Key Insights

Highlights

Success Rate

82% trial completion

Published Results

13 trials with published results (8%)

Research Maturity

68 completed trials (41% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

9.0%

15 terminated out of 166 trials

Success Rate

81.9%

-4.6% vs benchmark

Late-Stage Pipeline

10%

16 trials in Phase 3/4

Results Transparency

19%

13 of 68 completed with results

Key Signals

13 with results82% success15 terminated

Data Visualizations

Phase Distribution

130Total
Not Applicable (63)
P 1 (11)
P 2 (40)
P 3 (11)
P 4 (5)

Trial Status

Completed68
Unknown44
Recruiting19
Terminated15
Active Not Recruiting8
Not Yet Recruiting7

Trial Success Rate

81.9%

Benchmark: 86.5%

Based on 68 completed trials

Clinical Trials (166)

Showing 20 of 20 trials
NCT04084249Not ApplicableActive Not Recruiting

ctDNA-guided Surveillance for Stage III CRC, a Randomized Intervention Trial

NCT07543848Phase 2Not Yet RecruitingPrimary

A Prospective, Multicenter, Single-Arm Phase II Exploratory Study of Serplulimab Combined With Oncolytic Virus H101, Short-Course Radiotherapy, and XELOX Chemotherapy as Total Neoadjuvant Treatment for Locally Advanced (cT1-3N0M0) Rectal Cancer

NCT05009069Phase 2Active Not RecruitingPrimary

A Study of Atezolizumab With or Without Tiragolumab Following Neoadjuvant Chemoradiotherapy in Participants With Locally Advanced Rectal Cancer

NCT07522294Not ApplicableActive Not RecruitingPrimary

Optimization and Standardization of Single-Port Robotic Transanal Minimally Invasive Surgery for Rectal Tumor Excision

NCT06417476Phase 2Active Not RecruitingPrimary

Short-course Radiotherapy or Long-course Chemoradiation Followed by mFOLFOXIRI Consolidation Chemotherapy for Organ Preservation in Low Rectal Cancer

NCT04075305Recruiting

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

NCT07419516CompletedPrimary

MRA Diameter as a Predictor for LLN Metastasis in Rectal Cancer.

NCT07376980Not ApplicableEnrolling By InvitationPrimary

The SMART Trial: Modified Single-Stapled Anastomosis in Laparoscopic or Robotic Low Anterior Resection for Rectal Cancer

NCT06426927Not ApplicableCompleted

PeLear CCC: Proyecto Latino Contra Cancer Colorrectal

NCT07346534Not ApplicableEnrolling By Invitation

Reinforced Versus Conventional Anastomosis in Laparoscopic Low Rectal Cancer Resection: A Comparative Study

NCT07154173RecruitingPrimary

Comprehensive Analysis of Gut Microbiota Signatures in Metastatic Colorectal Cancer

NCT05943444Not ApplicableRecruitingPrimary

Comparison of Postoperative Anal Function Between Parks and Bacon Techniques in Low Rectal Cancer

NCT07269912Not Yet RecruitingPrimary

Application of Multimodal MRI in Histological Grading and Prognostic Assessment of Rectal Cancer

NCT02505750Phase 3Active Not RecruitingPrimary

Safety of a Boost (CXB or EBRT) in Combination With Neoadjuvant Chemoradiotherapy for Early Rectal Adenocarcinoma

NCT05856305Phase 2Active Not RecruitingPrimary

SCRT in TNT With or Without Chlorophyllin

NCT04949646Not ApplicableRecruitingPrimary

Intraoperative Neuromonitoring of Pelvic Autonomous Nerve Plexus During Total Mesorectal Excision

NCT05789433Not ApplicableRecruiting

Effects of Aerobic Exercise on Skeletal Muscle Remodeling in Colorectal Cancer

NCT04926324Phase 1TerminatedPrimary

A Safety Study Adding Niraparib and Dostarlimab to Radiation Therapy for Rectal Cancers

NCT06902701Not Yet RecruitingPrimary

Endoscopic Submucosal Dissection vs. Transanal Endoscopic Surgery for Rectal Neoplasia

NCT04404777Active Not RecruitingPrimary

Local Recurrence Due to Rectal Cancer in Sweden

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