Key Insights

Highlights

Success Rate

86% trial completion

Published Results

34 trials with published results (48%)

Research Maturity

55 completed trials (77% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

12.7%

9 terminated out of 71 trials

Success Rate

85.9%

-0.6% vs benchmark

Late-Stage Pipeline

7%

5 trials in Phase 3/4

Results Transparency

62%

34 of 55 completed with results

Key Signals

34 with results86% success

Data Visualizations

Phase Distribution

67Total
Not Applicable (7)
P 1 (30)
P 2 (25)
P 3 (5)

Trial Status

Completed55
Terminated9
Recruiting4
Active Not Recruiting1
Unknown1
Withdrawn1

Trial Success Rate

85.9%

Benchmark: 86.5%

Based on 55 completed trials

Clinical Trials (71)

Showing 20 of 20 trials
NCT06247787Phase 1RecruitingPrimary

A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapy

NCT01384513Phase 2Completed

A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies

NCT06609928Phase 1RecruitingPrimary

FH-FOLR1 Chimeric Antigen Receptor T Cell Therapy for Treating Pediatric Patients With Relapsed or Refractory Acute Myeloid Leukemia

NCT03326921Phase 1Recruiting

HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant

NCT01760655Phase 2Completed

Reduced-Intensity Conditioning Before Donor Stem Cell Transplant in With High-Risk Hematologic Malignancies

NCT00357565Phase 2Completed

Hematopoietic Stem Cell Transplantation in the Treatment of Infant Leukemia

NCT02094794Phase 2Active Not Recruiting

Total Marrow and Lymphoid Irradiation and Chemotherapy Before DSCT in Treating Patients With High-Risk ALL or AML

NCT05857969Phase 1RecruitingPrimary

Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling

NCT02446964Phase 1Completed

Total Marrow and Lymphoid Irradiation and Chemotherapy Before Donor Transplant in Treating Patients With Myelodysplastic Syndrome or Acute Leukemia

NCT02220985Phase 2Completed

Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD

NCT03537599Phase 1Terminated

Daratumumab and Donor Lymphocyte Infusion in Treating Participants With Relapsed Acute Myeloid Leukemia After Stem Cell Transplant

NCT01858740Phase 2Completed

Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts in Preventing GVHD in Children

NCT00540995Phase 1Terminated

Busulfan, Etoposide, and Intensity-Modulated Radiation Therapy Followed By Donor Stem Cell Transplant in Treating Patients With Advanced Myeloid Cancer

NCT02642965Phase 1Completed

Liposome-encapsulated Daunorubicin-Cytarabine, Fludarabine Phosphate, Cytarabine, and Filgrastim in Treating Younger Patients With Relapsed or Refractory Acute Myeloid Leukemia

NCT03860376CompletedPrimary

Ex Vivo Drug Sensitivity Testing and Mutation Profiling

NCT00119366Phase 2Terminated

Iodine I 131 Monoclonal Antibody BC8, Fludarabine Phosphate, Total Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients With Advanced Acute Myeloid Leukemia or Myelodysplastic Syndrome

NCT01640301Phase 1Terminated

Laboratory-Treated T Cells in Treating Patients With High-Risk Relapsed Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelogenous Leukemia Previously Treated With Donor Stem Cell Transplant

NCT01005277Completed

Study of Biomarkers in DNA Samples From Patients With Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia

NCT01817075Phase 3Completed

Chlorhexidine Gluconate Cleansing in Preventing Central Line Associated Bloodstream Infection and Acquisition of Multi-drug Resistant Organisms in Younger Patients With Cancer or Undergoing Donor Stem Cell Transplant

NCT00860574Phase 2Completed

Treosulfan, Fludarabine Phosphate, and Total-Body Irradiation Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Myelodysplastic Syndrome, Acute Lymphoblastic Leukemia

Scroll to load more

Research Network

Activity Timeline