Key Insights

Highlights

Success Rate

73% trial completion

Published Results

35 trials with published results (37%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 47/100

Termination Rate

17.9%

17 terminated out of 95 trials

Success Rate

73.4%

-13.1% vs benchmark

Late-Stage Pipeline

9%

9 trials in Phase 3/4

Results Transparency

74%

35 of 47 completed with results

Key Signals

35 with results73% success17 terminated

Data Visualizations

Phase Distribution

91Total
Not Applicable (5)
Early P 1 (3)
P 1 (48)
P 2 (26)
P 3 (9)

Trial Status

Completed47
Terminated17
Active Not Recruiting15
Recruiting8
Withdrawn4
Suspended2

Trial Success Rate

73.4%

Benchmark: 86.5%

Based on 47 completed trials

Clinical Trials (95)

Showing 20 of 20 trials
NCT02206334Phase 1Completed

Stereotactic Body Radiation Therapy in Treating Patients With Metastatic Breast Cancer, Non-small Cell Lung Cancer, or Prostate Cancer

NCT02465060Phase 2Active Not Recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

NCT02311933Phase 2Active Not RecruitingPrimary

Tamoxifen Citrate or Z-Endoxifen Hydrochloride in Treating Patients With Locally Advanced or Metastatic, Estrogen Receptor-Positive, HER2-Negative Breast Cancer

NCT02115282Phase 3Active Not Recruiting

Exemestane With or Without Entinostat in Treating Patients With Recurrent Hormone Receptor-Positive Breast Cancer That is Locally Advanced or Metastatic

NCT03939897Phase 1Active Not Recruiting

Testing the Addition of Copanlisib to Usual Treatment (Fulvestrant and Abemaciclib) in Metastatic Breast Cancer

NCT01552434Phase 1Active Not Recruiting

Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease

NCT03971409Phase 2Active Not Recruiting

Avelumab With Binimetinib, Sacituzumab Govitecan, or Liposomal Doxorubicin in Treating Stage IV or Unresectable, Recurrent Triple Negative Breast Cancer

NCT01351909Phase 1Active Not Recruiting

Cyclophosphamide and Veliparib in Treating Patients With Locally Advanced or Metastatic Breast Cancer

NCT04550494Phase 2Recruiting

Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations

NCT04052555Phase 1Active Not Recruiting

Testing the Addition of an Anti-cancer Drug, Berzosertib, to the Usual Treatment (Radiation Therapy) for Chemotherapy-Resistant Triple-Negative and Estrogen and/or Progesterone Receptor Positive, HER2 Negative Breast Cancer

NCT01327781Phase 1Active Not Recruiting

Z-Endoxifen Hydrochloride in Treating Patients With Metastatic or Locally Recurrent Estrogen Receptor-Positive Breast Cancer

NCT02595905Phase 2Completed

Cisplatin With or Without Veliparib in Treating Patients With Recurrent or Metastatic Triple-Negative and/or BRCA Mutation-Associated Breast Cancer With or Without Brain Metastases

NCT03987555Suspended

Paclitaxel Therapeutic Drug Monitoring in Cancer Patients

NCT03737695Suspended

Clinical Information and Biospecimen Collection From Patients With Recurrent or Stage IV Breast Cancer

NCT03725436Phase 1Completed

ALRN-6924 and Paclitaxel in Treating Patients With Advanced, Metastatic, or Unresectable Solid Tumors

NCT06704659Not ApplicableRecruitingPrimary

Study on Recurrent Breast Cancer and Repeated Radiation Therapy

NCT03941730Phase 2Active Not Recruiting

Estradiol in Treating Patients With ER Beta Positive, Triple Negative Locally Advanced or Metastatic Breast Cancer

NCT06217874Recruiting

Collection of Specimens and Clinical Data for Patients With Recurrent or Metastatic Breast Cancer or Male Breast Cancer

NCT02157051Phase 1Active Not Recruiting

Vaccine Therapy in Treating Patients With HER2-Negative Stage III-IV Breast Cancer

NCT00066690Phase 3Completed

Suppression of Ovarian Function With Either Tamoxifen or Exemestane Compared With Tamoxifen Alone in Treating Premenopausal Women With Hormone-Responsive Breast Cancer

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Research Network

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