Key Insights

Highlights

Success Rate

85% trial completion

Published Results

28 trials with published results (22%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

7.2%

9 terminated out of 125 trials

Success Rate

84.7%

-1.8% vs benchmark

Late-Stage Pipeline

6%

7 trials in Phase 3/4

Results Transparency

56%

28 of 50 completed with results

Key Signals

28 with results85% success

Data Visualizations

Phase Distribution

113Total
Not Applicable (10)
Early P 1 (1)
P 1 (63)
P 2 (32)
P 3 (5)
P 4 (2)

Trial Status

Completed50
Recruiting27
Active Not Recruiting16
Terminated9
Withdrawn9
Not Yet Recruiting8

Trial Success Rate

84.7%

Benchmark: 86.5%

Based on 50 completed trials

Clinical Trials (125)

Showing 20 of 20 trials
NCT06094101Phase 1Recruiting

Personalized Vaccination in Fusion+ Sarcoma Patients (PerVision)

NCT06441331Phase 1Recruiting

Phase I Trial to Determine the Dose and Evaluate the PK and Safety of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive Tumors

NCT02567435Phase 3Active Not Recruiting

Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma

NCT03054792Phase 1Enrolling By InvitationPrimary

Molecular-Functional Imaging of Hypoxia in Childhood Sarcomas

NCT04483778Phase 1Active Not Recruiting

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

NCT01871766Phase 2Active Not RecruitingPrimary

Risk-Adapted Focal Proton Beam Radiation and/or Surgery in Patients With Low, Intermediate and High Risk Rhabdomyosarcoma Receiving Standard or Intensified Chemotherapy

NCT00840047Phase 2Active Not Recruiting

Methionine PET/CT Studies In Patients With Cancer

NCT07514819Not ApplicableNot Yet Recruiting

Integration of Adaptive Proton Therapy in Pediatric Solid Tumors and Hodgkin's Lymphoma

NCT03050268Recruiting

Familial Investigations of Childhood Cancer Predisposition

NCT07054944Recruiting

Tumor-Lymph Node Mapping

NCT06796543Not ApplicableRecruiting

Targeted Oligometastatic Radiation in Pediatric and Young Adult Patients With Soft Tissue and Bone Sarcoma

NCT04796012Phase 1Recruiting

VITAS: Atezolizumab in Combination With Chemotherapy for Pediatric Relapsed/Refractory Solid Tumors

NCT04897321Phase 1Recruiting

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

NCT04308330Phase 1Recruiting

Vorinostat in Combination With Chemotherapy in Relapsed/Refractory Solid Tumors and CNS Malignancies

NCT02867592Phase 2Active Not Recruiting

Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors

NCT06541262Phase 1Recruiting

Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors

NCT07516353Not ApplicableNot Yet Recruiting

my.naviGATE: A Guide to After-Treatment Effects for Adolescents and Young Adults

NCT02945800Phase 2Completed

Nab-Paclitaxel and Gemcitabine for Recurrent/Refractory Sarcoma

NCT03478462Phase 1Active Not Recruiting

Dose Escalation Study of CLR 131 in Pediatric Relapsed/Refractory Malignant Tumors Including Neuroblastoma and Sarcomas

NCT06865664Phase 1RecruitingPrimary

FGFR4 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory Rhabdomyosarcoma

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