Key Insights

Highlights

Success Rate

69% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

10.4%

5 terminated out of 48 trials

Success Rate

68.8%

-17.8% vs benchmark

Late-Stage Pipeline

8%

4 trials in Phase 3/4

Results Transparency

55%

6 of 11 completed with results

Key Signals

6 with results69% success

Data Visualizations

Phase Distribution

43Total
Not Applicable (3)
Early P 1 (1)
P 1 (20)
P 2 (15)
P 3 (4)

Trial Status

Recruiting17
Completed11
Active Not Recruiting7
Terminated5
Unknown4
Not Yet Recruiting2

Trial Success Rate

68.8%

Benchmark: 86.5%

Based on 11 completed trials

Clinical Trials (48)

Showing 20 of 20 trials
NCT07535359UnknownPrimary

Medical Access Program for Ifinatamab Deruxtecan in 3L+ Pretreated Extensive-stage Small Cell Lung Cancer

NCT04826341Phase 1Active Not Recruiting

A Phase I/II Study of Sacituzumab Govitecan Plus Berzosertib in Small Cell Lung Cancer, Extra-Pulmonary Small Cell Neuroendocrine Cancer and Homologous Recombination-Deficient Cancers Resistant to PARP Inhibitors

NCT05903092Phase 2Recruiting

MOnaliZumab in Combination With durvAlumab (MEDI4736) for tRreatmenT of Small Cell Lung Cancer

NCT07416695Phase 1RecruitingPrimary

A Phase I Clinical Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of HLX3901 in Patients With Advanced SCLC or NEC

NCT02734004Phase 1Active Not Recruiting

A Phase I/II Study of MEDI4736 in Combination With Olaparib in Patients With Advanced Solid Tumors.

NCT07508852Phase 1RecruitingPrimary

68Ga-PFD3 PET Imaging for the Diagnosis and Evaluation of Small Cell Lung Cancer

NCT04802174Phase 1Active Not RecruitingPrimary

Lurbinectedin With Berzosertib, an ATR Kinase Inhibitor in Small Cell Cancers and High-Grade Neuroendocrine Cancers

NCT04585750Phase 1Recruiting

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

NCT05546268Phase 1Active Not Recruiting

Study of Oral MRT-2359 in Selected Cancer Patients

NCT06657222Phase 1Recruiting

First in Human Study of TUB-030 in Patients With Advanced Solid Tumors

NCT07110103Phase 2RecruitingPrimary

Golidocitinib With PD-1 Inhibitors as Maintenance Treatment for Previously Untreated ES-SCLC

NCT05703269Not ApplicableRecruiting

Comparing Single vs Multiple Dose Radiation for Cancer Patients With Brain Metastasis and Receiving Immunotherapy

NCT06771219Phase 1Recruiting

SLV-154 Treatment of Metastatic Solid Tumors

NCT03575793Phase 1Completed

A Phase I/II Study of Nivolumab, Ipilimumab and Plinabulin in Patients With Recurrent Small Cell Lung Cancer

NCT04686682Phase 1Recruiting

A First-in-Human, JAB-8263 in Adult Patients With Advanced Tumors

NCT06021483RecruitingPrimary

Observational Study to Evaluate the Safety and Efficacy of Zepzelca™ Injection

NCT07145333Phase 2Active Not RecruitingPrimary

Pharmacogenomics ANDA SNP Clinical Study - Topotecan and Single Nucleotide Polymorphisms

NCT06179069Phase 1RecruitingPrimary

A Study of ZL-1310 in Subjects With Small Cell Lung Cancer

NCT02611024Phase 1Completed

Pharmacokinetic Study of Lurbinectedin in Combination With Irinotecan in Patients With Selected Solid Tumors

NCT05844150Phase 2Active Not RecruitingPrimary

A Study of PM8002 (Anti-PD-L1/VEGF) in Combination With Chemotherapy in Patients With ES-SCLC

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Research Network

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