Key Insights

Highlights

Success Rate

57% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 60/100

Termination Rate

10.7%

3 terminated out of 28 trials

Success Rate

57.1%

-29.4% vs benchmark

Late-Stage Pipeline

7%

2 trials in Phase 3/4

Results Transparency

100%

4 of 4 completed with results

Key Signals

4 with results57% success

Data Visualizations

Phase Distribution

28Total
Not Applicable (6)
P 1 (12)
P 2 (8)
P 3 (1)
P 4 (1)

Trial Status

Recruiting14
Active Not Recruiting6
Completed4
Terminated3
Suspended1

Trial Success Rate

57.1%

Benchmark: 86.5%

Based on 4 completed trials

Clinical Trials (28)

Showing 20 of 20 trials
NCT06811116Phase 1Recruiting

Testing the Addition of an Anti-cancer Drug, Sapanisertib, to the Usual Chemotherapy Treatment (Cabozantinib) in Metastatic Liver Cell Cancer With a Change in Genes for the Protein β-Catenin, The SAPHIRE Trial

NCT04175912Phase 2Active Not Recruiting

Testing the Combination of Pevonedistat With Chemotherapy for Bile Duct Cancer of the Liver

NCT03695250Phase 1Terminated

BMS-986205 and Nivolumab as First or Second Line Therapy in Treating Patients With Liver Cancer

NCT05092373Phase 1Recruiting

Phase I Study of Tumor Treating Fields (TTF) in Combination With Cabozantinib or With Pembrolizumab and Nab-Paclitaxel in Patients With Advanced Solid Tumors Involving the Abdomen or Thorax

NCT03942328Phase 1Recruiting

Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) Combined With Immune Checkpoint Inhibition After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer

NCT07166406Phase 3Recruiting

Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial

NCT07042919Phase 1Recruiting

Zanzalintinib in Second Line and Beyond for the Treatment of Advanced Liver Cancer

NCT05269381Phase 1Recruiting

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

NCT06968195Phase 1Suspended

Autologous CAR T Cells Targeting GPC3 (RPCAR01) for the Treatment of Advanced or Metastatic GPC3 Expressing Hepatocellular Carcinoma

NCT05038254Not ApplicableActive Not Recruiting

Enhanced Outpatient Symptom Management to Reduce Acute Care Visits Due to Chemotherapy-Related Adverse Events

NCT07405086Phase 4Recruiting

Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study

NCT03823144Not ApplicableRecruiting

Intravital Microscopy in Human Solid Tumors

NCT05791448Phase 1Recruiting

AU409 for the Treatment of Advanced Primary Liver Cancers or Solid Tumor With Liver Metastatic Disease

NCT04514484Phase 1Active Not Recruiting

Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV

NCT03896646Not ApplicableActive Not Recruiting

Radioembolization for HCC Patients With Personalized Yttrium-90 Dosimetry for Curative Intent (RAPY90D)

NCT05103904Phase 2Terminated

Lenvatinib for the Treatment of Recurrent Hepatocellular Carcinoma After Liver Transplant

NCT03655002Phase 1Active Not Recruiting

IRX-2, Cyclophosphamide, and Nivolumab in Treating Patients With Recurrent or Metastatic and Refractory Liver Cancer

NCT04605731Phase 1Active Not Recruiting

Durvalumab and Tremelimumab After Radioembolization for the Treatment of Unresectable, Locally Advanced Liver Cancer

NCT04380545Phase 1Recruiting

Nivolumab, Fluorouracil, and Interferon Alpha 2B for the Treatment of Unresectable Fibrolamellar Cancer

NCT05176223Phase 2Completed

68Ga PSMA PET Imaging for the Treatment of Advanced Liver Cancer

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