Key Insights

Highlights

Success Rate

76% trial completion

Published Results

15 trials with published results (22%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 39/100

Termination Rate

11.6%

8 terminated out of 69 trials

Success Rate

75.8%

-10.8% vs benchmark

Late-Stage Pipeline

29%

20 trials in Phase 3/4

Results Transparency

60%

15 of 25 completed with results

Key Signals

15 with results76% success

Data Visualizations

Phase Distribution

52Total
Not Applicable (6)
Early P 1 (1)
P 1 (6)
P 2 (19)
P 3 (14)
P 4 (6)

Trial Status

Completed25
Recruiting16
Terminated8
Unknown7
Active Not Recruiting6
Not Yet Recruiting6

Trial Success Rate

75.8%

Benchmark: 86.5%

Based on 25 completed trials

Clinical Trials (69)

Showing 20 of 20 trials
NCT06723275Recruiting

LEOPARD Prospective Validation Cohort 1

NCT06675604Recruiting

LEOPARD Training and Validation Data Collection Study

NCT07216235Phase 3RecruitingPrimary

Long-Term Study to Evaluate the Safety and Efficacy in Participants With Primary Biliary Cholangitis of Saroglitazar Magnesium-V on Clinical Outcomes

NCT06051617Phase 3RecruitingPrimary

Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis

NCT05239468Phase 2CompletedPrimary

Study of OCA in Combination With BZF Evaluating Efficacy, Safety and Tolerability in Participants With PBC

NCT04594694Phase 2TerminatedPrimary

Study of OCA in Combination With BZF Evaluating Efficacy, Safety, and Tolerability in Participants With PBC

NCT06383403Phase 3CompletedPrimary

A Study of Elafibranor in Adults With Primary Biliary Cholangitis and Inadequate Response or Intolerance to Ursodeoxycholic Acid.

NCT07282353Phase 3RecruitingPrimary

A Study of CS0159 in Patients With PBC With Inadequate Response or Intolerance to UDCA

NCT06447168RecruitingPrimary

A Study Observing Everyday Effectiveness and Safety of the Drug Elafibranor in Participants With Primary Biliary Cholangitis Who Are Receiving Ongoing Treatment

NCT06730061Phase 3Active Not RecruitingPrimary

A Study of Elafibranor in Adult Japanese Participants With Primary Biliary Cholangitis (PBC)

NCT06247735Phase 2Active Not RecruitingPrimary

Study to Evaluate the Efficacy and Safety of K-808 (Pemafibrate) in Participants With Primary Biliary Cholangitis (PBC) With Inadequate Response to Ursodeoxycholic Acid (UDCA) and/or Obeticholic Acid (OCA) Treatment.

NCT06488911Phase 3TerminatedPrimary

To Evaluate Safety and Tolerability of the Fixed- Dose Combination of Obeticholic Acid and Bezafibrate

NCT07629128Active Not RecruitingPrimary

Patients With Primary Biliary Cholangitis(PBC)

NCT06060665Phase 3CompletedPrimary

Intended to Determine the Effects of Seladelpar on Normalization of Alkaline Phosphatase Levels in Subjects With Primary Biliary Cholangitis (PBC)

NCT07598669RecruitingPrimary

Austrian PBC Registry

NCT05050136Phase 2RecruitingPrimary

A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary Cholangitis

NCT07424677Phase 3Not Yet RecruitingPrimary

Study of Saroglitazar Magnesium for PBC Patients With Incomplete Response or Intolerant to UDCA Therapy

NCT06427395Phase 3Active Not RecruitingPrimary

Open-Label Extension Study of Saroglitazar Magnesium in Participants With Primary Biliary Cholangitis

NCT05786482Not ApplicableCompletedPrimary

Evidence Based Mental Wellness Programming Online for Adults Across Chronic Physical Conditions

NCT07573514Not ApplicableActive Not RecruitingPrimary

Patients With Primary Biliary Cholangitis

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