Key Insights

Highlights

Success Rate

85% trial completion

Published Results

28 trials with published results (22%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

7.0%

9 terminated out of 128 trials

Success Rate

84.7%

-1.8% vs benchmark

Late-Stage Pipeline

5%

7 trials in Phase 3/4

Results Transparency

56%

28 of 50 completed with results

Key Signals

28 with results85% success

Data Visualizations

Phase Distribution

115Total
Not Applicable (10)
Early P 1 (2)
P 1 (64)
P 2 (32)
P 3 (5)
P 4 (2)

Trial Status

Completed50
Recruiting29
Active Not Recruiting18
Withdrawn9
Terminated9
Not Yet Recruiting7

Trial Success Rate

84.7%

Benchmark: 86.5%

Based on 50 completed trials

Clinical Trials (128)

Showing 20 of 20 trials
NCT02567435Phase 3Active Not Recruiting

Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma

NCT07628634Early Phase 1Recruiting

Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors

NCT07734805Active Not Recruiting

Radiological Diagnosis of Pediatric Neck Swellings

NCT07466316Phase 3RecruitingPrimary

A Study Comparing Higher Dose Chemotherapy Over a Shorter Amount of Time to Lower Dose Chemotherapy Plus Maintenance Over a Longer Amount of Time in Patients With Newly Diagnosed Intermediate-Risk Rhabdomyosarcoma (IR RMS)

NCT04337177Phase 1Active Not Recruiting

Flavored, Oral Irinotecan VAL-413 (Orotecan®) Given With Temozolomide for Treatment of Recurrent Pediatric Solid Tumors

NCT02867592Phase 2Active Not Recruiting

Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors

NCT06865664Phase 1RecruitingPrimary

FGFR4 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory Rhabdomyosarcoma

NCT04299113Phase 1Active Not RecruitingPrimary

Mocetinostat With Vinorelbine in Children, Adolescents & Young Adults With Refractory and/or Recurrent Rhabdomyosarcoma

NCT06796543Not ApplicableRecruiting

Targeted Oligometastatic Radiation in Pediatric and Young Adult Patients With Soft Tissue and Bone Sarcoma

NCT06541262Phase 1Recruiting

Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors

NCT07514819Not ApplicableNot Yet Recruiting

Integration of Adaptive Proton Therapy in Pediatric Solid Tumors and Hodgkin's Lymphoma

NCT06625190Phase 1Recruiting

Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors

NCT03050268Recruiting

Familial Investigations of Childhood Cancer Predisposition

NCT00840047Phase 2Active Not Recruiting

Methionine PET/CT Studies In Patients With Cancer

NCT01871766Phase 2Active Not RecruitingPrimary

Risk-Adapted Focal Proton Beam Radiation and/or Surgery in Patients With Low, Intermediate and High Risk Rhabdomyosarcoma Receiving Standard or Intensified Chemotherapy

NCT06023641Phase 2RecruitingPrimary

Treatment of Newly Diagnosed Rhabdomyosarcoma Using Molecular Risk Stratification and Liposomal Irinotecan Based Therapy in Children With Intermediate and High Risk Disease

NCT04796012Phase 1Recruiting

VITAS: Atezolizumab in Combination With Chemotherapy for Pediatric Relapsed/Refractory Solid Tumors

NCT07172958Phase 1RecruitingPrimary

Selective Antigen Specific T Cells and CAR T Cells in Subjects With Relapsed/Refractory Embryonal Tumors (SABRE)

NCT04897321Phase 1Recruiting

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

NCT07584499Phase 1Recruiting

Phase I Study of Becotatug Vedotin for Safety and Efficacy in EGFR-Positive Pediatric Relapsed/Refractory or Metastatic Solid Tumors

Scroll to load more

Research Network

Activity Timeline