Key Insights

Highlights

Success Rate

89% trial completion (above average)

Published Results

33 trials with published results (22%)

Research Maturity

104 completed trials (68% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 40/100

Termination Rate

8.5%

13 terminated out of 153 trials

Success Rate

88.9%

+2.4% vs benchmark

Late-Stage Pipeline

20%

31 trials in Phase 3/4

Results Transparency

32%

33 of 104 completed with results

Key Signals

33 with results89% success13 terminated

Data Visualizations

Phase Distribution

132Total
Not Applicable (38)
Early P 1 (4)
P 1 (19)
P 2 (40)
P 3 (15)
P 4 (16)

Trial Status

Completed104
Unknown13
Terminated13
Recruiting10
Not Yet Recruiting8
Withdrawn5

Trial Success Rate

88.9%

Benchmark: 86.5%

Based on 104 completed trials

Clinical Trials (153)

Showing 20 of 20 trials
NCT06800755Not ApplicableCompleted

Evaluation of the Efficacy and Tolerance of the Medical Device RL3020-DP0364 in Adult Population With Stable Mild Plaque Psoriasis, Dry Skin and Pruritus

NCT06593392Phase 2RecruitingPrimary

Safety and Tolerability of Difelikefalin in Adolescents on Haemodialysis With Moderate-to-Severe Pruritus

NCT06446609Recruiting

Drug-induced Liver Injury: Itching Study

NCT07450716Early Phase 1Not Yet RecruitingPrimary

Assessing the Efficacy and Safety of Photobiomodulation for the Treatment of Pruritus

NCT05263206Phase 3RecruitingPrimary

Efficacy and Safety of Subcutaneous Dupilumab for the Treatment of Adult Participants With Chronic Pruritus of Unknown Origin (CPUO) (LIBERTY-CPUO-CHIC)

NCT07478133Not ApplicableCompletedPrimary

Bioequivalence Study of Nalfurafine Hydrochloride Orally Disintegrating Tablets on Fasting and Fed in Humans

NCT07317271Not ApplicableRecruiting

VR-PMR for Post-Burn Symptoms

NCT07432386Phase 4Not Yet Recruiting

Methotrexate Versus Apremilast for Pruritus in Psoriasis

NCT02558738CompletedPrimary

Non Interventional Clinical Investigation of Ectoin Ear Spray in Skin Treatment of Outer Ear Canal Irritations

NCT03997851Phase 1CompletedPrimary

Topical Acetaminophen for Itch Relief: a Proof of Concept Study in Healthy Subjects

NCT04256759Phase 2CompletedPrimary

Dupilumab for the Treatment of Moderate to Severe Chronic Hepatic Pruritus

NCT06737484Not ApplicableCompleted

Effect of Topically Applied Olive Oil on Pruritus in Hemodialysis Patients: Pretest-posttest Model With Control Group

NCT06733519Phase 2Not Yet RecruitingPrimary

TH104 for the Treatment of Pruritus in Primary Biliary Cholangitis

NCT06751056Not ApplicableRecruitingPrimary

Cervical Traction to Reduce Gabaergic Medication Use for Neuropathic Itch

NCT04510090Phase 1CompletedPrimary

Evaluate the Safety, Tolerability, and PK of EP547 in Healthy Subjects and Subjects With Cholestatic or Uremic Pruritus

NCT05525520Phase 2CompletedPrimary

Study to Evaluate EP547 in Subjects With Cholestatic Pruritus Due to Primary Biliary Cholangitis or Primary Sclerosing Cholangitis

NCT04950127Phase 3CompletedPrimary

Global Linerixibat Itch Study of Efficacy and Safety in Primary Biliary Cholangitis (PBC) (GLISTEN)

NCT03458572Not ApplicableCompletedPrimary

Acupuncture for Prevention of Itch in Caesarean Section

NCT02143648Phase 2Completed

Study of Nalbuphine HCl ER Tablets in Hemodialysis Patients With Uremic Pruritus

NCT02143973Phase 2Completed

Open Label Extension Study of Nalbuphine HCl ER in Hemodialysis Patients With Uremic Pruritus

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