Key Insights

Highlights

Success Rate

85% trial completion

Published Results

24 trials with published results (51%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 47/100

Termination Rate

12.8%

6 terminated out of 47 trials

Success Rate

85.4%

-1.1% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

69%

24 of 35 completed with results

Key Signals

24 with results85% success

Data Visualizations

Phase Distribution

45Total
Not Applicable (4)
Early P 1 (1)
P 1 (12)
P 2 (28)

Trial Status

Completed35
Terminated6
Withdrawn4
Active Not Recruiting1
Recruiting1

Trial Success Rate

85.4%

Benchmark: 86.5%

Based on 35 completed trials

Clinical Trials (47)

Showing 20 of 20 trials
NCT01552434Phase 1Active Not Recruiting

Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease

NCT02701153Not ApplicableRecruitingPrimary

Phase II Study of 5-Day Hypofractionated Preoperative Radiation Therapy for Soft Tissue Sarcomas: Expansion Cohort

NCT00638898Phase 1Completed

Busulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid Tumor

NCT01586104Not ApplicableCompleted

Intensity-Modulated Radiation Therapy in Treating Younger Patients With Lung Metastases

NCT01638533Phase 1Completed

Romidepsin in Treating Patients With Lymphoma, Chronic Lymphocytic Leukemia, or Solid Tumors With Liver Dysfunction

NCT05238831Early Phase 1Withdrawn

SMMART Adaptive Clinical Treatment (ACT) Trial

NCT00019968Phase 2Completed

Isolated Limb Perfusion of Melphalan With or Without Tumor Necrosis Factor in Treating Patients With Soft Tissue Sarcoma of the Arm or Leg

NCT00919269Completed

Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma

NCT03317457Phase 2Completed

Durvalumab and Tremelimumab Compared to Doxorubicin in Patients With Advanced or Metastatic Soft Tissue Sarcoma

NCT01462630Phase 2Completed

Pazopanib Hydrochloride in Treating Patients With Advanced Angiosarcoma

NCT02357810Phase 2Completed

Pazopanib Hydrochloride and Topotecan Hydrochloride in Treating Patients With Metastatic Soft Tissue and Bone Sarcomas

NCT02048722Phase 2Completed

Daily Oral Regorafenib for Chemotherapy-Refractory, Metastatic and Locally Advanced Angiosarcoma

NCT01532687Phase 2Completed

Gemcitabine With or Without Pazopanib in Treating Patients With Refractory Soft Tissue Sarcoma

NCT02609984Phase 2Terminated

Study to Compare the Safety and Efficacy of CMB305 With Atezolizumab to Atezolizumab Alone in Participants With Sarcoma (IMDZ-C232/V943A-002)

NCT02849366Phase 1CompletedPrimary

Combination of Cryosurgery and NK Immunotherapy for Recurrent Sarcoma

NCT01782313Phase 2CompletedPrimary

A Phase II Study of Tivozanib in Patients With Metastatic and Non-resectable Soft Tissue Sarcomas

NCT01154452Phase 1Completed

Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma

NCT01553539Phase 2Completed

Therapeutic Angiotensin-(1-7) in Treating Patients With Metastatic Sarcoma That Cannot Be Removed By Surgery

NCT00659360Phase 2Completed

AZD0530 in Treating Patients With Recurrent Locally Advanced or Metastatic Soft Tissue Sarcoma

NCT00089544Phase 2TerminatedPrimary

Preoperative Thalidomide With Radiation Therapy For Patients With Low-Grade Primary Soft Tissue Sarcoma or Thalidomide With Radiation Therapy and Chemotherapy For Patients With High-Grade or Intermediate-Grade Primary Soft Tissue Sarcoma of the Arm, Leg, or Body Wall

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