Key Insights

Highlights

Success Rate

82% trial completion

Published Results

35 trials with published results (41%)

Clinical Risk Assessment

Based on trial outcomes

Low Risk

Score: 27/100

Termination Rate

10.6%

9 terminated out of 85 trials

Success Rate

82.4%

-4.2% vs benchmark

Late-Stage Pipeline

58%

49 trials in Phase 3/4

Results Transparency

83%

35 of 42 completed with results

Key Signals

35 with results82% success

Data Visualizations

Phase Distribution

69Total
P 1 (2)
P 2 (18)
P 3 (34)
P 4 (15)

Trial Status

Completed42
Active Not Recruiting14
Recruiting12
Terminated9
Withdrawn6
Not Yet Recruiting2

Trial Success Rate

82.4%

Benchmark: 86.5%

Based on 42 completed trials

Clinical Trials (85)

Showing 20 of 20 trials
NCT07161258Phase 2RecruitingPrimary

A Pharmacokinetics (PK), Pharmacodynamics (PD), Safety and Tolerability Study of Fenebrutinib in Children and Adolescents With Relapsing Multiple Sclerosis (RMS)

NCT05344469RecruitingPrimary

A NIS Evaluating Various Injectable and Oral Treatments in Patients With Relapsing Multiple Sclerosis

NCT06846281Phase 3RecruitingPrimary

Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.

NCT05147220Phase 3Active Not RecruitingPrimary

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)

NCT05156281Phase 3Active Not RecruitingPrimary

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)

NCT06433752RecruitingPrimary

A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)

NCT06617793Phase 1RecruitingPrimary

An Open-label Study to Assess the Safety, Efficacy, and Cellular Kinetics of YTB323 in Relapsing Multiple Sclerosis

NCT06847724Phase 3Active Not RecruitingPrimary

Comparative PK, PD, Efficacy, and Safety Assessment of the Proposed Ocrelizumab Biosimilar CYB704 and Ocrevus in Participants With Relapsing Multiple Sclerosis

NCT05877963Phase 3RecruitingPrimary

Study to Evaluate Safety, Efficacy and Pharmacokinetics (PK) of a Modified Regimen of Ublituximab

NCT07211633Phase 3Active Not RecruitingPrimary

A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety, Radiological and Clinical Effects of Subcutaneous Ublituximab in Participants With Relapsing Multiple Sclerosis (RMS)

NCT07483450Phase 4RecruitingPrimary

A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Ocrelizumab in Participants With Relapsing Multiple Sclerosis and Primary Progressive Multiple Sclerosis

NCT03650114Phase 3Active Not RecruitingPrimary

Long-term Safety, Tolerability and Effectiveness Study of Ofatumumab in Patients With Relapsing MS

NCT04586010Phase 3Active Not RecruitingPrimary

A Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Teriflunomide in Relapsing Multiple Sclerosis (RMS)

NCT05119569Phase 2Active Not RecruitingPrimary

A Study to Investigate the Efficacy of Fenebrutinib in Relapsing Multiple Sclerosis (RMS)

NCT06143514RecruitingPrimary

A Study Evaluating the Presence and Concentration of BRIUMVI™ (Ublituximab) in Breast Milk

NCT07220252Phase 2Not Yet RecruitingPrimary

Study to Assess Effects of Ublituximab in Pediatric Participants With Relapsing Forms of Multiple Sclerosis

NCT04353492Phase 3CompletedPrimary

An Open-label Study Evaluating Ofatumumab Treatment Effectiveness and PROs in Subjects With RMS Transitioning From Fumarate-based RMS Approved Therapies or Fingolimod to Ofatumumab

NCT04586023Phase 3Active Not RecruitingPrimary

Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Teriflunomide in Relapsing Multiple Sclerosis (RMS)

NCT05090033CompletedPrimary

Characterizing the Use of Ofatumumab in a Real World Setting

NCT06372145Phase 3Active Not RecruitingPrimary

A Study to Investigate Long-term Safety and Tolerability of Tolebrutinib in Participants With Multiple Sclerosis.

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