completed trials

Clinical Trials (24)

Showing 20 of 20 trials
NCT06303921Early Phase 1RecruitingPrimary

Study of Biodistribution, Metabolism, Excretion and Brain Uptake11C-M503

NCT05508789Phase 3Recruiting

A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 5)

NCT05318976Phase 2Completed

A Study of XPro1595 in Patients With Early Alzheimer's Disease With Biomarkers of Inflammation

NCT05522387Phase 2Terminated

An Open-Label Extension of XPro1595 in Patients With Alzheimer's Disease

NCT06083467Not ApplicableRecruitingPrimary

CW2IP2: Imaging and Diagnostic Assessments

NCT05427448Not ApplicableCompleted

Validation of Blood Biomarkers for Alzheimer's Disease

NCT07306598Recruiting

[18F]NIDF PET Imaging in Tau-related Diseases

NCT06932809Early Phase 1RecruitingPrimary

Study of Biodistribution, Metabolism, Excretion and Brain Uptake 18F-JSS20-183A

NCT06032026Early Phase 1RecruitingPrimary

Study of Biodistribution, Metabolism, Excretion and Brain Uptake of 11C-HY-2-15

NCT04445831Phase 1Completed

A Study to Evaluate the Safety, Tolerability and Immunogenicity of Tau Targeted Vaccines in Participants With Early Alzheimer's Disease

NCT05080777Not ApplicableCompleted

Pilot Pragmatic Clinical Trial to Embed Tele-Savvy Into Health Care Systems

NCT06690983RecruitingPrimary

Tau PET/CT in Various Tau-Related Disease Patients

NCT06596746Recruiting

Neurodegenerative Diseases Progression Markers (MARKERS-NDD)

NCT03938870Completed

CNS Tau Kinetics in Healthy Aging and Alzheimer's Disease

NCT05202223Not ApplicableCompleted

Harmony at Home: A Pilot Telehealth Program for Rural ADRD Caregivers

NCT05321498Phase 2Withdrawn

Study to Assess the Efficacy of XPro1595 in Patients With Mild Cognitive Impairment With Biomarkers of Inflammation

NCT05344989Phase 1Unknown

A First-in-Human Study to Assess Single Doses of APNmAb005 in Healthy Participants

NCT05527288Not ApplicableCompleted

A Bridging Study on Efficacy and Safety of [18F]Florbetaben PET for Diagnosis of Alzheimer Disease Subjects in Chinese Population

NCT03538522Phase 2Completed

A Double-Blind, Placebo-Controlled Safety and Efficacy Study of NA-831

NCT02676843Phase 2Completed

Tau PET Imaging With 18F-AV-1451 in Subjects With MAPT Mutations

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Research Network

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