Key Insights

Highlights

Success Rate

67% trial completion

Published Results

17 trials with published results (17%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

15.7%

16 terminated out of 102 trials

Success Rate

67.3%

-19.2% vs benchmark

Late-Stage Pipeline

9%

9 trials in Phase 3/4

Results Transparency

52%

17 of 33 completed with results

Key Signals

17 with results67% success16 terminated

Data Visualizations

Phase Distribution

91Total
Not Applicable (8)
Early P 1 (1)
P 1 (41)
P 2 (32)
P 3 (9)

Trial Status

Completed33
Recruiting20
Terminated16
Unknown14
Active Not Recruiting12
Not Yet Recruiting4

Trial Success Rate

67.3%

Benchmark: 86.6%

Based on 33 completed trials

Clinical Trials (102)

Showing 20 of 20 trials
NCT04585750Phase 1Recruiting

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

NCT03662074Phase 2TerminatedPrimary

Subsequent Line Gemcitabine and Nivolumab in Treating Participants With Metastatic Small Cell Lung Cancer

NCT07006727Phase 1RecruitingPrimary

Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid Tumors

NCT06992609Phase 3Active Not RecruitingPrimary

Durvalumab After Chemoradiotherapy in Limited Stage Small Cell Lung Cancer.

NCT05616624Phase 1Terminated

ADI-PEG 20 in Combination With Gemcitabine and Docetaxel After Progression on Frontline Therapy in Non-small Cell and Small Cell Lung Cancers

NCT05882058Phase 2RecruitingPrimary

DAREON™-5: A Study to Test Whether Different Doses of BI 764532 Help People With Small Cell Lung Cancer or Other Neuroendocrine Cancers

NCT06131840Phase 1Recruiting

A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

NCT04199741Phase 1Recruiting

PET/CT Imaging of Small Cell Lung Cancer Using 89Zr-DFO-SC16.56

NCT07046923Phase 1Recruiting

A Study of LY4175408 in Participants With Advanced Cancer

NCT06501976Phase 2Active Not RecruitingPrimary

An Exploratory Study of Lurbinectedin With Radiotherapy in SCLC With Single-lesion Progression After First Course Treatment

NCT05683977Active Not RecruitingPrimary

A French Real-life Study: EvaluatioN of durvALumab Utilization and Effectiveness for First Line Extensive Stage Small Cell Lung Cancer.

NCT06957314Not ApplicableRecruiting

A Study of Hospital-at-Home for People Receiving Tarlatamab

NCT05419076Phase 2Recruiting

A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain

NCT07623642Phase 2Not Yet Recruiting

A Phase II Study of GV20-0251 in Combination With Anti-PD-1 Monoclonal Antibodies in Patients With Unresectable, Locally Advanced, or Metastatic Solid Tumors.

NCT04938817Phase 1Active Not RecruitingPrimary

Safety and Efficacy Study of Investigational Agents as Monotherapy or in Combination With Pembrolizumab (MK-3475) for the Treatment of Extensive-Stage Small Cell Lung Cancer (ES-SCLC) in Need of Second-Line Therapy (MK-3475-B98/KEYNOTE-B98)

NCT03735095Phase 1Completed

Endobronchial Ultrasound Guided Interstitial Photodynamic Therapy in Treating Patients With Locally Advanced Lung Cancer

NCT06799286Phase 1Active Not RecruitingPrimary

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of BMS-986489 in Chinese Participants With Relapsed/Refractory Small Cell Lung Cancer

NCT04902872Phase 1Completed

Study of CBX-12 in Subjects With Advanced or Metastatic Refractory Solid Tumors

NCT05617963Phase 2Active Not RecruitingPrimary

Durvalumab Maintenance After Thoracic Chemoradiotherapy in Frail Small Cell Lung Cancer Patients Whose Disease is Limited to the Thorax

NCT06586957Phase 1Recruiting

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

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