Key Insights

Highlights

Success Rate

79% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

15.4%

4 terminated out of 26 trials

Success Rate

78.9%

-7.6% vs benchmark

Late-Stage Pipeline

4%

1 trials in Phase 3/4

Results Transparency

33%

5 of 15 completed with results

Key Signals

5 with results79% success

Data Visualizations

Phase Distribution

19Total
Not Applicable (8)
Early P 1 (2)
P 1 (7)
P 2 (1)
P 3 (1)

Trial Status

Completed15
Recruiting6
Terminated4
Withdrawn1

Trial Success Rate

78.9%

Benchmark: 86.5%

Based on 15 completed trials

Clinical Trials (26)

Showing 20 of 20 trials
NCT04620382Early Phase 1Completed

Effect of Midodrine vs Abdominal Compression on Cardiovascular Risk Markers in Autonomic Failure Patients

NCT02429557Phase 1Completed

Hemodynamic Mechanisms of Abdominal Compression in the Treatment of Orthostatic Hypotension in Autonomic Failure

NCT03482297Phase 1Completed

Automated Abdominal Binder for Orthostatic Hypotension

NCT04246437Phase 1Recruiting

[18F]F-DOPA Imaging in Patients With Autonomic Failure

NCT03042988Not ApplicableRecruiting

Overnight Trials With Heat Stress in Autonomic Failure Patients With Supine Hypertension

NCT05489575Not ApplicableRecruiting

CPAP for the Treatment of Supine Hypertension

NCT02897063Phase 1Recruiting

Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure

NCT00775853Completed

Biomarkers of Risk of Parkinson Disease

NCT04782830Not ApplicableRecruiting

Use of Accelerometer for Quantification of Neurogenic Orthostatic Hypotension Symptoms

NCT01799915Recruiting

Natural History Study of Synucleinopathies

NCT04700722Completed

Synuclein-One Study

NCT03681080Not ApplicableCompleted

Concentration and Attentional Deficits in POTS and Other Autonomic Neuropathies

NCT02705755Phase 2Completed

TD-9855 Phase 2 in Neurogenic Orthostatic Hypotension (nOH)

NCT02417415Not ApplicableCompleted

Local Heat Stress in Autonomic Failure Patients With Supine Hypertension

NCT01119417Phase 1Withdrawn

The Role of Endothelin in the Supine Hypertension of Autonomic Failure

NCT04875949Not ApplicableCompletedPrimary

Anti-Cholinergic Receptors Antibodies, Autonomic Profile and Dysautonomia Symptoms in PAF, ALS and POTS (DISAUT-AB)

NCT02591173Early Phase 1Terminated

Blood Pressure Lowering Effects of Angiotensin-(1-7) in Primary Autonomic Failure

NCT02640339Completed

Retinal Abnormalities as Biomarker of Disease Progression and Early Diagnosis of Parkinson Disease

NCT01292694Phase 1Terminated

Contribution of Angiotensin II to Supine Hypertension in Autonomic Failure

NCT00179023Phase 1Completed

The Autonomic Nervous System and Obesity

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