Key Insights

Highlights

Success Rate

73% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 52/100

Termination Rate

13.7%

7 terminated out of 51 trials

Success Rate

73.1%

-13.4% vs benchmark

Late-Stage Pipeline

35%

18 trials in Phase 3/4

Results Transparency

21%

4 of 19 completed with results

Key Signals

4 with results73% success

Data Visualizations

Phase Distribution

32Total
Not Applicable (3)
P 1 (3)
P 2 (8)
P 3 (15)
P 4 (3)

Trial Status

Completed19
Recruiting9
Unknown8
Terminated7
Active Not Recruiting4
Not Yet Recruiting3

Trial Success Rate

73.1%

Benchmark: 86.5%

Based on 19 completed trials

Clinical Trials (51)

Showing 20 of 20 trials
NCT06331312Phase 3Active Not RecruitingPrimary

Open-label, Long-term Safety Study of Secukinumab in Polymyalgia Rheumatica (PMR)

NCT06647134Recruiting

A Qualitative Assessment of the Severity and Impact of Rheumatic Immune-Related Adverse Events Following Immune Checkpoint Inhibitor Immunotherapy

NCT06130540Phase 1Completed

Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Intravenous Secukinumab in Patients With GCA or PMR

NCT05435781Phase 4Recruiting

Effect of Supplemental Hydrocortisone During Stress in Prednisolone-induced Adrenal Insufficiency

NCT05767034Phase 3CompletedPrimary

Phase III Study of Efficacy and Safety of Secukinumab Versus Placebo, in Combination With Glucocorticoid Taper Regimen, in Patients With Polymyalgia Rheumatica (PMR)

NCT04402086Recruiting

Rheumatology Patient Registry and Biorepository

NCT07286214Phase 4Not Yet RecruitingPrimary

Sarilumab Efficacy and Safety in Adults With Early Polymyalgia Rheumatica

NCT07394478Not Yet Recruiting

Study of the Association Between Sacroiliitis/Axial Spondylarthritis and Giant Cell Arteritis/ Polymyalgia Rheumatica

NCT05533164Phase 3Active Not RecruitingPrimary

Rituximab Effect on Decreasing glUcoCorticoid Exposition in PolyMyalgia Rheumatica Patients Experiencing a PMR Relapse

NCT05533125Phase 3CompletedPrimary

Rituximab Effect on Decreasing glUcoCorticoid Exposition in PolyMyalgia Rheumatica Patients Recently Diagnosed

NCT05636501Not ApplicableActive Not RecruitingPrimary

Treat-to-target Prednisolon Taper in Patients With Polymyalgia Rheumatica

NCT04519580Active Not RecruitingPrimary

Improved Diagnostics and Monitoring of Polymyalgia Rheumatica

NCT07132164Not Yet RecruitingPrimary

Justification of the Initial Diagnosis and Evaluation of the Overall Evolution of a Cohort of Recent Polymyalgia Rheumatica (JADORE)

NCT06172361Phase 3RecruitingPrimary

Induction and Tapering Therapy With Tofacitinib and Glucocorticoid in Patients With Polymyalgia Rheumatica

NCT06281236Phase 1TerminatedPrimary

A Trial of Prednisolone in Combination With SPI-62 in Participants With Polymyalgia Rheumatica (PMR)

NCT05436652Phase 2CompletedPrimary

A Trial of Prednisolone in Combination With SPI-62 or Placebo in Subjects With Polymyalgia Rheumatica (PMR)

NCT06460142Recruiting

Assessing Biomarker in Giant Cell Arteritis and Polymyalgia Rheumatic

NCT04102930Recruiting

Clinical and Immunogenetic Characterization of Giant Cell Arteritis (GCA) and Polymyalgia Rheumatica (PMR)

NCT05542316CompletedPrimary

Validation of the PMR Activity Score and Evolution of Patient-reported Outcomes in Patients With Polymyalgia Rheumatica

NCT04664465Recruiting

PRediction of DIverse Glucocorticoids ToxIcity OUtcomeS

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