Key Insights

Highlights

Success Rate

22% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 65/100

Termination Rate

46.7%

7 terminated out of 15 trials

Success Rate

22.2%

-64.3% vs benchmark

Late-Stage Pipeline

13%

2 trials in Phase 3/4

Results Transparency

200%

4 of 2 completed with results

Key Signals

4 with results22% success

Data Visualizations

Phase Distribution

15Total
Not Applicable (1)
Early P 1 (1)
P 1 (11)
P 3 (2)

Trial Status

Terminated7
Recruiting4
Completed2
Unknown1
Withdrawn1

Trial Success Rate

22.2%

Benchmark: 86.5%

Based on 2 completed trials

Clinical Trials (15)

Showing 15 of 15 trials
NCT05787496Phase 1TerminatedPrimary

A Safety, Tolerability and Efficacy Study of NC525 in Subjects With Advanced Myeloid Neoplasms

NCT06812104Phase 1RecruitingPrimary

Clinical Trial of KK2845 in Patients With Relapsed or Refractory Acute Myeloid Leukemia

NCT04666649Phase 1CompletedPrimary

Pegcrisantaspase in Combination With Venetoclax for Treatment of Relapsed or Refractory Acute Myeloid Leukemia (R/R AML)

NCT02675452Phase 1Terminated

AMG 176 First in Human Trial in Participants With Relapsed or Refractory Multiple Myeloma and Participants With Relapsed or Refractory Acute Myeloid Leukemia

NCT05038800Phase 1TerminatedPrimary

A Study to Evaluate MK-0482 for Relapsed/Refractory Acute Myeloid Leukemia (AML) or Chronic Myelomonocytic Leukemia (CMML) (MK-0482-002)

NCT03765541Phase 3TerminatedPrimary

Dexamethasone in Refractory or First Relapsed Acute Myeloid Leukemia

NCT06879847Not ApplicableRecruitingPrimary

A Single-arm, Prospective Study of TBI + BUMEL As a Conditioning Regimen for Salvage HSCT in Patients with R/R AML

NCT05726110Phase 3RecruitingPrimary

Selinexor in Combination With HAD or CAG Rregimens in Relapsed or Refractory Acute Myeloid Leukemia

NCT03755154Phase 1TerminatedPrimary

Study of a New Intravenous Drug, Called S65487, in Patients With Acute Myeloid Leukemia, Non Hodgkin Lymphoma, Multiple Myeloma or Chronic Lymphocytic Leukemia

NCT04478695Phase 1TerminatedPrimary

Study of AMG 330 in Combination With Pembrolizumab in Adult With Relapsed or Refractory Acute Myeloid Leukemia

NCT04176393Phase 1CompletedPrimary

A China Bridging Study of Ivosidenib in r/r AML Subjects With an IDH1 Mutation

NCT05522192Phase 1RecruitingPrimary

Clinical Study of Mitoxantrone Hydrochloride Liposome Injection in Subjects With Acute Myeloid Leukemia

NCT04842370Phase 1UnknownPrimary

Evaluation of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of PHI 101 for the Treatment of AML

NCT02623582Early Phase 1TerminatedPrimary

CD123 Redirected Autologous T Cells for AML

NCT02215629Phase 1WithdrawnPrimary

Dose Escalation Study in Acute Myeloid or B-Cell Acute Lymphoblastic Leukemia

Showing all 15 trials

Research Network

Activity Timeline