Key Insights

Highlights

Success Rate

92% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 40/100

Termination Rate

4.5%

1 terminated out of 22 trials

Success Rate

91.7%

+5.2% vs benchmark

Late-Stage Pipeline

18%

4 trials in Phase 3/4

Results Transparency

27%

3 of 11 completed with results

Key Signals

3 with results92% success

Data Visualizations

Phase Distribution

16Total
Not Applicable (3)
P 1 (2)
P 2 (7)
P 3 (3)
P 4 (1)

Trial Status

Completed11
Unknown5
Recruiting3
Terminated1
Active Not Recruiting1
Withdrawn1

Trial Success Rate

91.7%

Benchmark: 86.5%

Based on 11 completed trials

Clinical Trials (22)

Showing 20 of 20 trials
NCT07364747Phase 2Recruiting

Protective Effect of Acetylcysteine Against Cisplatinum-Induced Ototoxicity: A Randomized Controlled Trial

NCT06553157Phase 1Completed

Statins Effect on Incidence of Side Effects of Platinum Based Chemotherapy

NCT07254442Completed

Investigation of the Impact of Medications Used in COVID-19 Treatment and COVID-19 Vaccine on Hearing

NCT05641441Recruiting

Radiosurgery Induced Ototoxicity in Patients Treated for a Vestibular Schwannoma

NCT03480971Phase 2Recruiting

Treatment of Radiation and Cisplatin Induced Toxicities with Tempol

NCT02819856Phase 2CompletedPrimary

SPI-1005 for Prevention and Treatment of Tobramycin Induced Ototoxicity

NCT00716976Phase 3Completed

Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy

NCT04226456Phase 4Terminated

Intratympanic Administration of N-acetylcysteine for Protection of Cisplatin-induced Ototoxicity

NCT04262336Phase 1CompletedPrimary

Study to Evaluate Safety and Efficacy of DB-020 to Protect Hearing in Patients Receiving Cisplatin for Cancer Treatment

NCT01848457Phase 2Completed

Preventing Nephrotoxicity and Ototoxicity From Osteosarcoma Therapy

NCT00652132Phase 3Completed

Cisplatin With or Without Sodium Thiosulfate in Treating Young Patients With Stage I, II, or III Childhood Liver Cancer

NCT02382068Not ApplicableWithdrawn

Dexamethasone in Preventing Hearing Loss in Patients Receiving Cisplatin

NCT01451853Phase 2Unknown

SPI-1005 for Prevention and Treatment of Chemotherapy Induced Hearing Loss

NCT00458887CompletedPrimary

Assessing Ear Damage in Young Cancer Patients Treated With Cisplatin

NCT00477607Phase 2CompletedPrimary

Alpha-Lipoic Acid in Preventing Hearing Loss in Cancer Patients Undergoing Treatment With Cisplatin

NCT01263262Completed

A Comparison of Infection Rates Between Two Surgical Sites

NCT00683319Active Not Recruiting

Observing Young Patients With Ependymoma Undergoing Standard Combination Chemotherapy

NCT01624324Unknown

Aminoglycoside Plasma Level Measurement in Neonates With Infection

NCT01285674Not ApplicableUnknown

Intratympanic Steroid Treatment For The Prevention Of Inner Ear Toxicity Associated With Systemic Treatment With Cisplatin.

NCT01216800Phase 3Unknown

Intensity-Modulated Radiation Therapy or 3-Dimensional Conformal Radiation Therapy in Decreasing Hearing Loss in Patients Who Have Undergone Surgery for Parotid Tumors

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Research Network

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