Key Insights

Highlights

Success Rate

54% trial completion

Published Results

11 trials with published results (22%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 60/100

Termination Rate

12.0%

6 terminated out of 50 trials

Success Rate

53.8%

-32.7% vs benchmark

Late-Stage Pipeline

10%

5 trials in Phase 3/4

Results Transparency

157%

11 of 7 completed with results

Key Signals

11 with results54% success

Data Visualizations

Phase Distribution

48Total
Not Applicable (2)
P 1 (16)
P 2 (25)
P 3 (4)
P 4 (1)

Trial Status

Recruiting20
Active Not Recruiting13
Completed7
Terminated6
Withdrawn3
Not Yet Recruiting1

Trial Success Rate

53.8%

Benchmark: 86.5%

Based on 7 completed trials

Clinical Trials (50)

Showing 20 of 20 trials
NCT06589804Phase 3Recruiting

Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

NCT07405086Phase 4Recruiting

Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study

NCT05063552Phase 2Active Not Recruiting

Testing the Use of Investigational Drugs Atezolizumab and/or Bevacizumab With or Without Standard Chemotherapy in the Second-Line Treatment of Advanced-Stage Head and Neck Cancers

NCT04671667Phase 2RecruitingPrimary

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

NCT01468896Phase 1Active Not Recruiting

Cetuximab and Recombinant Interleukin-12 in Treating Patients With Squamous Cell Carcinoma of the Head and Neck That is Recurrent, Metastatic, or Cannot Be Removed by Surgery

NCT06662058Not ApplicableRecruiting

Remote Audiometry to Monitor for Treatment-Related Hearing Loss in Patients With H&N SCC Receiving Cisplatin and/or Radiation

NCT06980038Phase 2Recruiting

Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer

NCT07213934Phase 1Recruiting

Phase I/ II Trial Combining PD-1 Inhibition and Neoadjuvant Proton or Photon Radiation Therapy in Recurrent Head and Neck Squamous Cell Carcinoma

NCT07156227Phase 1Not Yet Recruiting

Testing the Addition of an Anti-Cancer Drug, Camonsertib, to Radiation Therapy for Recurrent Head and Neck Squamous Cell Carcinoma

NCT05172258Phase 2Active Not Recruiting

Testing the Addition of an Anti-cancer Drug, Ipatasertib, to the Usual Immunotherapy Treatment (Pembrolizumab) in Patients With Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck

NCT06064877Phase 3Recruiting

A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma

NCT05980000Phase 2Active Not Recruiting

Ramucirumab and Pembrolizumab vs Pembrolizumab Monotherapy in PD-L1 Positive Head and Neck Squamous-Cell Carcinoma

NCT06788990Phase 2Recruiting

FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

NCT04375384Phase 2Recruiting

Cetuximab After Immunotherapy for the Treatment of Head and Neck Squamous Cell Cancer

NCT04007744Phase 1Active Not Recruiting

Sonidegib and Pembrolizumab in Treating Patients With Advanced Solid Tumors

NCT05901545Phase 1Recruiting

Evaluating 111In Panitumumab for Nodal Staging in Head and Neck Cancer

NCT06868433Phase 1Recruiting

TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer

NCT07026474Phase 3RecruitingPrimary

Re-Radiochemotherapy and Pembrolizumab vs. Immuno(Chemo)Therapy for Locoregionally Recurrent PD-L1 Positive (CPS≥1) HNSCC

NCT06239220Phase 2Recruiting

PD-L1 t-haNK, NAI IL-15sa and Cetuximab for Recurrent, Metastatic HNSCC

NCT04290546Phase 1Completed

CIML NK Cell in Head & Neck Cancer

Scroll to load more

Research Network

Activity Timeline