Ototoxicity
22
3
4
11
Key Insights
Highlights
Success Rate
92% trial completion (above average)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 40/100
4.5%
1 terminated out of 22 trials
91.7%
+5.2% vs benchmark
18%
4 trials in Phase 3/4
27%
3 of 11 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 11 completed trials
Clinical Trials (22)
Protective Effect of Acetylcysteine Against Cisplatinum-Induced Ototoxicity: A Randomized Controlled Trial
Statins Effect on Incidence of Side Effects of Platinum Based Chemotherapy
Investigation of the Impact of Medications Used in COVID-19 Treatment and COVID-19 Vaccine on Hearing
Radiosurgery Induced Ototoxicity in Patients Treated for a Vestibular Schwannoma
Treatment of Radiation and Cisplatin Induced Toxicities with Tempol
SPI-1005 for Prevention and Treatment of Tobramycin Induced Ototoxicity
Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy
Intratympanic Administration of N-acetylcysteine for Protection of Cisplatin-induced Ototoxicity
Study to Evaluate Safety and Efficacy of DB-020 to Protect Hearing in Patients Receiving Cisplatin for Cancer Treatment
Preventing Nephrotoxicity and Ototoxicity From Osteosarcoma Therapy
Cisplatin With or Without Sodium Thiosulfate in Treating Young Patients With Stage I, II, or III Childhood Liver Cancer
Dexamethasone in Preventing Hearing Loss in Patients Receiving Cisplatin
SPI-1005 for Prevention and Treatment of Chemotherapy Induced Hearing Loss
Assessing Ear Damage in Young Cancer Patients Treated With Cisplatin
Alpha-Lipoic Acid in Preventing Hearing Loss in Cancer Patients Undergoing Treatment With Cisplatin
A Comparison of Infection Rates Between Two Surgical Sites
Observing Young Patients With Ependymoma Undergoing Standard Combination Chemotherapy
Aminoglycoside Plasma Level Measurement in Neonates With Infection
Intratympanic Steroid Treatment For The Prevention Of Inner Ear Toxicity Associated With Systemic Treatment With Cisplatin.
Intensity-Modulated Radiation Therapy or 3-Dimensional Conformal Radiation Therapy in Decreasing Hearing Loss in Patients Who Have Undergone Surgery for Parotid Tumors