Key Insights

Highlights

Success Rate

54% trial completion

Published Results

12 trials with published results (18%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 60/100

Termination Rate

16.4%

11 terminated out of 67 trials

Success Rate

54.2%

-32.4% vs benchmark

Late-Stage Pipeline

9%

6 trials in Phase 3/4

Results Transparency

92%

12 of 13 completed with results

Key Signals

12 with results54% success11 terminated

Data Visualizations

Phase Distribution

62Total
Not Applicable (16)
Early P 1 (2)
P 1 (21)
P 2 (17)
P 3 (6)

Trial Status

Active Not Recruiting25
Completed13
Recruiting12
Terminated11
Withdrawn5
Unknown1

Trial Success Rate

54.2%

Benchmark: 86.6%

Based on 13 completed trials

Clinical Trials (67)

Showing 20 of 20 trials
NCT04267848Phase 3Recruiting

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

NCT03939481Active Not Recruiting

Treatment Effects on Development of Chemotherapy-Induced Peripheral Neuropathy in Patients With Cancer

NCT06918132Phase 2Recruiting

Cemiplimab and Fianlimab Before Surgery for the Treatment of Stage IB-IIIB Non-Small Cell Lung Cancer

NCT06498635Phase 3Recruiting

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

NCT02194738Not ApplicableActive Not Recruiting

Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)

NCT04092283Phase 3Active Not Recruiting

Testing the Addition of an Antibody to Standard Chemoradiation Followed by the Antibody for One Year to Standard Chemoradiation Followed by One Year of the Antibody in Patients With Unresectable Stage III Non-Small Cell Lung Cancer

NCT06732401Phase 3Active Not Recruiting

Testing the Addition of AZD6738 (Ceralasertib) to Immunotherapy to Increase Time Without Cancer for Patients With Non-Small Cell Lung Cancer

NCT05017025Phase 1Completed

Aurora Kinase Inhibitor LY3295668 in Combination With Osimertinib for the Treatment of Advanced or Metastatic EGFR-Mutant Non-squamous Non-small Cell Lung Cancer

NCT05010109Not ApplicableRecruiting

Cardiovascular Injury and Cardiac Fitness in Locally Advanced Non-Small Cell Lung Cancer Patients Receiving Model Based Personalized Chemoradiation

NCT04940299Phase 2Active Not Recruiting

Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma

NCT04013542Phase 1Active Not Recruiting

Ipilimumab and Nivolumab in Combination With Radiation Therapy in Treating Patients With Stage 2-3 Non-small Lung Cancer

NCT04892953Phase 2Recruiting

Local Consolidative Therapy and Durvalumab for Oligoprogressive and Polyprogressive Stage III NSCLC After Chemoradiation and Anti-PD-L1 Therapy

NCT06632327Phase 3Active Not Recruiting

Comparing Impact of Treatment Before or After Surgery in Patients With Stage II-IIIB Resectable Non-small Cell Lung Cancer

NCT04073745Phase 1Active Not Recruiting

Single Fraction Stereotactic Body Radiation Therapy After Surgery in Treating Patients With Non-small Cell Lung Cancer

NCT05269381Phase 1Recruiting

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

NCT04505267Phase 1Active Not Recruiting

NBTXR3 and Radiation Therapy for the Treatment of Inoperable Recurrent Non-small Cell Lung Cancer

NCT04819997Not ApplicableActive Not Recruiting

A Nurse-Led Intervention for Fear of Progression in Advanced Cancer

NCT02955290Phase 1Active Not Recruiting

CIMAvax Vaccine, Nivolumab, and Pembrolizumab in Treating Patients With Advanced Non-small Cell Lung Cancer or Squamous Head and Neck Cancer

NCT03776253Not ApplicableCompleted

Conquer Fear SUPPORT Intervention in Supporting Patients With Stage III-IV Lung or Gynecologic Cancer

NCT05334329Phase 1Active Not Recruiting

Genetically Engineered Natural Killer (NK) Cells With or Without Atezolizumab for the Treatment of Non-small Cell Lung Cancer Previously Treated With PD-1 and/or PD-L1 Immune Checkpoint Inhibitors

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