Key Insights

Highlights

Success Rate

86% trial completion

Clinical Risk Assessment

Based on trial outcomes

Low Risk

Score: 27/100

Termination Rate

4.3%

1 terminated out of 23 trials

Success Rate

85.7%

-0.8% vs benchmark

Late-Stage Pipeline

22%

5 trials in Phase 3/4

Results Transparency

117%

7 of 6 completed with results

Key Signals

7 with results86% success

Data Visualizations

Phase Distribution

15Total
Not Applicable (5)
P 2 (5)
P 3 (1)
P 4 (4)

Trial Status

Not Yet Recruiting10
Completed6
Recruiting5
Active Not Recruiting1
Terminated1

Trial Success Rate

85.7%

Benchmark: 86.6%

Based on 6 completed trials

Clinical Trials (23)

Showing 20 of 20 trials
NCT07752043Not ApplicableNot Yet RecruitingPrimary

Standard of Care Comparative Arm of Phase 1/2 Gene Therapy Trial DREPAMIR" in Severe Sickle Cell Disease Patients

NCT07703566Not ApplicableNot Yet RecruitingPrimary

CPAP for Hypoxemic Acute Chest Syndrome in Sickle Cell Disease

NCT03814746Phase 3Active Not RecruitingPrimary

Study of Two Doses of Crizanlizumab Versus Placebo in Adolescent and Adult Sickle Cell Disease Patients

NCT07682662Phase 4Not Yet Recruiting

Low Dose Bolus Ketamine For Use In Sickle Cell Pain Crisis

NCT07532564Completed

Risk Factors, Costs, and Impacts of ED Boarding

NCT07639008Not Yet RecruitingPrimary

Epidemiology of Invasive Bacterial Infections in Children With Sickle Cell Disease in France Between 2020 and 2025

NCT06941389RecruitingPrimary

Comparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease

NCT06665997Phase 4RecruitingPrimary

Clinical and Biomarker Effects of Depot Medroxyprogesterone Acetate in Females With Sickle Cell Disease

NCT07540767Not ApplicableNot Yet Recruiting

Development of a Provider-Focused Intervention to Improve Health Outcomes in Pediatric Sickle Cell Disease

NCT07530965Not ApplicableNot Yet RecruitingPrimary

OMEGA-3-FATTY ACIDS IN CHILDREN WITH SICKLE CELL DISEASE

NCT07064174Recruiting

Sickle Cell Kidney Biorepository

NCT07488520Phase 4Not Yet RecruitingPrimary

Integrating Point of Care Testing (POCT) For Newborn Screening and Early Care for Sickle Cell Disease in Yopougon, Côte d'Ivoire

NCT03474965Phase 2CompletedPrimary

Study of Dose Confirmation and Safety of Crizanlizumab in Pediatric Sickle Cell Disease Patients

NCT04662931Phase 4CompletedPrimary

An Indian Multi-centric Phase IV Study to Assess the Safety of Crizanlizumab in Sickle Cell Disease Patients

NCT06619197Not ApplicableRecruitingPrimary

Exploratory Study on Global Reflexology in Sickle Cell Disease

NCT06850337Not Yet RecruitingPrimary

Megakaryocyte Heterogeneity in Sickle Cell Disease

NCT06887907RecruitingPrimary

Phenotypic and Transcriptomic Description of Megakaryocytes in Sickle Cell Patient

NCT06619093Not Yet RecruitingPrimary

Relationship Between Biological Phenotype, Clinical Severity of Sickle Cell Disease, and Blood Coagulation

NCT05565092Phase 2TerminatedPrimary

Safety, Efficacy, Pharmacokinetic, and Pharmacodynamic Study of ALXN1820 in Adult Participants With Sickle Cell Disease

NCT06761560Phase 2Not Yet RecruitingPrimary

Optimizing Hydroxyurea Dosage With Pharmakokinetic in Patients Suffering of Moderate to Severe Sickle Cell Anemia

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