Key Insights

Highlights

Success Rate

100% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Low Risk

Score: 5/100

Termination Rate

0.0%

0 terminated out of 21 trials

Success Rate

100.0%

+13.5% vs benchmark

Late-Stage Pipeline

57%

12 trials in Phase 3/4

Results Transparency

75%

9 of 12 completed with results

Key Signals

9 with results100% success

Data Visualizations

Phase Distribution

21Total
P 1 (1)
P 2 (8)
P 3 (12)

Trial Status

Completed12
Active Not Recruiting4
Withdrawn2
Recruiting2
Unknown1

Trial Success Rate

100.0%

Benchmark: 86.5%

Based on 12 completed trials

Clinical Trials (21)

Showing 20 of 20 trials
NCT06880770Phase 3RecruitingPrimary

Study of Plozasiran in Adults With Severe Hypertriglyceridemia at Risk of Acute Pancreatitis

NCT05355402Phase 2Completed

A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRx) in Adults With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease (Established or at Increased Risk for), and/or With Severe Hypertriglyceridemia

NCT07269210Phase 2RecruitingPrimary

A Study of Solbinsiran (LY3561774) in Participants With Severe Hypertriglyceridemia

NCT04720534Phase 2CompletedPrimary

Study to Evaluate ARO-APOC3 in Adults With Severe Hypertriglyceridemia

NCT05079919Phase 3CompletedPrimary

A Study of Olezarsen (ISIS 678354) Administered to Participants With Severe Hypertriglyceridemia

NCT06555640Phase 2CompletedPrimary

A Phase II Study to Evaluate the Efficacy and Safety of of DR10624 in Subjects With Severe Hypertriglyceridemia

NCT05681351Phase 3Active Not RecruitingPrimary

CORE-OLE: A Study of Olezarsen (ISIS 678354) Administered Subcutaneously to Participants With Severe Hypertriglyceridemia (SHTG)

NCT06347003Phase 3Active Not RecruitingPrimary

Study of Plozasiran (ARO-APOC3) in Adults With Severe Hypertriglyceridemia

NCT06347016Phase 3Active Not RecruitingPrimary

Study of Plozasiran in Adults With Severe Hypertriglyceridemia

NCT05552326Phase 3CompletedPrimary

A Study of Olezarsen Administered Subcutaneously to Participants With Severe Hypertriglyceridemia

NCT05852431Phase 3Active Not RecruitingPrimary

To Evaluate the Efficacy and Safety of Pegozafermin in Subjects With Severe Hypertriglyceridemia

NCT04541186Phase 2CompletedPrimary

Study to Explore the Efficacy and Safety of BIO89-100 (Pegozafermin) in Participants With Severe Hypertriglyceridemia

NCT03001817Phase 3CompletedPrimary

Study to Evaluate the Efficacy and Safety of K-877 in Adult Patients With Fasting High Triglyceride Levels and Normal Renal Function

NCT03011450Phase 3CompletedPrimary

Study to Evaluate the Efficacy and Safety of K-877 in Adult Patients With Fasting High Triglyceride Levels and Mild or Moderate Renal Impairment

NCT04662528Phase 3WithdrawnPrimary

Safety and Efficacy of MAT9001(Omega-3-pentaenoic Acid) in Subjects With Triglycerides ≥500 mg/dL and <2000 mg/dL

NCT02944383Phase 2CompletedPrimary

A 12-Week Study to Assess the Efficacy Safety and Tolerability of Gemcabene in Subjects With Severe Hypertriglyceridemia

NCT01997268Phase 3WithdrawnPrimary

The Efficacy of EPA+DHA (SC401B) for Lowering Triglyceride Levels (≥ 500 mg/dL)

NCT01242527Phase 2CompletedPrimary

Epanova® for Lowering Very High Triglycerides

NCT02189252Phase 1CompletedPrimary

An Open-Label Crossover Study to Compare the Relative Bioavailability, Efficacy and Safety of Epanova® and Lovaza® in Men and Women With a History of Pancreatitis

NCT01208961Phase 2CompletedPrimary

Epanova® Compared to Lovaza® In a Pharmacokinetic, Single-dose, Evaluation

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