Key Insights

Highlights

Success Rate

67% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

12.5%

6 terminated out of 48 trials

Success Rate

66.7%

-19.9% vs benchmark

Late-Stage Pipeline

10%

5 trials in Phase 3/4

Results Transparency

58%

7 of 12 completed with results

Key Signals

7 with results67% success

Data Visualizations

Phase Distribution

43Total
Not Applicable (3)
Early P 1 (1)
P 1 (19)
P 2 (15)
P 3 (5)

Trial Status

Recruiting14
Completed12
Active Not Recruiting7
Terminated6
Unknown4
Not Yet Recruiting3

Trial Success Rate

66.7%

Benchmark: 86.5%

Based on 12 completed trials

Clinical Trials (48)

Showing 20 of 20 trials
NCT06179069Phase 1RecruitingPrimary

A Study of ZL-1310 in Subjects With Small Cell Lung Cancer

NCT04826341Phase 1Completed

A Phase I/II Study of Sacituzumab Govitecan Plus Berzosertib in Small Cell Lung Cancer, Extra-Pulmonary Small Cell Neuroendocrine Cancer and Homologous Recombination-Deficient Cancers Resistant to PARP Inhibitors

NCT07625644Phase 3Not Yet Recruiting

BL-M14D1 Plus Atezolizumab vs Standard of Care in First-Line Extensive-Stage Small Cell Lung Cancer (BrenDeLL-Lung01)

NCT02734004Phase 1Active Not Recruiting

A Phase I/II Study of MEDI4736 in Combination With Olaparib in Patients With Advanced Solid Tumors.

NCT07416695Phase 1RecruitingPrimary

A Phase I Clinical Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of HLX3901 in Patients With Advanced SCLC or NEC

NCT04585750Phase 1Recruiting

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

NCT05130255Phase 1TerminatedPrimary

GD2-SADA:177Lu-DOTA Complex in Patients With Solid Tumors Known to Express GD2

NCT07508852Phase 1RecruitingPrimary

68Ga-PFD3 PET Imaging for the Diagnosis and Evaluation of Small Cell Lung Cancer

NCT07535359UnknownPrimary

Medical Access Program for Ifinatamab Deruxtecan in 3L+ Pretreated Extensive-stage Small Cell Lung Cancer

NCT06657222Phase 1Recruiting

First in Human Study of TUB-030 in Patients With Advanced Solid Tumors

NCT06616532Phase 3Active Not RecruitingPrimary

PM8002 in Combination With Paclitaxel Compared With Chemotherapy as Second-line Treatment in Small Cell Lung Cancer

NCT05903092Phase 2Recruiting

MOnaliZumab in Combination With durvAlumab (MEDI4736) for tRreatmenT of Small Cell Lung Cancer

NCT04802174Phase 1Active Not RecruitingPrimary

Lurbinectedin With Berzosertib, an ATR Kinase Inhibitor in Small Cell Cancers and High-Grade Neuroendocrine Cancers

NCT05546268Phase 1Active Not Recruiting

Study of Oral MRT-2359 in Selected Cancer Patients

NCT07110103Phase 2RecruitingPrimary

Golidocitinib With PD-1 Inhibitors as Maintenance Treatment for Previously Untreated ES-SCLC

NCT05703269Not ApplicableRecruiting

Comparing Single vs Multiple Dose Radiation for Cancer Patients With Brain Metastasis and Receiving Immunotherapy

NCT03575793Phase 1Completed

A Phase I/II Study of Nivolumab, Ipilimumab and Plinabulin in Patients With Recurrent Small Cell Lung Cancer

NCT04686682Phase 1Recruiting

A First-in-Human, JAB-8263 in Adult Patients With Advanced Tumors

NCT06021483RecruitingPrimary

Observational Study to Evaluate the Safety and Efficacy of Zepzelca™ Injection

NCT07145333Phase 2Active Not RecruitingPrimary

Pharmacogenomics ANDA SNP Clinical Study - Topotecan and Single Nucleotide Polymorphisms

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