Key Insights

Highlights

Success Rate

69% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

15.6%

5 terminated out of 32 trials

Success Rate

68.8%

-17.8% vs benchmark

Late-Stage Pipeline

3%

1 trials in Phase 3/4

Results Transparency

45%

5 of 11 completed with results

Key Signals

5 with results69% success

Data Visualizations

Phase Distribution

30Total
Not Applicable (1)
Early P 1 (1)
P 1 (16)
P 2 (11)
P 3 (1)

Trial Status

Completed11
Recruiting9
Terminated5
Active Not Recruiting3
Not Yet Recruiting1
Enrolling By Invitation1

Trial Success Rate

68.8%

Benchmark: 86.5%

Based on 11 completed trials

Clinical Trials (32)

Showing 20 of 20 trials
NCT03625037Phase 1Active Not Recruiting

First-in-Human (FIH) Trial in Patients With Relapsed, Progressive or Refractory B-Cell Lymphoma

NCT05131022Phase 1Recruiting

A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

NCT07221500Phase 2Recruiting

A Study of NX-5948 in Adults With CLL/SLL Previously Treated With a Bruton's Tyrosine Kinase Inhibitor and a B-cell Lymphoma-2 Inhibitor (DAYBreak CLL-201)

NCT04488354Phase 1Completed

Long-term Follow-up Study for Patients Treated With CLBR001 CAR-T

NCT07030400RecruitingPrimary

Predictors of Health-Related QOL in Adults With CLL or Small Lymphocytic Lymphoma

NCT04830137Phase 1Recruiting

A Study of NX-2127 in Adults With Relapsed/Refractory B-cell Malignancies

NCT03547115Phase 1Terminated

A Study of Voruciclib Alone or in Combination With Venetoclax in Subjects With B-Cell Malignancies or AML

NCT07428707Early Phase 1Recruiting

Immune Profiling of CLL/SLL Treated With First-Line Pirtobrutinib

NCT04419519Phase 2Active Not Recruiting

Assessing Minimal Residual Disease by Next- Generation Sequencing to Minimize Exposure in People With CLL or SLL Who Have Been Treated With Venetoclax

NCT07024706Phase 2Not Yet Recruiting

Phase 2 Study of Disease Risk Mutation-Guided Finite Acalabrutinib+Venetoclax for Relapsed CLL Post-1L Finite cBTKi+BCL2i ± Obinutuzumab

NCT02966756Phase 2Recruiting

A Study of Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

NCT02362035Phase 1Completed

ACP-196 (Acalabrutinib) in Combination With Pembrolizumab, for Treatment of Hematologic Malignancies

NCT05168930Phase 2Recruiting

Zanubrutinib and Venetoclax in CLL (ZANU-VEN)

NCT05105841Phase 2Completed

Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax in Combination With Intravenous (IV) Obinutuzumab or Oral Ibrutinib in Adult Participants With Untreated Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

NCT06849713Phase 2Recruiting

Zanubrutinib, Obinutuzumab, and Sonrotoclax in Previously Untreated Patients With CLL or SLL

NCT04072458Phase 1Active Not Recruiting

A Clinical Trial of BP1002 in Patients With Advanced Lymphoid Malignancies

NCT06788639Recruiting

A Study of Patients With Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Treated With Lisocabtagene Maraleucel in the Post-Marketing Setting

NCT06762431Phase 1Enrolling By Invitation

Phase I/II Open-label Study Evaluating The Safety And Efficacy of Concomitant Administration of Anti-CD19 CAR T-cell Therapy and Lenalidomide in Refractory/Relapsed Chronic Lymphocytic Leukemia Patients.

NCT03788291Phase 2Completed

Acalabrutinib and High Frequency Low Dose Subcutaneous Rituximab in Patients With Previously Untreated Chronic Lymphocytic Leukemia / Small Lymphocytic Lymphoma

NCT04450069Phase 1Completed

CLBR001 and SWI019 in Patients With Relapsed / Refractory B-cell Malignancies

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