Key Insights

Highlights

Success Rate

80% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

4.8%

1 terminated out of 21 trials

Success Rate

80.0%

-6.5% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

0%

0 of 4 completed with results

Key Signals

80% success

Data Visualizations

Phase Distribution

14Total
Not Applicable (2)
Early P 1 (1)
P 1 (9)
P 2 (2)

Trial Status

Recruiting6
Not Yet Recruiting4
Completed4
Unknown3
Active Not Recruiting3
Terminated1

Trial Success Rate

80.0%

Benchmark: 86.5%

Based on 4 completed trials

Clinical Trials (21)

Showing 20 of 20 trials
NCT07237659Phase 1CompletedPrimary

Phase 1a/b Tolerability of NTR-1011 in Healthy Adults and Adult Patients With SLE and RA

NCT07516639Phase 1Not Yet Recruiting

First-in-Human Study of ISH0613: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics

NCT06150651Phase 1CompletedPrimary

Safety of PiggyBac Transposon CAR T-cells Targeting CD-19 in Refractory Lupus.

NCT06613360Phase 1Recruiting

A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Systemic Lupus Erythematosus

NCT07260877Phase 2Recruiting

A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 2a Study With an Open-Label Extension Evaluating the Efficacy and Safety of VENT-03 in Adult Participants With Active Cutaneous Lupus Erythematosus With or Without Systemic Lupus Erythematosus

NCT06548607Early Phase 1RecruitingPrimary

Clinical Study on Targeted CD19 or CD19-BCMA CAR-T Therapy for Autoimmune Diseases

NCT07196072Not ApplicableActive Not RecruitingPrimary

A Multi-component, Person-centered, and Yoga-based Coaching Program for Lupus Chronic Pain

NCT07364396Phase 1Not Yet Recruiting

Efficacy and Safety of CRC01 in Participants With Severe, Refractory Systemic Lupus Erythematosus

NCT06925542Phase 1RecruitingPrimary

A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease

NCT06294236Phase 1Active Not Recruiting

Study Evaluating SC291 in Subjects With Severe r/r B-cell Mediated Autoimmune Diseases (GLEAM)

NCT06971913Phase 2Not Yet RecruitingPrimary

Efficacy and Safety of Low-dose IL-2 in SLE Patients With CMV Viremia

NCT06445127TerminatedPrimary

Evaluation of Patients With Lupus Nephritis Using Kidney MRI (Magnetic Resonance Imaging)

NCT05866861Phase 1Active Not Recruiting

A Study in Participants With Mild-to-moderate Systemic Lupus Erythematosus

NCT06610409Not Yet RecruitingPrimary

Assessment of CXCL5 Level in SLE Patients and Its Correlation with Disease Activity

NCT06560775Not ApplicableCompletedPrimary

Effects of Nigella Sativa on T Cells and Cytokine Profile in Pediatric SLE Patients

NCT06063668UnknownPrimary

Autotaxin as Abiomarker in Systemic Lupus Erythematosus Patients

NCT06056921Phase 1RecruitingPrimary

Safety and Efficacy of CD19 Targeted CAR-T Therapy for Refractory Autoimmune Disease

NCT05624437CompletedPrimary

BElimumab corticoSteroids Sparing Treatment in Systemic Lupus Erythematosus

NCT04604990RecruitingPrimary

National Systemic Lupus Erythematosus Prospective Cohort, Saudi Arabia

NCT04866615UnknownPrimary

Posterior Segment Evaluation of Patients With SLE Using OCT and OCTA

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