Key Insights

Highlights

Success Rate

29% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 65/100

Termination Rate

29.3%

12 terminated out of 41 trials

Success Rate

29.4%

-57.1% vs benchmark

Late-Stage Pipeline

12%

5 trials in Phase 3/4

Results Transparency

80%

4 of 5 completed with results

Key Signals

4 with results29% success12 terminated

Data Visualizations

Phase Distribution

40Total
Not Applicable (1)
P 1 (22)
P 2 (12)
P 3 (5)

Trial Status

Terminated12
Recruiting12
Unknown5
Completed5
Active Not Recruiting5
Withdrawn1

Trial Success Rate

29.4%

Benchmark: 86.5%

Based on 5 completed trials

Clinical Trials (41)

Showing 20 of 20 trials
NCT05271318Phase 1Active Not Recruiting

Oncolytic Adenovirus Coding for TNFa and IL2 (TILT-123) With Pembrolizumab or Pembrolizumab (Phase 1a) and Pegylated Liposomal Doxorubicin (Phase 1b) as Treatment for Ovarian Cancer.

NCT05551507Phase 1RecruitingPrimary

IN10018 in Combination With Standard Chemotherapy in High-grade Serous Epithelial Ovarian Cancer

NCT06619236Phase 3Active Not RecruitingPrimary

Study to Assess the Efficacy of Rina-S Compared to Treatment of Investigator's Choice in Participants With Platinum Resistant Ovarian Cancer

NCT06586957Phase 1Recruiting

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

NCT06515613Phase 1RecruitingPrimary

A Phase 1 Study of CTIM-76 in Patients With Recurring Ovarian Cancer and Other Advanced Solid Tumors

NCT07489287Phase 1Not Yet RecruitingPrimary

GB-5267 for the Treatment Platinum-Resistant Ovarian, Peritoneal, or Fallopian Tube Cancer

NCT05198804Phase 1Completed

A Study of Azenosertib (ZN-c3) and Niraparib in Subjects With Platinum-Resistant Ovarian Cancer

NCT05281471Phase 3RecruitingPrimary

Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)

NCT05494580Phase 1Completed

Pamiparib Plus Surufatinib in Patients With Platinum-resistant Ovarian Cancer

NCT07109414Phase 2Active Not RecruitingPrimary

Trial of NP-G2-044 (Prilukae) Combined With PLD for Treatment of Platinum-Resistant Ovarian Cancer (ULTIMUS-1)

NCT06730347Phase 2RecruitingPrimary

A Study of Lorigerlimab in Participants With Advanced Solid Tumors

NCT06321484Phase 1RecruitingPrimary

Intraperitoneal Cytokine-Induced Memory Like (CIML) Natural Killer (NK) Cells in Recurrent Ovarian Cancer

NCT05081609Phase 1Active Not Recruiting

A Study to Investigate Safety and Tolerability of TransCon IL-2 β/γ Alone or in Combination With Pembrolizumab and/or TransCon TLR7/8 Agonist or Other Anticancer Therapies in Adult Participants With Locally Advanced or Metastatic Solid Tumor Malignancies

NCT06242470Phase 1Recruiting

A Study of MGC026 in Participants With Advanced Solid Tumors

NCT05756907Phase 1Terminated

Combination of SON-1010 (IL12-FHAB) and Atezolizumab in Patients With Platinum-resistant Ovarian Cancer

NCT05483933Phase 1CompletedPrimary

Phase 1b Study of SL-172154 Administered With Combination Agent(s) in Subjects With Ovarian Cancers

NCT04504916Phase 2Terminated

A Study of Zilovertamab Vedotin (MK-2140/VLS-101) in Participants With Solid Tumors (MK-2140-002)

NCT07226427Phase 1RecruitingPrimary

A First-in-Human Study of MEN2501 in Participants With Platinum-Resistant Ovarian Cancer

NCT06710288Phase 2RecruitingPrimary

A Phase 2, Open-label, Single-arm Study Of Autologous M-CENK Adoptive Cell Therapy And N-803 (IL-15 Superagonist) In Combination With Gemcitabine In Participants With Recurrent Platinum-Resistant High-Grade Ovarian Cancer

NCT06315491Phase 2RecruitingPrimary

A Study of CBX 12 in Subjects With Platinum Resistant or Refractory Ovarian Cancer

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