Key Insights

Highlights

Success Rate

100% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

0.0%

0 terminated out of 21 trials

Success Rate

100.0%

+13.5% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

13%

1 of 8 completed with results

Key Signals

1 with results100% success

Data Visualizations

Phase Distribution

12Total
Not Applicable (5)
P 1 (4)
P 2 (3)

Trial Status

Recruiting8
Completed8
Active Not Recruiting3
Unknown1
Enrolling By Invitation1

Trial Success Rate

100.0%

Benchmark: 86.5%

Based on 8 completed trials

Clinical Trials (21)

Showing 20 of 20 trials
NCT07529041Not ApplicableEnrolling By InvitationPrimary

Real-time Acoustic Biofeedback for Enhancing Fixation Stability: A Proof-of-concept Study to Improve Ophthalmic Imaging Diagnostic Quality

NCT05573984Active Not Recruiting

Natural History of PRPF31 Mutation-Associated Retinal Dystrophy

NCT06455826Phase 1Completed

MAD of IVT VP-001 in PRPF31 Mutation-Associated Retinal Dystrophy Subjects (Wallaby)

NCT07502664Recruiting

Development and Evaluation of Functional Visual Field and Navigation Endpoints in Moderate to Profound Inherited Retinal Disease (DEFINE-IRD)

NCT07085533RecruitingPrimary

Natural History Study of Inherited Retinal Diseases

NCT06852963Phase 1Recruiting

A Repeat-Dose, Open-Label, Two Arm Safety and Efficacy Study of Two Doses of VP-001 Administered Intravitreally in Participants With Confirmed PRPF31 Mutation-Associated Retinal Dystrophy, Including Participants Previously Treated With VP001

NCT06177977Not ApplicableRecruitingPrimary

SS-HH-OCT as a Novel Diagnostic Modality for Early-Onset Retinal Dystrophies (EORDs)

NCT06319872Phase 1Recruiting

The Effects of Disulfiram (Antabuse®) on Visual Acuity in Patients With Retinal Degeneration

NCT05294978RecruitingPrimary

EyeConic: Qualification for Cone-Optogenetics

NCT03853252Not ApplicableCompletedPrimary

iPS Cells of Patients for Models of Retinal Dystrophies

NCT06162585Active Not Recruiting

Non-Interventional Long Term Follow-up Study of Participants Previously Enrolled in the RESTORE Study

NCT06375239Recruiting

Observational Study to Assess Endpoint Operational Feasibility & Measurement Properties in Patients with Retinal Degeneration

NCT03592017Not ApplicableCompleted

Performance of Long-wavelength Autofluorescence Imaging

NCT02014389RecruitingPrimary

Evaluation of Objective Perimetry Using Chromatic Multifocal Pupillometer

NCT04945772Phase 2Completed

Efficacy and Safety of MCO-010 Optogenetic Therapy in Adults With Retinitis Pigmentosa [RESTORE]

NCT01546181CompletedPrimary

Retinal Imaging by Adaptive Optics in Healthy Eyes and During Retinal and General Diseases

NCT04123626Phase 1Active Not Recruiting

A Study to Evaluate the Safety and Tolerability of QR-1123 in Subjects With Autosomal Dominant Retinitis Pigmentosa Due to the P23H Mutation in the RHO Gene

NCT03843840Completed

Dual Wavelength OCT

NCT04855045Phase 2Unknown

An Open-label, Dose Escalation and Double-masked, Randomized, Controlled Trial Evaluating Safety and Tolerability of Sepofarsen in Children (<8 Years of Age) With LCA10 Caused by Mutations in the CEP290 Gene.

NCT02983305Not ApplicableCompletedPrimary

Optical Head-Mounted Display Technology for Low Vision Rehabilitation

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