Key Insights

Highlights

Success Rate

75% trial completion

Published Results

27 trials with published results (52%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 37/100

Termination Rate

15.4%

8 terminated out of 52 trials

Success Rate

75.0%

-11.5% vs benchmark

Late-Stage Pipeline

12%

6 trials in Phase 3/4

Results Transparency

113%

27 of 24 completed with results

Key Signals

27 with results75% success

Data Visualizations

Phase Distribution

49Total
Not Applicable (1)
P 1 (22)
P 2 (20)
P 3 (6)

Trial Status

Completed24
Active Not Recruiting13
Terminated8
Recruiting4
Withdrawn2
Suspended1

Trial Success Rate

75.0%

Benchmark: 86.5%

Based on 24 completed trials

Clinical Trials (52)

Showing 20 of 20 trials
NCT02498613Phase 2Active Not Recruiting

A Phase 2 Study of Cediranib in Combination With Olaparib in Advanced Solid Tumors

NCT02311933Phase 2Active Not Recruiting

Tamoxifen Citrate or Z-Endoxifen Hydrochloride in Treating Patients With Locally Advanced or Metastatic, Estrogen Receptor-Positive, HER2-Negative Breast Cancer

NCT03633331Phase 2Completed

Palbociclib and Letrozole or Fulvestrant in Treating Patients With Estrogen Receptor Positive, HER2 Negative Metastatic Breast Cancer

NCT01552434Phase 1Active Not Recruiting

Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease

NCT02398773Phase 2Active Not Recruiting

FES PET/CT in Predicting Response in Patients With Newly Diagnosed Metastatic Breast Cancer Receiving Endocrine Therapy

NCT02713269Phase 2Active Not Recruiting

Thermal Ablation and Spine Stereotactic Radiosurgery in Treating Patients With Spine Metastases at Risk for Compressing the Spinal Cord

NCT01327781Phase 1Active Not Recruiting

Z-Endoxifen Hydrochloride in Treating Patients With Metastatic or Locally Recurrent Estrogen Receptor-Positive Breast Cancer

NCT01351909Phase 1Active Not Recruiting

Cyclophosphamide and Veliparib in Treating Patients With Locally Advanced or Metastatic Breast Cancer

NCT02595905Phase 2Completed

Cisplatin With or Without Veliparib in Treating Patients With Recurrent or Metastatic Triple-Negative and/or BRCA Mutation-Associated Breast Cancer With or Without Brain Metastases

NCT02778685Phase 2Active Not Recruiting

Pembrolizumab, Endocrine Therapy, and Palbociclib in Treating Postmenopausal Patients With Newly Diagnosed Metastatic Stage IV Estrogen Receptor Positive Breast Cancer

NCT03101748Phase 1Terminated

Neratinib and Paclitaxel With or Without Pertuzumab and Trastuzumab Before Combination Chemotherapy in Treating Patients With Metastatic or Locally Advanced Breast Cancer

NCT05334069Recruiting

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

NCT04692103Phase 2Active Not Recruiting

Serial FES PET/CT to Measure Hormone Expression in Patients Undergoing Endocrine Targeted Therapy

NCT04521764Phase 1Recruiting

A Vaccine (MV-s-NAP) for the Treatment of Patients With Invasive Metastatic Breast Cancer

NCT02208375Phase 1Active Not Recruiting

mTORC1/2 Inhibitor AZD2014 or the Oral AKT Inhibitor AZD5363 for Recurrent Endometrial and Ovarian

NCT03199885Phase 3Completed

Testing the Drug Atezolizumab or Placebo With Usual Therapy in First-Line HER2-Positive Metastatic Breast Cancer

NCT01251874Phase 1Active Not Recruiting

Veliparib and Carboplatin in Treating Patients With HER2-Negative Metastatic Breast Cancer

NCT03418961Phase 3Recruiting

S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

NCT01463072Phase 2Active Not Recruiting

Nab-Paclitaxel in Treating Older Patients With Locally Advanced or Metastatic Breast Cancer

NCT03106415Phase 1Completed

Pembrolizumab and Binimetinib in Treating Patients With Locally Advanced or Metastatic Triple Negative Breast Cancer

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Research Network

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