Key Insights

Highlights

Success Rate

74% trial completion

Published Results

12 trials with published results (18%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 39/100

Termination Rate

11.9%

8 terminated out of 67 trials

Success Rate

74.2%

-12.3% vs benchmark

Late-Stage Pipeline

30%

20 trials in Phase 3/4

Results Transparency

52%

12 of 23 completed with results

Key Signals

12 with results74% success

Data Visualizations

Phase Distribution

52Total
Not Applicable (6)
Early P 1 (1)
P 1 (6)
P 2 (19)
P 3 (14)
P 4 (6)

Trial Status

Completed23
Recruiting14
Terminated8
Not Yet Recruiting8
Unknown7
Active Not Recruiting6

Trial Success Rate

74.2%

Benchmark: 86.5%

Based on 23 completed trials

Clinical Trials (67)

Showing 20 of 20 trials
NCT07573514Not ApplicableActive Not RecruitingPrimary

Patients With Primary Biliary Cholangitis

NCT05050136Phase 2RecruitingPrimary

A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary Cholangitis

NCT04950764Phase 1CompletedPrimary

An Open-Label Study Following Oral Dosing of Seladelpar to Participants With Primary Biliary Cholangitis (PBC) and Hepatic Impairment (HI)

NCT07319169Not ApplicableNot Yet RecruitingPrimary

The Value of Spleen Stiffness Measurement in Patients With PBC

NCT06447168RecruitingPrimary

A Study Observing Everyday Effectiveness and Safety of the Drug Elafibranor in Participants With Primary Biliary Cholangitis Who Are Receiving Ongoing Treatment

NCT06730061Phase 3Active Not RecruitingPrimary

A Study of Elafibranor in Adult Japanese Participants With Primary Biliary Cholangitis (PBC)

NCT06051617Phase 3RecruitingPrimary

Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis

NCT07049887CompletedPrimary

A Study Describing Scratch and Sleep Patterns in Patients With Primary Biliary Cholangitis (Luminaria)

NCT06383403Phase 3Active Not RecruitingPrimary

A Study of Elafibranor in Adults With Primary Biliary Cholangitis and Inadequate Response or Intolerance to Ursodeoxycholic Acid.

NCT05133336Phase 2CompletedPrimary

Saroglitazar Magnesium for Treatment of Primary Biliary Cholangitis

NCT05104853Phase 1CompletedPrimary

Study to Evaluate the Safety, Tolerability, PDs, and Efficacy of CNP-104 in Subjects With Primary Biliary Cholangitis

NCT07449793Recruiting

Biochemical Response and Clinical Outcomes in Patients With PBC

NCT07424677Phase 3Not Yet RecruitingPrimary

Study of Saroglitazar Magnesium for PBC Patients With Incomplete Response or Intolerant to UDCA Therapy

NCT07216235Phase 3Not Yet RecruitingPrimary

Long-Term Study to Evaluate the Safety and Efficacy in Participants With Primary Biliary Cholangitis of Saroglitazar Magnesium-V on Clinical Outcomes

NCT06427395Phase 3RecruitingPrimary

Open-Label Extension Study of Saroglitazar Magnesium in Participants With Primary Biliary Cholangitis

NCT06174402Phase 2Active Not RecruitingPrimary

Fenofibrate in Combination With Ursodeoxycholic Acid in Primary Biliary Cholangitis

NCT05751967Phase 3RecruitingPrimary

Fenofibrate Combined With Ursodeoxycholic Acid in Subjects With Primary Biliary Cholangitis

NCT05749822Phase 2RecruitingPrimary

Fenofibrate for Compensated Cirrhosis Patients With Primary Biliary Cholangitis

NCT07282353Phase 3RecruitingPrimary

A Study of CS0159 in Patients With PBC With Inadequate Response or Intolerance to UDCA

NCT04594694Phase 2TerminatedPrimary

Study of OCA in Combination With BZF Evaluating Efficacy, Safety, and Tolerability in Participants With PBC

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